Hydrogen Attenuates Allergic Inflammation by increasing oxphos/lowering glycolysis
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The paper reports that molecular hydrogen reduced allergic airway inflammation in an asthma model by shifting metabolism back from aerobic glycolysis toward mitochondrial oxidative phosphorylation. In plain terms, it suggests hydrogen may calm inflammation partly by restoring a more normal energy-production state in immune cells
What the study found
Asthmatic patients’ monocytes and allergen-challenged mice showed increased lactate and glycolytic enzyme activity, along with lower ATP production and weaker mitochondrial respiratory-chain activity
Hydrogen treatment reversed those changes in mice and reduced airway inflammationIn the study, hydrogen treatment inhibited the upregulation and nuclear translocation of HIF-1α (hypoxia-inducible factor 1-alpha) that occurs during allergic inflammation in the mouse model
helping restore oxidative phosphorylation over glycolysis -
Molecular hydrogen inhalation machines and molecular hydrogen infused water are good ways to get it. I remember seeing peat have positive things to say on it. It also increases coq10 in immune cells and likely others
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Interesting thanks for sharing.
Thats pretty big news. Everything that lowers HIF-1a lowers glycolysis, increases mitochondria, CO2, is anti-cancer etc.
So molecular hydrogen might be more peaty than I thought.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5745720/
CO2 is probably the most basic and important off switch of anaerobic glycolysis. Maybe molecular hydrogen has similar benefits.
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@user73636 sounded like a gimmick at first but its well studied theres a lot on it, decent amount from japan ,
another way to get it without a machine is buying some elemental magnesium metal sticks or ribbons (safer to avoid as fine powder tho unless stored right). can add a stick or ribbon chunk to water and it will make hydrogen bubbles (added a small amount of malic acid to speed up getting past the oxide surface and a bit more hydrogen , then rinsing after drinking. i added it without malic and it still bubbled)
https://bioenergetic.forum/topic/9291/hydrogen-dissolved-in-drinking-water-or-via-gastric-acid
i reckon 200ug hydrogen at once would be good. trying to figure out how much a 10cm 130mg ribbon would give. max water saturation you can get is 1mg - 1.5mg per L but it reacts slow and without a lot of acid it forms a black layer. i read some papers where they dipped it for a short time and it had effect still
