Mysterious gallbladder disease - can't digest fat for no apparent reason
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@BearWithMe
Have a look into raising acetylcholine-dependent vagus-nerve regulation of intestinal motility and those esophagus-to-anus "rush waves" by replenishing with high-dose B5, along with alpha-GPC (or cholinebitartrate if you stand the fishy smell) and perhaps some R-ALA and thiamine to round it off wrt the pyruvate->acetate reaction by the PDH complex.
Should be similar in effect as but more fundamental than taking GABA powder.
Maybe that's a possible explanation for food not progressing through the GI system in an orderly fashion but staying in place for long times and with weird, nonproductive spasms/contractions until eventually more foods or liquids arrive to push it through those "static" sections. Which results in a skipping of those digestive sections and a symptoms complex of both lack of motility and diarrhea, maldigestion and malabsorption. All hypothetical!
Also, nicotine enhances the postsynaptic action of ACh through nicotinic ACh receptors. In the short term and if not overdone (because otherwise receptor densitiy will adapt). I suppose that's behind the infamous dump after a cigarette and coffee. -
@CrumblingCookie This makes a lot of sense. Thank you very much.
Almost all supplements cause rapid destruction of my teeth. They have the same effect (possibly even worse) when applied topically. B-Vitamins, choline, fat soluble vitamins, magnesium, zinc, gaba, iodised salt... I can't even use skin moisturizers because when I do, I'm losing teeth.
I can probably push through and take the supplements anyways but the toothache makes it very hard to eat. Also, I don't want to be toothless in my early 30s.
Maybe eradicating the pathogens in my gut first would help?
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@BearWithMe
I don't know what to make of those teeth issues.
If you really have significant fat malabsorption then those fatty acids in the lumen will saponify with Ca and Mg, preventing uptake of both. Any extra metabolic stimulus may raise the requirements for those minerals, besides perhaps also generating more endogenous oxalic acid, thus dissolving bone/teeth. -
@CrumblingCookie Also makes a lot of sense.
Should I keep my fat intake as low as possible? How much calcium should I supplement?
I'm worried that too much calcium carbonate long term might contribute to gastroparesis. I can't digest milk, calcium carbonate is my only source of calcium
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@BearWithMe
I think it's ideal to have about 200-300mg Ca per meal for absorption and for binding to dietary oxalic acid. Over the course of a day allegedly the average requirement is about 1200mg Ca.
Just do what's comfortable and makes sense to you.The Ca-carbonate will always neutralize some gastric acid.
You could get 80% L/R/+ lactic acid, dilute it down to 5% and use that every day to blend with your stash of Ca-carbonate to convert it to Ca-lactate. That won't further react with gastric acid and also provide some L-lactate as an energy source. And if mucosal skin works similarly as outer skin then lactate will stimulate cell renewal in the stomach and upper GI sections. -
@CrumblingCookie Oh, that's brilliant. I like this idea a lot. Thank you very much!
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Is it possible that I'm disrupting my peristaltis by eating too often (every 90 minutes or so)?
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Try eating strawberrys.
Whenever i get constipated, feeling bloated, and feeling as if the food is not being properly digested i eat strawberry.
I don't know how or why but it helps a lot.
I just smash a bunch of strawberry with sugar.
Half a cup of strawberry with two tablespoon of sugar.
Who knows it might help you.
And i think that lemon, orange or vinegar might make it worse - in my experience. -
Is it possible that I'm disrupting my peristalsis by eating too much fiber?
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Calprotectin: 27,78 ug/g (ref. range 0,00 - 50,00)
Candida albicans positive
Candida krusei negative
Candida glabrata negative
Candida dubliniensis negative
Candida parapsilosis negative
Candida tropicalis negative
Candida lusitaniae negativeGiardia lamblia negative
Entamoeba histolytica negative
Cryptosporidium spp. negative
Blastocystis hominis negative
Dientamoeba fragilis negative
Cyclospora cayetanensis negativeCampylobacter spp. negative
Yersinia enterocolitica negativeThe PCR results doesn't show quantity. Apparently having some C. albicans in digestive tract is normal? Should I assume there is an overgrowth? I have been using corticosteroids for asthma from 1996 to 2009.
I'm struggling to find any literature on oral dosing of borax. Is 1/4 to 1/2 tsp a day a reasonable dose? Would you provide some guidance in this regard, please? I'm also trying to obtain a prescription for Nystatin.
My digestion got significantly worse in past months. Reflux is so bad that my spit is dark brown and the constant nausea is almost unbearable.
