Chamomile has anti-estrogen and pro-progesterone properties
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350545/
This great study proves that chamomile can treat PCOS. Peat wrote that the causative factor of polycystic ovary syndrome is estrogen, which chamomile effectively reduces and significantly increases the level of progesterone.
Interestingly, many studies have shown that it actually lowers testosterone levels, but only in sick women. The opposite has been observed in men (increased testosterone levels)
This shows that chamomile has truly versatile effects. It has been known in herbal medicine for thousands of years.
,,In the study by Johari et al. entitled investigating the hydroalcoholic extract of chamomile on hypothalamus - pituitary- ovary axis of rats, chamomile caused significant reduction in the level of estrogen and significant elevation in progesterone. It also resulted in significant decline in the number of graph and primary follicles (16). Thus, chamomile is a phytoestrogen with antiestrogenic properties (lowering estrogen levels). This plant can function as a selective estrogen receptor, and this property can be harnessed in regulating endogenous estrogens in individuals with PCOS who have high estrogen levels. Chamomile has also progesterone effects which is effective in treating PCOS."
,,A review study by Arentz et al. with the aim of examining the effects of PCOS management and treatment using herbs showed regulation of ovulation, improvements in metabolic hormones as well as rate of fertility, oligomenorrhea, amenorrhea, and hyperandrogenism in PCOS patients (17)."
,,Overall, chamomile therapeutic regimen could relatively be effective in improving the hormonal parameters as well as oligomenorrhea and hirsutism in patients suffering from PCOS. Thus, based on the results of the present study, use of chamomile plant as a simple, inexpensive, and effective measure could be proposed for improving and treating patients with PCOS after confirmation by further studies with larger sample sizes."
https://pubmed.ncbi.nlm.nih.gov/31948119/
Perhaps chamomile also has a prothyroid effect, as it is known that hypothyroidism is crucial in the pathophysiology of ovarian cysts.
This study shows that chamomile has a thyroid-protective effect due to its antioxidant nature.
,, In conclusion, both Matricariachamomilla extract and metformin ameliorated hypothyroidism associated with PCOS through an antioxidant and antiapoptotic mechanism."
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Very cool. I guess this would partly explain the calming effect of chamomile tea.
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Isn't that caused by apigenin? Hans Amato talked positively about that.
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Depleta los niveles de neuroesteroides.
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Chamomile should be dried gently to not damage the tea compounds.
I recommend buying whole flower in bulk so you can see what you get. If you have a discerning palate you might taste certain bagged brands are toasted or bitter. There are inferior products out there so be careful.
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@Pillman said in Chamomile has anti-estrogen and pro-progesterone properties:
Chamomile should be dried gently to not damage the tea compounds.
I recommend buying whole flower in bulk so you can see what you get. If you have a discerning palate you might taste certain bagged brands are toasted or bitter. There are inferior products out there so be careful.
Agreed. Avoid bagged chamomile at all costs to be honest, it lacks active ingredients at best, and contains microplastics at worse.
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@Fructose Traditionally employed (among other things) to prevent frequent cramps and intestinal distress. And as a remedy for fungal infections when prepared as a bath.
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@Fructose what do you mean by ‘sick women’? What would sick mean in this case? PCOS is a sickness. What sickness are we talking about re lowering testosterone?
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it lowers testosterone in sick women… do most of the men in western society also be like sick women from the hormonal profile. hypothyroid, high estrogen, high cortisol, high prolactin……. So would be interesting if it also would raise T in them.
I drank last week every day chamomile tea, when I drank it in the afternoon or midday I get very sleepy. In the evening it doesn‘t help me too sleep, it lowers cortisol, but im lacking thyroid and then adrenaline kicks in
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@NangaParbat I will try it in a bath, never heard about it. Do you think its okay to mix with epsom salt?
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@Mr-X Can't imagine it would cause any problems
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@Mr-X He's probably a nocebo.
Generally, chamomile increases testosterone levels in men with PCOS, and lowers them in women with PCOS.
Chamomile per se stabilizes the hormonal balance.
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@Fructose said in Chamomile has anti-estrogen and pro-progesterone properties:
his plant can function as a selective estrogen receptor, and this property can be harnessed in regulating endogenous estrogens in individuals with PCOS who have high estrogen levels.
A detailed study showing the selective estrogen receptor modulator (SERM) properties of chamomille:
Greek Plant Extracts Exhibit Selective Estrogen Receptor Modulator (SERM)-like Properties
From the abstract: "...we submitted four plant aqueous extracts derived from
Greek flora (Sideritis euboea, Sideritis clandestina, Marticaria chamomilla, and Pimpinella anisum)
in a series of in vitro biological assays reflective of SERM profile. We examined their ability (a) to
stimulate the differentiation and mineralization of osteoblastic cell culture by histochemical staining
for alkaline phosphatase and Alizarin Red-S staining, (b) to induce, like antiestrogens, the insulin
growth factor binding protein 3 (IGFBP3) in MCF-7 breast cancer cells, and (c) to proliferate cervical
adenocarcinoma (HeLa) cells by use of MTT assay.
From Discussion:
(a) "Our study therefore, based on reliable biological tests and biochemical markers reflective of osteoblastic activity, reveals that the aqueous extracts of Sideritis euboea, Sideritis clandestina, Marticaria chamomilla, and Pimpinella anisum stimulated differentiation and mineralization significantly at a concentration range 50-25 µg/mL."(b) "The antiestrogenic effect of plant extracts on IGFBP3 levels was observed at a concentration of 10 µg/mL, whereas at higher concentrations (25-50 µg/mL), there was no effect. This is in agreement with previous reports, which demonstrate that plant extracts may exhibit differential activities over a physiological concentration range (being agonist or antagonist) suggesting an estrogen-receptor-mediated effect at low concentration and an ER-independent effect at higher concentration."
(c) "The absence of proliferative effects of the extracts on HeLa cells implicates that their action is neutral on these cells, at least via an EBS type II dependent mechanism."
@Kasper said:
Isn't that caused by apigenin?
"In our experiments, we cannot attribute the biological effects observed to particular constituents, because many other compounds are present in the plant extracts. Our study investigates the effect of the plant aqueous extracts as a whole on bone metabolism, as well as on breast and uterine tumor cells."
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@Pillman Do you have any brand recommendations?
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