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    Peaty migraine remedies?

    Bioenergetics Discussion
    migraine
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    • normalgirlN
      normalgirl
      last edited by

      I’m aware that Ray Peat suffered from migraines IIRC, but what could be considered a good treatment for them?

      ~normalgirl*+•.’

      SmittyS DakotaD 2 Replies Last reply Reply Quote 0
      • Hando-JinH
        Hando-Jin
        last edited by

        hey

        Someone close to me is a migraine-r. It usually begins with intestinal problems for her, which is a clue I think that it is starting with massive intestinal inflammation. A decent dose of minocycline (200mg) combined with 2mg of cyproheptadine usually knocks it out for her and spares her two days of agony.

        My mother also had migraines for years while she was going through menopause, so probably an estrogen thing there.

        I think migraines are always a metabolic problem, you just have to find out which pathway it's happening along. Ray said he got his under control just eating a carrot everyday.

        Progesterone, thyroid, lisuride, metergoline, cyproheptadine, carrots for for the fibre, cascara and anything strongly anti inflammatory like aspirin and minocycline are things you could experiment with.

        normalgirlN 1 Reply Last reply Reply Quote 0
        • SmittyS
          Smitty @normalgirl
          last edited by

          @normalgirl Are they frequent? Most bioenergetic principles reduced the frequency of mine. Have you experimented eliminating certain food groups – gluten, sulfur, salicylates, etc.? 2 aspirin tablets and a nap obliterate my migraines.

          normalgirlN 1 Reply Last reply Reply Quote 0
          • DakotaD
            Dakota @normalgirl
            last edited by

            @normalgirl I think peat has recommended both 100mg progesterone and vitamin B2 as remedies for migraines.

            latinxgokuL 1 Reply Last reply Reply Quote 0
            • latinxgokuL
              latinxgoku @Dakota
              last edited by

              @Dakota

              Riboflavin is effective for migraine prophylaxis as 400 mg/day significantly reduced migraine incidence and severity.

              https://pubmed.ncbi.nlm.nih.gov/33779525/

              DakotaD 1 Reply Last reply Reply Quote 0
              • izkrovI
                izkrov
                last edited by

                Cutting out pufas and taking progest-e stopped my migraines, haven't had one in 2 years.

                1 Reply Last reply Reply Quote 0
                • DakotaD
                  Dakota @latinxgoku
                  last edited by

                  @latinxgoku nice. The only issue is I think that might be way too high of a dose from a bioenergetic perspective.

                  SmittyS latinxgokuL 2 Replies Last reply Reply Quote 0
                  • SmittyS
                    Smitty @Dakota
                    last edited by

                    @Dakota @latinxgoku You're right, Ray said doses >10mg are allergenic.

                    1 Reply Last reply Reply Quote 0
                    • latinxgokuL
                      latinxgoku @Dakota
                      last edited by

                      @Dakota

                      It probably is, the dose was given in consideration to see optimum pharmacokinetics of riboflavin for migraine patients.

                      1 Reply Last reply Reply Quote 0
                      • anabologyA
                        anabology
                        last edited by

                        My migraines weren't fixed until I upped my sugar intake significantly and cut out all PUFAs. I started eating more eggs recently and headaches have started to creep back. Think I'm going to go back to my default diet.

                        See diet here:
                        https://longestlevers.com/anabology-top/good-foods.html
                        Use the upper menu w/ high sugar content and lower fat and it should work very well for migraines

                        anabologyA SmittyS 2 Replies Last reply Reply Quote 0
                        • anabologyA
                          anabology @anabology
                          last edited by

                          @anabology This is for prevention but treatment I throw everything at it if it happens:

                          • t3 -- higher dose than I usually tolerate
                          • 1g aspirin
                          • a lot of baking soda
                          • latte with a ton of maple syrup
                          • progesterone
                          • more calories
                          • sparkling water if thirsty
                          KrutonK Hando-JinH 2 Replies Last reply Reply Quote 0
                          • SmittyS
                            Smitty @anabology
                            last edited by

                            @anabology It's fascinating how bioindividual we all are. Due to a recent hypersensitivity to salicylates, potatoes are my primary carb source and I haven't had an increase in migraines.

                            1 Reply Last reply Reply Quote 0
                            • ahA
                              ah
                              last edited by

                              Drinking lots of coca cola and taking niacinamide and b6, to start.

