@eduardo-crispino

Peatbot: Ray Peat mentioned that he has been looking for the real beneficial effects of THC and CBD, but he finds the effects to be very ambiguous. He noted that in some circumstances, they can be anti-inflammatory, but not always. He expressed that he hasn't been able to resolve the ambiguity to form a definite opinion on the matter.

And from peaty friendly Analyze & Optimize:

What they tell you weed does:

Nothing, it's harmless

What it really does:

☒ Decreases key neurotransmitters (dopamine, acetylcholine, GABA, glutamate)
☒ Reduces brain volume
☒ Alters brain structures (amygdala, nucleus accumbens)
☒ Reduces reward perception
☒ Reduces separation of logic & emotion
☒ Impairs memory
☒ Impairs mitochondrial function
☒ Lowers IQ
☒ Increases depression risk
☒ Increases anxiety risk
☒ Increases risk of suicidal ideation
☒ Drastically increases risk of schizophrenia
☒ Massively increases risk of psychosis
☒ Increases risk of several cancers (all head + neck, laryngeal, nasopharyngeal, oral, oropharyngeal, salivary gland, testicular)
https://x.com/Outdoctrination/status/1903043866640437563

@CrumblingCookie said in All things Histone Deacetylase (HDAC) and DNA Methyl Transferase (DNMT) inhibitory - reversing epigenetics from metabolic insults:

What do you remember about them?

It was before peating. I had IBS-D, and butyrate increased my fluctuance and GI discomfort and probably forced me to visit the toilet more often...

Regarding apigenin, I'm interested in your experiences.
BTW, what do you think about some MAO-A inhibition by apigenin?
https://link.springer.com/article/10.1007/BF02977772

@CrumblingCookie said in All things Histone Deacetylase (HDAC) and DNA Methyl Transferase (DNMT) inhibitory - reversing epigenetics from metabolic insults:

Thank you for sharing. I learned a lot

Here is why he maybe didn't warm up to SCFAs like butyrate, as he connected their synthesis to the many drawbacks associated with the abundance of gastrointestinal bacterial fermentation [...]

Yeah, this explains my negative experiences with butyrate a long time ago...

An update about the mRNA vaccine's "safety"...
https://www.youtube.com/watch?v=s9tlqUjwAvg

@jamezb46 said in Knowledge is Power:

If true, it means that truth is dead. It means that our understanding, like a bird with broken wings, tries to fly toward truth but crashes to the earth.

Welcome to the real world, Neo...

Most people can only perceive (superficial) symbolic interpretations of the world, which society tells them to believe in...

If you wanna know more, just read Simulacra and Simulation...

BTW

@DavidPS Thank you!

It's good to see him again after a long absence from YouTube.

Oranges and cherries. Black berries juice from time to time.

@gg12 said in just3another3normal3person:

The universe is governed by mathematical destiny.

No, it's an idealistic, platonic view.
Ray didn't like Plato - and correctly criticised his views - like in the following article: https://raypeat.com/articles/articles/howdoyouknow.shtml

Some other people just think that Plato simply didn't have the balls to see/admit that the universe is always in motion - uncertain and volatile. Therefore, he invented static forms and ideas to calm his anxieties.

The universe is in a dynamic homeostasis - constantly changing and adapting.

BTW, our world isn't in our heads - it is in the interactions between our minds and matter...
https://social-epistemology.com/2024/12/04/towards-a-new-materialism-a-comment-on-armstrongs-life-mind-and-matter-victor-de-lorenzo/

@Luke Yeah! Kudos to the admins for cleaning up.

Additionally, we may need to have some automatic rules, such as new users can't create more than x new threads per day, etc.
Or something like: if a few senior users (more than 100 posts) mark something as spam, such thread will automatically be deleted...
But I don't know if the forum's software allows this...

@alfredoolivas Yeah, I see your point.

I guess it would be better to exchange the category name for "mediators" - ones who don't like their friends fighting each other and try to establish consensus or mutual understanding. This will fit more with empathy.

But this is one of my reservations about this study - categories seem to be too broad... too generalized.

Or maybe this study should be seen just as a study of dating sites'' members nothing more...

I tend to see noticable kindness as a bad first impression when I meet someone.

This may be highly context/culture-dependent...