Thyroid regrets
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I took low doses of cynoplus and cynomel for a few weeks. Felt alive like never before for a few days until the T4 caught up with me and I went hyperthyroid for a few days. I slowly tapered off T4 as of 2-3 weeks ago and now have been off everything for a week. It appeared to be a low cholesterol issue.
Now my vision is blurry. My right arm and leg regularly tingle. I have to monitor my blood sugar. The top of my head often tingles too, and I’m losing hair.
If you have advice for what to do about any of this, great. If not, I post this as a cautionary tale. Just take it easy. -
I would eat robustly
Foods that I know agree with me- easy to digest ones50/20/20 or 40/30/30 ratio
Get your glycogen stores back up
Seems like you burnt right through them so to speak -
@Peatful I’ll see what I can do. Having to spread sugars throughout the day so it’s a challenge.
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@schemingfonzie why do you think your thyroid was low?
For me I'm pretty sure it was due to heavy metals and I've noticed symptoms crop up again as I increase my temperature. I'm just going slowly with it -
@Living_thing not sure, really. Been a fat kid despite not eating that much since about 8 years old.
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@schemingfonzie Sounds like an adrenaline reaction more than going hyper. How do you know you were hyperthyroid?
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@BroJonas I know the symptoms of the two overlap a lot but they map perfectly to my increase and decrease of thyroid dosage
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@schemingfonzie Yeah the increase thyroid makes you more sensitive to adrenaline, but over time it helps lower its output.
I’ve experienced this myself, took some trial an error to get over that
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Hans selye wrote in his epic book it takes up to two months so a few weeks aint much
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@heyman if it were an elevated heart rate or something, I’d be ok with riding it out. The diabetic scares and screwed up vision are too concerning for “wait and see,” imo.
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@schemingfonzie said in Thyroid regrets:
If you have advice for what to do about any of this, great. If not, I post this as a cautionary tale. Just take it easy.
Lack of cofactors for T4 to T3 Conversion
When taking synthetic T3 and T4 supplement, you lack cofactors.
Exhausted after a few months. Required for deiodinase 3.Detailed explanation:
A deficiency in cofactors, particularly those required for deiodinase 3, can lead to exhaustion and may be a factor in why you feel depleted after a few months.
T4 to T3 conversion
Impaired conversion of T4 to T3, due to cofactor deficiencies, can lead to a state of apparent thyroid dysfunction, where individuals may experience both hypothyroidism and hyperthyroidism-like symptoms, or even a mix of both. This is often seen in conditions where the body has difficulty converting T4 (thyroxine), the less active thyroid hormone, into T3 (triiodothyronine), the more active form. Deficiencies in certain cofactors, like selenium, zinc, or iron, can hinder this conversion process.
Here's a more detailed explanation:
• Cofactor Deficiencies:
T4 to T3 conversion relies on enzymes that require specific cofactors. Selenium is a crucial component of the deiodinase enzymes responsible for this conversion. Zinc and iron are also involved in thyroid hormone production and metabolism. Deficiencies in these nutrients can disrupt the conversion process.
• Reverse T3 (rT3):
In cases of impaired T4 to T3 conversion, because of a lack of cofactors when supplementing with synthetic T3 and T4, T4 is going to accumulate. The body may also shunt T4 towards the production of reverse T3 (rT3), an inactive form of thyroid hormone. High rT3 levels can further contribute to the mixed symptoms of thyroid dysfunction.
• Clinical Considerations:
It's important to note that in cases of impaired T4 to T3 conversion, the typical thyroid function tests (TSH, T4, and T3) may not always accurately reflect the underlying issue. Testing for rT3 and assessing for cofactor deficiencies may be necessary for proper diagnosis and management.
• Treatment:
Addressing the underlying cofactor deficiencies is crucial in these cases. Supplementation with selenium, zinc, or iron, as appropriate, can help improve T4 to T3 conversion and alleviate the associated symptoms. The brain need time to adapt to the situation when changing the posology (progressively, and every 7-10 days).
Note: Supplementing with iodine should be made with caution to avoid a Wolff-Chaikoff effect. 150 – 250 mcg kelp (titrated dose with K- and K2; both are required). -
I've overdone thyroid before and the nerve-damage type symptoms will go away and you will recover.
Some thiamine, niacinamide, and a couple months of decent eating and rest and you should be back to normal.
