Fenclonine

engineer

Looks lik maybe MCR agonism is akin to a stress response?

Appears as though metergoline is the way to go even though it mostly works on serotonin

Now the challenge is finding bulk metergoline

hwisdom

@engineer melanotan makes you black through NO stimulation btw, this is why it also gives u massive boners, prolactinogenic, not peaty, fuck melanotan all these mechanisms abt it are just speculations because "erm akshually melanin good!", didnt peter thiel like fund these popular peptides or smth idfk

hwisdom

@engineer metergoline is goated, any chinese nigga on echemi would sell it to you for around like 400$ a gram, 4mg a day for me gave me all the famous benefits of blocking serotonin at a significant rate, but if you can try getting ur hands on the brand name Liserdol product, its gonna be much easier

engineer

@hwisdom it doesnt specifically touch NO, it just stimulates melanocytes through mc1r which is normally agonized by alpha msh, and NO increases mc1r expression like you would expect in a stress state

https://grok.com/share/c2hhcmQtMw_7fd6d676-eb61-41b6-8bff-c75dc29acb22

remember, iNOS is bad and eNOS is fine

engineer

@alfredoolivas said in Fenclonine:

@engineer inshallah

I just gave mami a Ray Peat starter kit

alfredoolivas

@engineer you don’t cheap out, I like it

hwisdom

@engineer I eat out my dogs asshole

jamezb46

@engineer Maybe you would like Bupropion for this purpose. It's easily available.

hwisdom

@jamezb46 it blocks serotonin like that???

jamezb46

@hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.

alfredoolivas

This post is deleted!

wester130

@engineer extremely difficult to buy from those websites

engineer

@wester130 what exactly is extremely difficult to buy?

hwisdom

@jamezb46 said in Fenclonine:

@hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.

ok thought so, thought it was smth like metergoline