@Mulloch94 Perhaps you miss a fundamental step that by the time the substance leaves the system the final acetylcholine will perhaps be higher than before. Do you understand what I mean? a typical example is when you use Cypro for example you might feel terrible during it but when it comes out you will feel better due to a matter of receptor under-regulation and over-regulation. I gave a random example but it could apply to anything we introduce. I absolutely need to reactivate acetylcholinesterase or antagonize whatever is blocking the enzyme. They mention atropine scopolamine but the hospital should do it, not me!