Peaty migraine remedies?
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Riboflavin is effective for migraine prophylaxis as 400 mg/day significantly reduced migraine incidence and severity.
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Cutting out pufas and taking progest-e stopped my migraines, haven't had one in 2 years.
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@latinxgoku nice. The only issue is I think that might be way too high of a dose from a bioenergetic perspective.
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@Dakota @latinxgoku You're right, Ray said doses >10mg are allergenic.
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It probably is, the dose was given in consideration to see optimum pharmacokinetics of riboflavin for migraine patients.
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My migraines weren't fixed until I upped my sugar intake significantly and cut out all PUFAs. I started eating more eggs recently and headaches have started to creep back. Think I'm going to go back to my default diet.
See diet here:
https://longestlevers.com/anabology-top/good-foods.html
Use the upper menu w/ high sugar content and lower fat and it should work very well for migraines -
@anabology This is for prevention but treatment I throw everything at it if it happens:
- t3 -- higher dose than I usually tolerate
- 1g aspirin
- a lot of baking soda
- latte with a ton of maple syrup
- progesterone
- more calories
- sparkling water if thirsty
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@anabology It's fascinating how bioindividual we all are. Due to a recent hypersensitivity to salicylates, potatoes are my primary carb source and I haven't had an increase in migraines.
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Drinking lots of coca cola and taking niacinamide and b6, to start.
If its bad, I noticed that taking a little bit of metergoline (any ergoline dopamine agonist/serotonin antagonist should do) can make a migraine vanish instantly
Makes sense considering that migraines are largely serotonin driven, particularly at 5HT2 receptors. The most powerful anti-migraine drugs are all either direct 5HT2 receptor antagonists (particularly preventatives such as pizotifen, cyproheptadine, methysergide, etc) or indirectly via 5HT1 agonism, such as with triptans. Anyway, its well established even in mainstream medicine that serotonin drives migraines: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451809/pdf/10194_2001_Article_8.pdfI suspect ergolines are most effective, but like I mentioned, anything that antagonises serotonin should work, cypro, pizotifen, other antihistamines that antagonise serotonin, mayyybe famotidine if youre in a pinch, not sure about that one
Of course, any problem involving serotonin starts in the gut, where most serotonin is produced and serotonergicity driven by endotoxin. So a diet that absorbs in the stomach and upper third of the intestine is important. And the usual remedies, carrot salad, oregano oil, antibiotics if you absolutely need it. -
BAKING SODA!!
Seriously the biggest contributor to relieving my lifelong migraines was this, food grade baking soda. I always throw everything i have at it now. The concoction is baking soda, progesterone, ginkgo bilobo, salt, thyroid, creatine, aspirin, caffeine, and ice cream. I have completely remedied myself with this. They use to get so bad i could only huddle up in the middle of my bed with my eyes closed, couldn’t move, paralyzed in the pain. High doses of ibuprofen seemed to be the only relief and after taking it i’d fall asleep. Now i don’t have to take that detrimental ‘medicine’ to help my migraines.
Baking Soda and/or Salt
Progesterone
Aspirin
Creatine
Thyroid
Ginko Bilobo
Caffiene
IcecreamSometimes kratom but not needed now if I have the above. Migraines cured.
ps- i have recently added cypro from idealabs to my stack and it is also supposed to help with migraines, i haven’t had another since but when/if i do i’ll try cypro for it to see how it fares. I gave my mother some after she developed one and it seemed to help along with magnesium glycinate as that is wat i had on hand.
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@anabology yes same, thank you for helping me with the suggestions previously. I don’t really get them much anymore.
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Serotonin blockers were used for migraine when nothing else was available. Methysergide was the best anti-migrane medication but it was withdrawn because it caused retroperitoneal fibrosis.
In some countries, pizotifen and cyproheptadine are used for migraine prevention.
Anything that lowers serotonin will prevent a migraine. GABA agonists like progesterone can also be used to abort an incoming one
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eat sugar
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@anabology a big dose of t3 can stop a lot of bad things. I've gotten rid of extremely bad internal hemorrhoids using decent amounts of t3 for a few days. Worth it even though it causes fatigue.
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@Hando-Jin I've confirmed it to not be an estrogen problem since they don't have any marked frequency around my menstrual cycle or with any hormone changes. I am currently taking tyronene which has helped some but hasn't completely gotten rid of them. There's more work to be done
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@Smitty Ironically they're resistant to aspirin, which is why I started getting concerned. For around 2 months they were happening almost every day
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Hope this helps!
https://constantinek.substack.com/p/migraines-and-headaches -
@BioS Interesting, I was actually prescribed venlafaxine which does the exact opposite, and it was objectively the time when I felt the absolute worst. I don't know how this stuff is prescribed regularly to anyone. I had also tried valproate which is increases GABA neurotransmission, but that didn't do much for me. I'll take a look at methysergide!
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@ah Triptans and 5HT2 receptor antagonists didn't even work for me, but I find some relief with DPH. Not sure if you're familiar with CGRP receptor antagonists, but only one or two of those have worked to give me some relief.