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@BearWithMe what do you eat these days?
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@user2 Oats and meat. Added a bit of glucose powder recently, to make the oats more palatable and possibly for some health benefits
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@BearWithMe said in Mysterious gallbladder disease - can't digest fat for no apparent reason:
@user2 Oats and meat. Added a bit of glucose powder recently, to make the oats more palatable and possibly for some health benefits
did you try differents types of fat sources, avocado, nuts, beef fat, lamb fat,eggs, olives, if yes, same effects from any of these sources, or it vary?
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@user2 Haven't had most of these foods in very long time, I'm not sure I can answer your question. I think fat source / type doesn't matter that much but I'm not sure.
Solid fat seems to digest significantly better than liquid fat, though. When I eat lard, tallow or coconut oil, I always make sure it is as cold as possible.
Liquid fat mixed with other stuff is the worst. Last time I had homogenized milk, it caused agony so bad I'd rather die of hunger than touching milk ever again. But any liquid fat mixed with small particles of other stuff causes similar reaction.
Liquid fat on pasta = okay-ish in small quantities
Liquid fat in mashed potatoes or porridge = agony -
I should probably say that I would not desribe this as gallbladder disease anymore. Sugars and carbs cause almost the same symptoms as fat. Protein doesn't cause obvious symptoms even in high quantities but I probably can't digest it either. Everything is passing through undigested.
I called it "gallbladder disease" because the discomfort is often felt in upper right part of the abdomen
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@BearWithMe said in Mysterious gallbladder disease - can't digest fat for no apparent reason:
I should probably say that I would not desribe this as gallbladder disease anymore. Sugars and carbs cause almost the same symptoms as fat. Protein doesn't cause obvious symptoms even in high quantities but I probably can't digest it either. Everything is passing through undigested.
I called it "gallbladder disease" because the discomfort is often felt in upper right part of the abdomen
i suggest retry different fat sources such avocado, olives, subcutanous fat from lamb, hazelnuts, macadamia and see if they have same effects or different. have you tryed fruits, if yes wich ones? how do you feel from sunlight exposure?
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It might seem too obvious
Or
Just the last thing you are thinking?But
The diet you are on now
It is NOT working for youI would step back
Pull back
And start from scratchNo supplements
Easy to digest foods (ie mashed potatoes, stews, jasmine rice puddings etc)You’re body is screaming for change…
The further society drifts from the truth the more it will hate those who speak it.
SD
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Your diet looks dreadful @BearWithMe
I understand that this present diet of yours is because you cut out all the offending foods -- but at the same time I think something has to change for you to heal. In my experience oatmeal in large quantities is guaranteed to wreck gut health and your diet is also severely lacking in calcium and other important nutrients.
Are there any other food you can tolerate besides oats and meat?
You wrote in a previous post that rice noodles are okay. Can you eat lean meat, rice noodles and super well-cooked broccoli? That would be a better staple meal than oats and lean meat
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@BearWithMe said in Mysterious gallbladder disease - can't digest fat for no apparent reason:
I'm struggling to find any literature on oral dosing of borax. Is 1/4 to 1/2 tsp a day a reasonable dose?
1/2 a teaspoon would be about 2.5ml*1.73g=4.33g borax, *0.11=475mg of boron. That's terribly much. Won't cause any lasting harm, though. IME a maximum of 30-40mg of boron per dosing was alright. 2-3 times a day. That's about 300mg of borax per dose. One can also just do a third or a tenth of that. Always start low.
Sad to read that your digestion has been on further decline : /.
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@Peatful This idea definitely crossed my mind. The problem is, pretty much any food is causing similar or even worse symptoms. But I will replace oats with something else (rice?) immediatelly because I can't eat any more oats even if I wanted to.
@user2 Fruits were my primary source of energy from 2014 to 2024. Oranges, grapes, bananas, plums... Have stopped eating fruits because they destroyed my teeth. Also, I think they stimulate metabolic rate too much when eaten in large quantities
Sunlight feels very good for a couple of minutes, then it causes stress reaction (high pulse, palpipations, shortness of breath etc)
@Korven I agree something must change. Not sure if rice is the answer, though? Rice is almost devoid of nutrients. Oats, while by no means complete, have very good mineral profile. Interestingly enough, I've had intense cravings for rice noodles recently.
Whey protein powder and fruits doesn't cause obvious digestive symptoms in any quantity, but have other problems so they are not an option. Not sure what else to try. Corn maybe? I've had good experience with corn in the past
@CrumblingCookie Thank you. Appreciate this very much
