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    Scrotal Testosterone Base: Cream Solubility Issues & Gel Alternative?

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    • R
      ruben352
      last edited by

      Hey guys,

      I’m new here and found this forum while looking for info about DHT.
      I read that applying testosterone base on the scrotum can raise DHT quite a lot because of the enzyme activity there, and that it may also lead to lower estrogen.

      I tried making a 20% testosterone cream, but it turned out kind of sandy — seems like it didn’t dissolve well, even though I used a TRT base cream with 20% propylene glycol in the mix.

      Now I’m thinking about trying a gel instead — maybe something like 80% propylene glycol and 20% ethanol, since ChatGPT mentioned that this might absorb as well or even better than a cream.

      Has anyone here tried this?
      Or maybe even done blood panels with such a setup?

      Thanks in advance!

      lobotomizeL C 2 Replies Last reply Reply Quote 0
      • lobotomizeL
        lobotomize @ruben352
        last edited by lobotomize

        @ruben352 for what I know applying stuff into a compact organ which needs to regulate its temperatures fat vitamin amino minerals balance isn't the best idea. Focus on raising 5ar through diet. Keeping that in mind @Mauritio has an old post mentioning that taurine increases favourable enzymes such as 5ar and star

        1 Reply Last reply Reply Quote 0
        • C
          CrumblingCookie @ruben352
          last edited by CrumblingCookie

          @ruben352
          For increasing lipophilic hormone solubility in and absorption from aqueous solutions consider dissolving with HPbCD in a 1:2 molar ratio. Please post further findings and results.

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