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Making progesterone at home

Bioenergetics Discussion
hormones
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  • J
    JamesL
    last edited by Feb 16, 2025, 2:54 PM

    Does anyone know how it can be done?

    The new batches of Progest-E cause me major estrogenic symptoms.

    A G 2 Replies Last reply Feb 16, 2025, 2:58 PM Reply Quote 0
    • A
      alfredoolivas @JamesL
      last edited by Feb 16, 2025, 2:58 PM

      @JamesL, do you mean produce the hormone itself? Impossible to be done at home unless you renovate your house into a lab

      However, you can get progesterone powder and make your own Progest E using vitamin E, if that is what you are enquiring.

      J 1 Reply Last reply Feb 16, 2025, 3:01 PM Reply Quote 0
      • J
        JamesL @alfredoolivas
        last edited by Feb 16, 2025, 3:01 PM

        @alfredoolivas I thought I had read something about Progest-E being made by extracting from a special type of sweet potato, is it that difficult?

        A L 2 Replies Last reply Feb 16, 2025, 3:19 PM Reply Quote 0
        • G
          gloryus @JamesL
          last edited by gloryus Feb 16, 2025, 3:09 PM Feb 16, 2025, 3:08 PM

          @JamesL getting estrogen symptoms from progesterone can be tissue estrogen being pushed into the blood and not being properly processed and removed through the live, bile and dietary fiber. If this might be the case for you, you could maybe try supplementing a little taurine to stimulate liver bile release and make sure to get your daily carrot salad or activated charcoal in.

          J G 2 Replies Last reply Feb 16, 2025, 3:14 PM Reply Quote 0
          • J
            JamesL @gloryus
            last edited by Feb 16, 2025, 3:14 PM

            @gloryus I don't get estrogenic symptoms from the old batches, I still have a few bottles

            1 Reply Last reply Reply Quote 0
            • A
              alfredoolivas @JamesL
              last edited by Feb 16, 2025, 3:19 PM

              @JamesL Yes, you need a lab to do that

              1 Reply Last reply Reply Quote 0
              • G
                gloryus @gloryus
                last edited by Feb 16, 2025, 3:23 PM

                @gloryus have you tried idealabs progesterone to see if you get the same effects? Pretty sure they go through a lot of effort to get the most pure ingredients available.

                J 1 Reply Last reply Feb 18, 2025, 4:15 PM Reply Quote 0
                • L
                  Luke @JamesL
                  last edited by Luke Feb 17, 2025, 2:23 PM Feb 17, 2025, 2:22 PM

                  @JamesL said in Making progesterone at home:

                  @alfredoolivas I thought I had read something about Progest-E being made by extracting from a special type of sweet potato, is it that difficult?

                  You can extract diosgenin from yams and synthesize Progesterone from that. But I don't think you can do that unless you are a chemist and have a lab with lots of resources.

                  Dr. Peat once mentioned that Progest-E is safe because it is refined further and further through a lot of steps. Even commercial products often have impurities and I suppose they have way better labs than any of us here has at home.

                  I've never been a big party attender, but I never went to a party where I didn't probably offend most of the people there by talking about what I was interested in. (Ray Peat)

                  1 Reply Last reply Reply Quote 0
                  • J
                    JamesL @gloryus
                    last edited by Feb 18, 2025, 4:15 PM

                    @gloryus No I haven't, his DMSO products affected me badly and I never trusted his products since

                    G 1 Reply Last reply Feb 18, 2025, 4:23 PM Reply Quote 0
                    • G
                      gloryus @JamesL
                      last edited by Feb 18, 2025, 4:23 PM

                      @JamesL Have you tried any other progesterone products like Ona's, Health Natura, or Forefront?

                      J 1 Reply Last reply Feb 19, 2025, 1:57 AM Reply Quote 0
                      • J
                        JamesL @gloryus
                        last edited by Feb 19, 2025, 1:57 AM

                        @gloryus yes Forefront, I didn't get the nice effects I used to get from the old Progest-E. Is there one you recommend?

                        G 1 Reply Last reply Feb 19, 2025, 3:04 AM Reply Quote 0
                        • G
                          gloryus @JamesL
                          last edited by Feb 19, 2025, 3:04 AM

                          @JamesL Another possibility is when ACTH is too high progesterone may not be metabolized into destressing pathways. At my worst I didn't feel anything positive from progesterone until I was taking a dose of cyproheptadine every 8 hours to suppress ACTH.

                          J 1 Reply Last reply Feb 22, 2025, 6:37 PM Reply Quote 0
                          • J
                            JamesL @gloryus
                            last edited by Feb 22, 2025, 6:37 PM

                            @gloryus I get great effects when I take the old bottles of Progest-E. I sleep noticeably better than normal and feel a sense of peace the next day. With the new bottles, I'm agitated and easily angered and my sleep isn't improved. Ray recommended Progesterone liberally, he never mentioned that people needed to do something in particular before using it to get good effects.

                            G 1 Reply Last reply Feb 22, 2025, 7:04 PM Reply Quote 0
                            • G
                              gloryus @JamesL
                              last edited by gloryus Feb 22, 2025, 7:06 PM Feb 22, 2025, 7:04 PM

                              @JamesL that's just my experience. No response whatsoever from prohormones in general without smashing cortisol/serotonin down first. You can probably do this naturally just by eating above maintenance and maybe some caffeine.

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