Random, interesting studies
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@Mauritio in my opinion it will be smarter to create a new post for each study so that they dont get drowned in a sea of others
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@lobotomize most of them are just random studies without much context. Usually when I create a thread I give more context. This serves more as a notepad. And if people look for a specific substance they will find it though the search function.
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@Mauritio just dropping a title about... doing... can make it have a much longer lifespan and can even help some random person years later (as many well named threads in the Rayp forum still do). Extra context can be retrieved by the average curious georgi with minimal tech literacy
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@lobotomize yeah you have a point. Maybe I'll make some of larger posts (like the coca one)into a thread.
When I start I never know what a posts turns out to be, because it depends how much fun it is to research it, so that's why i just drop all the studies here. -
Theobromine drastically Upregulated UCP1 AND PGC1a. Only in vitro, set still interesting.
Been wanting to try it for a while .
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@Mauritio - Have you considered food sources?
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@Mauritio - Have you considered food sources?
Foods Ranked 1 - 20 With Theobromine
My expectations for such a list were low but nevertheless beaten by such impressive stubborness:
It's only variations of cocoa and chocolate!
Now we know of your imaginations of a well-varied, balanced diet. Made me chuckle. -
@DavidPS yes, I like chocolate, but it contains too much heavy metals.
Has anybody tried theobromine as a supplement ? -
@Mauritio - thank you for bringing theobromine to my attention. I plan on trying it after things settle down after the holidays.
I am anticipating that theobromine will stress my nervous system in much the same way that caffeine stresses it and I plan on timimg my daily doses much like I do with coffee.

Health benefits and mechanisms of theobromine (2024)
Highlights
⢠Theobromine, a member of the methylxanthine class of compounds, has multiple potential health benefits.
⢠Theobromine acts as a non-selective antagonist of adenosine receptors, operates as a competitive and non-selective inhibitor of phosphodiesterases, and disrupts the activity of poly(ADP-ribose) polymerase 1 to exert its physiological functions. Theobromine, due to its low toxicity and versatility, can be employed as an additive in functional foods.
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@DavidPS said in Random, interesting studies:
I am anticipating that theobromine will stress my nervous system
Mind theobromine if weak cardia muscle (acid reflux)
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@DavidPS you're welcome.
Theobromine is supposed to be less stimulating for the CNS than caffeine.Here's another study where it strongly increased tyrosine hydroxilase and dopamine receptors in a mouse model of ADHD.