                              If its bad, I noticed that taking a little bit of metergoline (any ergoline dopamine agonist/serotonin antagonist should do) can make a migraine vanish instantly
                              Makes sense considering that migraines are largely serotonin driven, particularly at 5HT2 receptors. The most powerful anti-migraine drugs are all either direct 5HT2 receptor antagonists (particularly preventatives such as pizotifen, cyproheptadine, methysergide, etc) or indirectly via 5HT1 agonism, such as with triptans. Anyway, its well established even in mainstream medicine that serotonin drives migraines: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451809/pdf/10194_2001_Article_8.pdf

                              I suspect ergolines are most effective, but like I mentioned, anything that antagonises serotonin should work, cypro, pizotifen, other antihistamines that antagonise serotonin, mayyybe famotidine if youre in a pinch, not sure about that one
                              Of course, any problem involving serotonin starts in the gut, where most serotonin is produced and serotonergicity driven by endotoxin. So a diet that absorbs in the stomach and upper third of the intestine is important. And the usual remedies, carrot salad, oregano oil, antibiotics if you absolutely need it.

                              normalgirlN 1 Reply Last reply Reply Quote 0
                              • KrutonK
                                Kruton
                                last edited by

                                BAKING SODA!!

                                Seriously the biggest contributor to relieving my lifelong migraines was this, food grade baking soda. I always throw everything i have at it now. The concoction is baking soda, progesterone, ginkgo bilobo, salt, thyroid, creatine, aspirin, caffeine, and ice cream. I have completely remedied myself with this. They use to get so bad i could only huddle up in the middle of my bed with my eyes closed, couldn’t move, paralyzed in the pain. High doses of ibuprofen seemed to be the only relief and after taking it i’d fall asleep. Now i don’t have to take that detrimental ‘medicine’ to help my migraines.

                                Baking Soda and/or Salt
                                Progesterone
                                Aspirin
                                Creatine
                                Thyroid
                                Ginko Bilobo
                                Caffiene
                                Icecream

                                Sometimes kratom but not needed now if I have the above. Migraines cured.

                                ps- i have recently added cypro from idealabs to my stack and it is also supposed to help with migraines, i haven’t had another since but when/if i do i’ll try cypro for it to see how it fares. I gave my mother some after she developed one and it seemed to help along with magnesium glycinate as that is wat i had on hand.

                                1 Reply Last reply Reply Quote 0
                                • KrutonK
                                  Kruton @anabology
                                  last edited by

                                  @anabology yes same, thank you for helping me with the suggestions previously. I don’t really get them much anymore.

                                  1 Reply Last reply Reply Quote 0
                                  • BioSB
                                    BioS
                                    last edited by

                                    Serotonin blockers were used for migraine when nothing else was available. Methysergide was the best anti-migrane medication but it was withdrawn because it caused retroperitoneal fibrosis.

                                    In some countries, pizotifen and cyproheptadine are used for migraine prevention.

                                    Anything that lowers serotonin will prevent a migraine. GABA agonists like progesterone can also be used to abort an incoming one

                                    normalgirlN 1 Reply Last reply Reply Quote 0
                                    • rayjeetR
                                      rayjeet
                                      last edited by

                                      eat sugar

                                      1 Reply Last reply Reply Quote 0
                                      • Hando-JinH
                                        Hando-Jin @anabology
                                        last edited by

                                        @anabology a big dose of t3 can stop a lot of bad things. I've gotten rid of extremely bad internal hemorrhoids using decent amounts of t3 for a few days. Worth it even though it causes fatigue.

                                        1 Reply Last reply Reply Quote 0
                                        • normalgirlN
                                          normalgirl @Hando-Jin
                                          last edited by

                                          @Hando-Jin I've confirmed it to not be an estrogen problem since they don't have any marked frequency around my menstrual cycle or with any hormone changes. I am currently taking tyronene which has helped some but hasn't completely gotten rid of them. There's more work to be done

                                          ~normalgirl*+•.’

                                          1 Reply Last reply Reply Quote 0
                                          • normalgirlN
                                            normalgirl @Smitty
                                            last edited by

                                            @Smitty Ironically they're resistant to aspirin, which is why I started getting concerned. For around 2 months they were happening almost every day

                                            ~normalgirl*+•.’

                                            1 Reply Last reply Reply Quote 0
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