Long-Chain Omega-3 Fatty Acids (DHA and EPA) in Aging
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I eat fish 2-3 times a week. I do not take fish oil capsules or algea capsules, I consider them to be ultraprocessed foods.
The article below describes the science behind the benefits of long-chain omega 3 fatty acids. It has hotlinks to the studies it discusses.
Follow the science?
All you need is love. But a little chocolate now and then doesn't hurt.
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@otto said in Long-Chain Omega-3 Fatty Acids (DHA and EPA) in Aging:
Follow the science?
No. Mainstream is colored by labo. Short term target
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The fake healthy oils are sold in health store coops. You won't see a lot of women getting old gracefully there. Wonder why they have so much dry grey hair and dry wrinkling faces?
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Benefits of Omega-3?
No one disputes the benefits of omega-3s on inflammation (particularly EPA), blood fluidity, and countering the overreaction of the immune system. Studies on the benefits of a molecule rarely exceed 12 weeks.
Excerpt: Antithyroid Effects of Omega-3s
Administration of ALA results in a 22% reduction in T3, the most potent form of thyroid hormone. T4 to T3 conversion rates decrease by 56% in response to ALA ingestion. ALA even interferes with normal T3 levels if you pre-administer T4 into the cells. (10)
10. http://www.ncbi.nlm.nih.gov/pubmed/1815532
Clipping the Wings of a Lame Duck
Yes, omega-3s taken as a course of treatment have an anti-inflammatory effect. Here, it's the word "course" that's important. This article is not about avoiding omega-3 intake through a varied diet, sourced from whole foods. For example, according to this JAMA study (meta-analysis), depending on the type of diet (with white or oily fish twice a week), the risk of cardiovascular disease with supplementation is reduced by 30%. (2-5) There is a correlation between membrane fluidity and mitochondrial health. But don't overdo it, otherwise the collateral damage caused by peroxidation will be much more harmful. (6)To be continued at this link (in French, translator required), with references in English (studies).
https://mirzoune-ciboulette.forumactif.org/t2106-huile-de-petits-poissons-gras-et-effets-sur-la-thyroide#30186
Useful links
*) Huile de poisson et effet sur la thyroïde (Fish oil and its effect on the thyroid)
Ray Peat Ph.D. – Kate Deering – Dr. Rita Lee – Etc.
https://mirzoune-ciboulette.forumactif.org/t1388-huile-de-poisson-et-effet-sur-la-thyroide#15791
Effet anti-thyroïdien et digestif sur les enzymes. + Impact sur le niveau d’énergie.
*) Les besoins réels en AG polyinsaturés surestimés ? (Are the real needs for polyunsaturated fatty acids overestimated?)
https://mirzoune-ciboulette.forumactif.org/t1581-les-besoins-reels-en-ag-polyinsatures-surestimes#18738 -
Bro just eat a can of oysters once or twice a week...done. There's never a reason to put any thought into "getting your omega-3's."
Also a lot of those perceived benefits of omega-3's are probably coming from selenium (also rich in seafood).
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I take the position that JAMA frames the supposed salutary effect of omega-3s as solely based on how it is anti-inflammatory and supposedly beneficial from the standpoint that all inflammation is bad.
But inflammation is part of the healing process. When there is trauma or infection, inflammation is needed to allow white blood cells inside tissues to effect repair. We see this when we get injured and we see this when there in infection.
To simply say that omega-3s are good because it is anti-inflammatory is like saying all oxidative processes are bad because antioxidants are good, which isn't the case as the simplistic association is just misleading.
I also don't take much stock in meta-analysis. It's like 10 dogs outnumbering humans in an election and dogs getting their candidate to win. If there are 10 flawed studies with conclusion A and only 2 good studies with a conclusion B, hands down conclusion A wins.
