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    Fenclonine

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    • engineerE Offline
      engineer @hwisdom
      last edited by engineer

      @hwisdom it doesnt specifically touch NO, it just stimulates melanocytes through mc1r which is normally agonized by alpha msh, and NO increases mc1r expression like you would expect in a stress state

      https://grok.com/share/c2hhcmQtMw_7fd6d676-eb61-41b6-8bff-c75dc29acb22

      remember, iNOS is bad and eNOS is fine

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      • engineerE Offline
        engineer @alfredoolivas
        last edited by engineer

        @alfredoolivas said in Fenclonine:

        @engineer inshallah

        I just gave mami a Ray Peat starter kit

        20260424_145843.webp

        alfredoolivasA hwisdomH 2 Replies Last reply Reply Quote 1
        • alfredoolivasA Away
          alfredoolivas @engineer
          last edited by

          @engineer you don’t cheap out, I like it

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          • hwisdomH Online
            hwisdom @engineer
            last edited by

            @engineer I eat out my dogs asshole

            MILF
            man I love fasting

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            • jamezb46J Offline
              jamezb46 @engineer
              last edited by

              @engineer Maybe you would like Bupropion for this purpose. It's easily available.

              In time there is life but no knowledge; outside time there is knowledge but no life

              hwisdomH 1 Reply Last reply Reply Quote 0
              • hwisdomH Online
                hwisdom @jamezb46
                last edited by

                @jamezb46 it blocks serotonin like that???

                MILF
                man I love fasting

                jamezb46J 1 Reply Last reply Reply Quote 0
                • jamezb46J Offline
                  jamezb46 @hwisdom
                  last edited by

                  @hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.

                  In time there is life but no knowledge; outside time there is knowledge but no life

                  alfredoolivasA hwisdomH 2 Replies Last reply Reply Quote 0
                  • alfredoolivasA Away
                    alfredoolivas @jamezb46
                    last edited by

                    This post is deleted!
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                    • W Offline
                      wester130 @engineer
                      last edited by

                      @engineer extremely difficult to buy from those websites

                      engineerE 1 Reply Last reply Reply Quote 0
                      • engineerE Offline
                        engineer @wester130
                        last edited by engineer

                        @wester130 what exactly is extremely difficult to buy?

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                        • hwisdomH Online
                          hwisdom @jamezb46
                          last edited by

                          @jamezb46 said in Fenclonine:

                          @hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.

                          ok thought so, thought it was smth like metergoline

                          MILF
                          man I love fasting

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