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    Is there more to coffee than caffeine?

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    • R
      Ray Peat Fanboy
      last edited by Ray Peat Fanboy

      What would you say are the health benefits of choosing coffee instead of caffeine pills?

      Or perhaps might aswell both drink coffee and take caffeine pills. The way I see it is that caffeine pills might be preferable when higher dosages of caffeine are needed to reverse fatty liver for example (easier to measure caffeine dosage with pills)

      CO3C cs3000C 2 Replies Last reply Reply Quote 0
      • LinDaiyuL
        LinDaiyu
        last edited by

        magnesium innit

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        • BioEclecticB
          BioEclectic
          last edited by BioEclectic

          As per the following article coffee contains a thousand different substances:

          https://web.archive.org/web/20200814175208/https://www.health.harvard.edu/healthbeat/what-is-it-about-coffee

          I linked the archived version because the current site edited out a lot of interesting info.

          Take their so called cholesterol info with a grain of salt since it's likely based upon establishment "science".

          I've been meaning to research two of the cholesterols a little further; cafestol and kahweol. The funny part is a standard paper coffee filter will allegedly filter them out.

          Similar to eating the whole orange vs Vitamin C pills there's possibly a balance achieved by drinking coffee over simple caffeine. It'll also depend on your personal tolerance but i find i can drink a lot more coffee symptom free by adding a tiny bit of baking soda.

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          • BioEclecticB
            BioEclectic @BioEclectic
            last edited by BioEclectic

            This post is deleted!
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            • CO3C
              CO3 @Ray Peat Fanboy
              last edited by

              @Ray-Peat-Fanboy Coffee contains a lot more than just caffeine. So the answer is yes.

              Master Broth Recipe: https://twitter.com/thesquattingman/status/1737526599023526043 / https://recipeats.org/master-broth/

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              • cs3000C
                cs3000 @Ray Peat Fanboy
                last edited by cs3000

                @Ray-Peat-Fanboy yeah coffee also high in chlorogenic acids , which apparently increases neurogenesis (through turning into caffeic acid in the body). i think ~30% - 60% gets metabolised and ~30% of that goes to caffeic acid
                and some goes to benzoic acid (which is not good / harmful in higher amounts (e.g i wouldnt like 100mg consecutively) but at low amounts is a mild uncoupler for more heat production by mitochondria https://hal.science/hal-00478797/document. is similar to aspirin).
                also the caffeic acid + quinic acid are mao-b inhibitors, quinic mild
                https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838583/

                Upon reaching the colon, chlorogenic acids are hydrolyzed to caffeic acid and quinic acid that are further metabolized through common metabolic pathways mediated by the intestinal microflora. Quinic acid is converted to benzoic acid, which can be further metabolized in the liver by conjugation reaction with glycine to produce hippuric acid. Gonthier et al. (2003)
                reported that approximately 60% of an ingested dose of chlorogenic acid is recovered as metabolites in the urine of rats, with hippuric acid being the predominant metabolite accounting for 36.5% of the ingested dose.
                The available studies in humans also indicate that approximately 70% of an ingested dose of chlorogenic acid is transported to the colon intact

                quinic acid, chlorogenic acid are selective MAO-B inhibitors (quinic acid is mild) in vitro and in vivo also reversed the MAO-A inhibition caused by aluminium (quinic acid neuroprotective in aluminium toxicity but at high dose idk how significant for doses gained through coffee)

                "world," as a source of new perceptions
                more https://substack.com/@cs3001

                "Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"

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