Anybody used LipOdd or MitoLipin or DeFibron?
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@sunsunsun It's a half truth because much higher doses are needed? Yes some phosphatidyl choline will stay intact, but most just breaks down into choline, glycerol and a fatty acid.
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@alfredoolivas Someone should dissolve Haidut's product in a 2-3 pH solution of hydrochloric acid and see what happens to it
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@alfredoolivas Interesting. Then why do you think that European countries use soy-derived phosphatidylcholine to treat FLD? Do you think that population would benefit just as much from other sources of choline?
The german manufacturer lipoid, for example, claims that
" The benefits of natural phosphatidylcholine over artificial choline salts:
- Phosphatidylcholine can be efficiently processed by the body via natural pathways to form new cell structures
- Phosphatidylcholine has an enhanced bioavailability and faster absorption
- Due to the effective natural uptake, phosphatidylcholine does not reach the large intestine and therefore is not converted into transmethylamine-N-oxide (TMAO) by gut microbes
- In addition to choline, phosphatidylcholine provides essential unsaturated fatty acids that contribute to its health benefits "
https://lipoid.com/en/2024/11/20/phosphatidylcholine-more-than-just-choline/
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@jamezb46 Phosphatidylcholine is the form least likely to raise TMAO as far as I know, maybe CDP choline is better in that regard. I think that's why it is used.
Why do you want to dissolve Mitolipin?
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@alfredoolivas Becuase if adding mitolipin to a solution of HCL causes the phosphatidylcholine to break down that suggests that the same thing would happen when we eat it.
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@alfredoolivas Even 1.5 is a huge amount for me, do you ever drink that much?
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@alfredoolivas i might try this
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@sunsunsun @engineer I am experimenitng with 3l and 150g of grana padano
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Actually, I will be increasing the milk to 4l and removing the grana padano.
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@alfredoolivas said in Anybody used LipOdd or MitoLipin or DeFibron?:
Actually, I will be increasing the milk to 4l and removing the grana padano.
If you find yourself curious enough towards such experimentation it'd great if you were to have ceruloplasmin and total plasma copper and plasma SOD activity measured before and after that fluid dairy diet. Ideally also serum oder plasma total bicarbonate before and after.
(HCO3- should be above a putative 24mmol/L renal threshold up to about 31mmol/L basally. <20 is already detrimental but commonly ignored until blood pH drop at about <12.) -
@CrumblingCookie Unless you want to cover the testing costs, I most likely won't XD
Hans Amato did a 5 litre milk diet and he has the money to test these things, so maybe ask him about that stuff -
I lied sorry, there is little phosphatidyl choline in cows milk
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But still. Phosphatidyl choline gets converted back into choline, lipids and glycerol in the gut. In the blood stream it gets reincorporated back into a phosphatidylcholine with a lipid head depending on the lipids in the blood.
So effectively it's the same.
I am trying 1000mg of Citocholine to. Hopefully that gets incorporated into saturated phoshphatidyl choline in my blood. -
What would also be an EPIC experiment, is 20g of lecithin and 40g of cococnut oil taken at the same time
Your body being flooded with saturated phospholipids -
Nevermind. WE ARE MITOLIPIN MAXING 200 - 400MG OF SATURATED PHOSPHILIPIDYL CHOLINE A DAY -
@alfredoolivas does it get broken down in the skin tissues or blood stream? Aka, a functional topical?
Pretty sure Ray said he'd appreciate a supplement of it.
awful extreme to call it a scam by Georgi -- that crabs-in-a-bucket attitude is unfortunate.
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Nevermind. WE ARE MITOLIPIN MAXING 200 - 400MG OF SATURATED PHOSPHILIPIDYL CHOLINE A DAY
quick 180 but i'll take it glad you came around hahah
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@LetTheRedeemed Yes. In the skin it gets broken down, and retained in the skin. I am actually doing Phosphatidylcholine based fat dissolving injections right now, and when researching I remember seeing that even subcutaneous administration, lead to 99% of it being held by tissues in the injection site.
A scam was a stretch, but it is a supplement with no research behind it. None. The studies he attatched to the post about MitoLipin are all to do with unsaturated phosphatidylcholine. It is a big stretch to say that it will deliver lipids into mitochondria, because it gets broken down and reformed, in the gut, liver and even in the cell I think, into a new phosphatidylcholine composed of a different lipid.
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@alfredoolivas interesting, thanks for sharing. Always love critical batting of ideas
