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    • MauritioM Offline
      Mauritio @dapose
      last edited by

      @dapose I started taking frankincense too. The range of benefits is just too wide to ignore.

      I don't take Gonadin anymore. I think the old one was better and had some really interesting chemicals like Diosgenin or phytol in it.
      The new one makes me robotic.

      Dare to think.

      My X:
      x.com/Metabolicmonstr

      daposeD 1 Reply Last reply Reply Quote 0
      • daposeD Offline
        dapose @Mauritio
        last edited by

        @Mauritio yeah it seemed from that long thread that everyone was liking phytol and had definite productive responses to it… couldn’t tell why that needed to be changed. I’ll see how the new one goes. I really like the taste of the passionflower extract azf.

        1 Reply Last reply Reply Quote 0
        • C Offline
          CrumblingCookie @CrumblingCookie
          last edited by CrumblingCookie

          A Comparison of Sodium Citrate and Sodium Bicarbonate Ingestion: Blood Alkalosis and Gastrointestinal Symptoms, 2022

          500mg/KG BW sodium citrate (SC) is about equally effective as 300mg/KG BW sodium bicarbonate (SB) in raising blood pH and blood HCO3- in healthy people.
          The increase in the SC group however took about 1h longer to set in and also lasted for longer than the SB:
          full-ijsnem.2022-0083figuref1.jpg

          I'd say give the citrates a try for simplicity although in this study, the gastrointestinal side effects/complaints were comparable between SC (~35g!) and uncoated SB (~21g!).
          Whilst the SC also does meddle with stomach pH, it won't react to CO2 (burping, flatulence).
          The release of HCO3- from citrate happens indirectly through liver tricyclic-acid metabolism.

          And of course use potassium citrate or a citrates blend instead of the sodium salt.

          @mossy @ena There are several online suppliers of potassium citrate capsules (~1110mg per capsule, whereof 400mg K) as an affordable alternative to buying the pure powder and dissolving a teaspoon in water two times a day.

          10grs of potassium citrate contain about 3.6grs K, 10grs of potassium bicarbonate ~3.9grs K.
          Although the same amount (by weight) of citrate is not as effective as bicarbonate, on a regular daily basis I think one can shift between using either.

          E 1 Reply Last reply Reply Quote 0
          • E Offline
            Ena @CrumblingCookie
            last edited by

            Thank you @CrumblingCookie. Good information. But I see no financial advantage in citrate, here in the UK potassium citrate powder costs £14/kg and potassium bicarbonate £4/kg.

            1 Reply Last reply Reply Quote 0
            • MauritioM Offline
              Mauritio
              last edited by

              Protective Effects of Ginger against Aspirin-Induced Gastric Ulcers in Rats

              https://pmc.ncbi.nlm.nih.gov/articles/PMC3763798/

              Dare to think.

              My X:
              x.com/Metabolicmonstr

              1 Reply Last reply Reply Quote 2
              • MauritioM Offline
                Mauritio
                last edited by Mauritio

                Phytol

                Phytol lowers weight gain on a HFD. Drastically increases UCP1 (by 10x in white adipose tissue!), PGC1a and AMPK. It also strongly increases the most important enzyme for glucose oxidation, Pyruvate dehydrogenase (PDH).
                1000026062.png
                https://sci-hub.ren/10.1039/C7FO01817G

                "...PHY efficiently interacts with COX-1 and 2, NF-κB, and IL-1β. In conclusion, PHY exhibits anti-inflammatory activity, possibly via COX-1 and 2, NF-κB, and IL-1β dependent pathways."
                https://pubmed.ncbi.nlm.nih.gov/32583784/

                Phytol, Produces Antihyperalgesic, Anti-inflammatory, and Antiarthritic Effects
                https://pubmed.ncbi.nlm.nih.gov/32091204/

                Phytol seems to be a GABA-A receptor agonist, lengthening sleep time
                https://pubmed.ncbi.nlm.nih.gov/39357640/

                Again, it binds to GABA-A receptor, but also to 5HT1A. Not sure if it agonizes or antagonizes it.
                https://pmc.ncbi.nlm.nih.gov/articles/PMC11926570/

                Phytol drastically inhibits gastric ulcers
                https://pubmed.ncbi.nlm.nih.gov/38717706/

                Could be a dopamine d2 antagonist based on its antiemetic properties. But could also be due to possible 5ht3 antagonism (similar to ondansetron) .
                https://pmc.ncbi.nlm.nih.gov/articles/PMC10008523/

                Dare to think.

                My X:
                x.com/Metabolicmonstr

                daposeD 1 Reply Last reply Reply Quote 1
                • MauritioM Offline
                  Mauritio
                  last edited by Mauritio

                  Lemon balm / Melissa

                  Anti-estrogenic:

                  anti-cancer effect against breast cancer . Most effective against estrogen sensitive breast cancer.
                  https://pubmed.ncbi.nlm.nih.gov/32351599/

                  It decreases the severity of dismenorrhea, again pointing towards an anti-estrogen effect.
                  https://pmc.ncbi.nlm.nih.gov/articles/PMC6447884/

                  Decreases symptoms of PMS.
                  https://pmc.ncbi.nlm.nih.gov/articles/PMC4557408/

                  Anti- prolactin/Anti-TSH:
                  https://pubmed.ncbi.nlm.nih.gov/7202226/


                  Lowers weight gain on a HFD. Lowers FFAs and triglycerides.
                  https://sci-hub.ren/10.1016/j.jep.2020.113360

                  Dare to think.

                  My X:
                  x.com/Metabolicmonstr

                  daposeD 1 Reply Last reply Reply Quote 0
                  • MauritioM Offline
                    Mauritio
                    last edited by

                    Androgenic and aphrodesiac action of the medicinal plant Lithospermum Arvense (bird millet)

                    https://pubmed.ncbi.nlm.nih.gov/2743927/

                    Dare to think.

                    My X:
                    x.com/Metabolicmonstr

                    1 Reply Last reply Reply Quote 0
                    • daposeD Offline
                      dapose @Mauritio
                      last edited by

                      @Mauritio wow nice! And Lemon Balm is super easy to grow perennial herb. Available in most garden stores. Smells great too!

                      1 Reply Last reply Reply Quote 0
                      • daposeD Offline
                        dapose @Mauritio
                        last edited by

                        @Mauritio do you mess around with any phytol these days? Food or extract… is there a supplement phytol? Or just load up on the skins of nuts and slam seaweeds?
                        🌰

                        1 Reply Last reply Reply Quote 0
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