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    Random, interesting studies

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    • lobotomizeL Offline
      lobotomize @Mauritio
      last edited by lobotomize

      @Mauritio just dropping a title about... doing... can make it have a much longer lifespan and can even help some random person years later (as many well named threads in the Rayp forum still do). Extra context can be retrieved by the average curious georgi with minimal tech literacy

      MauritioM 1 Reply Last reply Reply Quote 1
      • MauritioM Offline
        Mauritio @lobotomize
        last edited by

        @lobotomize yeah you have a point. Maybe I'll make some of larger posts (like the coca one)into a thread.
        When I start I never know what a posts turns out to be, because it depends how much fun it is to research it, so that's why i just drop all the studies here.

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        • MauritioM Offline
          Mauritio
          last edited by

          Theobromine drastically Upregulated UCP1 AND PGC1a. Only in vitro, set still interesting.
          Been wanting to try it for a while .

          1000024569.png

          https://sci-hub.ren/10.1007/s12257-018-0434-y

          DavidPSD 1 Reply Last reply Reply Quote 0
          • DavidPSD Offline
            DavidPS @Mauritio
            last edited by

            @Mauritio - Have you considered food sources?

            Foods Ranked 1 - 20 With Theobromine

            Don't separate work and play; it is all play. šŸ‘€
            ā˜‚ļø

            C MauritioM 2 Replies Last reply Reply Quote 0
            • C Offline
              CrumblingCookie @DavidPS
              last edited by CrumblingCookie

              @Mauritio - Have you considered food sources?

              Foods Ranked 1 - 20 With Theobromine

              My expectations for such a list were low but nevertheless beaten by such impressive stubborness:
              It's only variations of cocoa and chocolate!
              Now we know of your imaginations of a well-varied, balanced diet. Made me chuckle.

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              • MauritioM Offline
                Mauritio @DavidPS
                last edited by

                @DavidPS yes, I like chocolate, but it contains too much heavy metals.
                Has anybody tried theobromine as a supplement ?

                DavidPSD 1 Reply Last reply Reply Quote 0
                • DavidPSD Offline
                  DavidPS @Mauritio
                  last edited by DavidPS

                  @Mauritio - thank you for bringing theobromine to my attention. I plan on trying it after things settle down after the holidays.

                  I am anticipating that theobromine will stress my nervous system in much the same way that caffeine stresses it and I plan on timimg my daily doses much like I do with coffee.
                  d21a095e-fd11-440c-8799-21d3c70c0353-image.png

                  Health benefits and mechanisms of theobromine (2024)

                  Highlights

                  • Theobromine, a member of the methylxanthine class of compounds, has multiple potential health benefits.

                  • Theobromine acts as a non-selective antagonist of adenosine receptors, operates as a competitive and non-selective inhibitor of phosphodiesterases, and disrupts the activity of poly(ADP-ribose) polymerase 1 to exert its physiological functions. Theobromine, due to its low toxicity and versatility, can be employed as an additive in functional foods.

                  Don't separate work and play; it is all play. šŸ‘€
                  ā˜‚ļø

                  LucHL MauritioM 2 Replies Last reply Reply Quote 1
                  • LucHL Online
                    LucH @DavidPS
                    last edited by

                    @DavidPS said in Random, interesting studies:

                    I am anticipating that theobromine will stress my nervous system

                    Mind theobromine if weak cardia muscle (acid reflux)

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                    • MauritioM Offline
                      Mauritio @DavidPS
                      last edited by

                      @DavidPS you're welcome.
                      Theobromine is supposed to be less stimulating for the CNS than caffeine.

                      Here's another study where it strongly increased tyrosine hydroxilase and dopamine receptors in a mouse model of ADHD.

                      https://www.researchgate.net/publication/380300570_Theobromine_improves_hyperactivity_inattention_and_working_memory_via_modulation_of_dopaminergic_neural_function_in_the_frontal_cortex_of_spontaneously_hypertensive_rats

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                      • MauritioM Offline
                        Mauritio
                        last edited by Mauritio

                        This post is deleted!
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                        • MauritioM Offline
                          Mauritio
                          last edited by

                          Aspirin alleviates fibrosis in mouse model. Hed~600mg.

                          https://pmc.ncbi.nlm.nih.gov/articles/PMC12226408/

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