The path to infinite energy and youthfulness

NoeticJuice

@anib these might be of interest to you:

By the way, why do you want 5-HT1A and B antagonism?

rohmilchbubi

The 5-HT1A (dulling of erection, reduction of erectile blood flow) and 5-HT1B (sex drive, libido inhibition) receptors are involved in suppressing the male response to a woman. Therefore, the choice to antagonize these is primarily inspired by the pro-aphrodisiac effects of yohimbine, with which I am very satisfied, and the (excluded) metergoline.
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Thank you for the very interesting links. I skimmed through them and briefly explored some of the rabbit holes they led me to - various subreddits, users, blogs, etc. Due to the volume of information, I’ll return to it all in peace over the next days (or weeks).

What stood out positively: a massive aggregation or collection of both well-known and highly exotic molecules, so much new to explore and get inspiration from.
What stood out negatively: none of the texts or authors seem to make use of the creative potential that nootropics are supposed to unlock. Many of the writings and their presentation are simply boring and purely informational - a bad but very important sign that these substances haven’t truly activated the enormous creative possibilities within the authors themselves. (Btw. this is an important topic to discuss separately, what actually is the main purpose of nootropics, laser focused narrowmindedness vs free-associative thought streams vs playful-by-any-means raw output vs ...

rohmilchbubi

Some updates:

Clenbuterol (10–40 mcg) was unfortunately disappointing. It caused unpleasant heart palpitations even with minimal physical exertion. A further reduction in dosage and a different context might be necessary.
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Initial experiments with 20 mg Bromantane: minimally stimulating (increased dark circles under the eyes and slight facial muscle tension), auditory enhancement (music experience felt more immersive), increased thought flow (more associations and memory retrieval), enhanced affectivity and mood improvement. Later on, strong fatigue occurred (though not sure due to bromantane, as I had little sleep the previous night), brain fog.
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Upcoming experiments are planned with galantamine, TAK-653, sulbutiamine, and trans-Isrib.
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Ongoing experiments also include a change in the roa for 2C-B from oral to intranasal. I hope for improved context-sensitive kinetics (faster onset/peak/offset), increased comfort, and reduced body load
(maybe even s.c. or i.m., will see)