Coffee dries out skin and eyes, like finasteride, dutasteride and accutane
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@alex155 Interesting research, thanks.
Have you also considered the importance of copper and its role in balancing zinc?
https://pmc.ncbi.nlm.nih.gov/articles/PMC4556990/
In the skin, copper is involved in the synthesis and stabilization of extracellular matrix skin proteins
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@Kvirion thank you very much! yes, I didn't think about copper, I need to try it
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I got it,
all these products are also strong aromatase inhibitors...
low DHT, plus low estrogen - makes you a real castrate! I
should reduce aspirin to at least one 100mg tablet every three days. By the way, UDCA also destroys all estrogen, and I've been taking it for 3 years -
A alex155 referenced this topic on
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By the way, zinc bisglycinate, unlike the sulfate and citrate forms, does not cause dry skin, but no more than 25 mg per day.
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@PissBoy Very interesting.
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At least coffee can be multifaceted-ly beneficial, when taken in the right amounts and with cream and sugar.
Fina steride seems to be completely destructive. -
Coffee helps with:
Fighting Melanoma
Oral health
Keep ing Cortisol down
Liver health
Protecting against Senility
Maintain ing DNA integrity
Prevent ingTinnitus
Cancer, particularly liver cancerhttps://lowtoxinforum.com/search/2631402/?q=Coffee&c[title_only]=1&c[users]=Haidut&o=relevance
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This is interesting but I think it can be helpful to take breaks from coffee. Like, try to go to sleep and just wake up naturally on time, have the energy to sleep deeply. Not saying it's easy I just feel less reliant on coffee though. It helps, but I used to rely on it very heavily.
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good luck with your castration, Chuckie, with high doses of B6 and zinc:
https://pubmed.ncbi.nlm.nih.gov/3207614/
Abstract
The effects of zinc sulphate and azelaic acid on 5 alpha-reductase activity in human skin were studied using an in vitro assay with 1,2[3H]-testosterone as substrate. When added at concentrations of 3 or 9 mmol/l, zinc was a potent inhibitor of 5 alpha-reductase activity. At high concentrations, zinc could completely inhibit the enzyme activity. Azelaic acid was also a potent inhibitor of 5 alpha-reductase; inhibition was detectable at concentrations as low as 0.2 mmol/l and was complete at 3 mmol/l. An additive effect of the two inhibitors was observed. Vitamin B6 potentiated the inhibitory effect of zinc, but not of azelaic acid, suggesting that two different mechanisms are involved. When the three substances were added together at very low concentrations which had been shown to be ineffective alone, 90% inhibition of 5 alpha-reductase activity was obtained. If this inhibition is confirmed in vivo, zinc sulphate combined with azelaic acid could be an effective agent in the treatment of androgen related pathology of human skin.
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@alex155
effects could be different from adding other components of the formula. there's people with testosterone increased from HG7
but that's an interesting study yeah -
@teamfortress too many 5-ar inhibitors bro...
https://pubmed.ncbi.nlm.nih.gov/11380153/
Abstract
Hamster flank organ growth, as measured by an increase in the area of the pigmented macule, is androgen-dependent. When flank organs of a castrated hamster are treated topically with testosterone, the flank organ becomes larger and darker. Since this growth is known to be dependent on the intracellular active androgen, 5alpha-dihydrotestosterone (DHT), inhibitors of 5alpha-reductase which converts testosterone to DHT can inhibit the growth of the flank organ. Certain unsaturated aliphatic fatty acids, such as gamma-linolenic acid and myristoleic acid, as well as other natural compounds, including alizarin and curcumin, are 5alpha-reductase inhibitors and inhibited flank organ growth. Green tea catechins, including (-)-epicatechin-3-gallate, and (-)-epigallo-catechin-3-gallate (EGCG) are also 5alpha-reductase inhibitors and inhibited flank organ growth. However, (-)-epicatechin and (-)-epigallocatechin, which are not 5alpha-reductase inhibitors, also inhibited flank organ growth. EGCG also inhibited DHT-dependent growth of flank organs. These catechins, therefore, may act by a mechanism other than inhibition of 5alpha-reductase. The effect of EGCG and other compounds was localized at the site of application; they did not affect the growth of the contralateral flank organ in the same animal. Since these compounds do not appear to exhibit systemic effects, they may be potentially useful for treatment of androgen-dependent skin disorders.
