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    Glucose loading cures everything?

    Bioenergetic Development
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    • S
      S.Holmes @evan.hinkle
      last edited by

      @evan-hinkle Excellent! I was hoping to use it more in place of sucrose and it sounds like you're doing that as well, and with positive results!

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      • yerragY
        yerrag @S.Holmes
        last edited by

        @S-Holmes said in Glucose loading cures everything?:

        @S-Holmes It makes sense to me. If your brain is well fed, it can stop signalling the body to release/make more fuel, which can't get into the brain anyhow (due to stress and injuries). So the glucose stops the cascade by nourishing the brain, bypassing the digestive process and going directly to the brain where it's needed.

        How is the digestive process bypassed? I fail to see the logic. One way the digestive process is bypassed is by IV feeding. But I don't know if this is what you mean.

        Temporal thinking is the faculty that’s
        engaged by an enriched environment, but it’s
        wrong to call it “thinking,” because it’s simply
        the way organisms exist... - Ray Peat Nov 2017 Newsletter

        S InsomniacI 2 Replies Last reply Reply Quote 0
        • S
          S.Holmes @yerrag
          last edited by

          @yerrag This is the best I can do for now.
          1000007456.jpg

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          • S
            S.Holmes @S.Holmes
            last edited by

            It bypasses the process needed to break food down into glucose, gluconeogenesis is the term I believe.

            yerragY 1 Reply Last reply Reply Quote 0
            • yerragY
              yerrag @Insomniac
              last edited by

              @Insomniac

              Stephens call his glucose ahah moment an inspiration from God.

              If he were more honest about it, he would reference Ray Peat as well as Prof. Gershom Zajicek ( who talked about using glucose to restore the beta cells of the pancreas to restore the production of insulin).

              But he may just be simply unaware others have thought of this idea. Stephens comes from a neuropsychological background, which is not exactly blessed with sound science given the scores of patients they have sent to hopelessness and despair and suicide.

              But he was astute enough to notice how many patients with concussive injuries could benefit from glucose loading to overcome brain injuries.

              But he attributes all of the brain's problems with lack of sugar to physical injuries, as that is the limit or scope of his clinical practice being a neuropsychologist. But he fails to consider that there has been for a long time a concerted effort by the establishment to blame all of society's health problems on sugar. Seconded by armchair YouTube experts that amplify this line. So a lot more damage on our brains has been done by conditioning us to hate sugar.

              Temporal thinking is the faculty that’s
              engaged by an enriched environment, but it’s
              wrong to call it “thinking,” because it’s simply
              the way organisms exist... - Ray Peat Nov 2017 Newsletter

              B 1 Reply Last reply Reply Quote 0
              • yerragY
                yerrag @S.Holmes
                last edited by yerrag

                @S-Holmes said in Glucose loading cures everything?:

                I haven't quite figured out how or why the brain downregulates sugar usage following every stress (any kind of stress). Stress seems to trigger lipolysis (vs glycolysis) and the damage is CUMULATIVE. Is this why stress kills? I've ordered his latest book. Hopefully he addresses this in depth.

                I don't agree with framing low sugar usage by the brain to be caused by the brain downregulating sugar usage. The brain can keep sending signals for sugar to be delivered to it by blood, as well as oxygen, but it can only direct but the cardiovascular system is the one that fulfills that directive, subject to its state of health. If the tissues cannot absorb glucose because say potassium is deficient, there is nothing the brain can do. Likewise with oxygen, if CO2 is deficient in blood, hemoglobin will not release oxygen to the brain cells.

                What specific stress are you referring to that triggers lipolysis? That presupposes stress is needed to trigger lipolysis. But what if lipolysis is just a regular process to release fats from fat stores to be used by fatty-acid oxidation as part of the body's ability to use different energy pathways (I.e. sugar oxidation and fat oxidation) to optimize energy production and conserve sugar for use by the brain?

                In fact, one thing insulin does is to inhibit lipolysis. Which means that when blood sugar levels are stable and normal, and insulin is not produced, lipolysis goes on as a normal process in the body.

                And this may be the reason why people with good and stable blood sugar levels do not get overweight nor obese, as they are constantly using up their fat stores for energy, and their fat stores do not accumulate.

                Temporal thinking is the faculty that’s
                engaged by an enriched environment, but it’s
                wrong to call it “thinking,” because it’s simply
                the way organisms exist... - Ray Peat Nov 2017 Newsletter

                S 2 Replies Last reply Reply Quote 0
                • yerragY
                  yerrag @S.Holmes
                  last edited by

                  @S-Holmes

                  Gluconeogenesis isn't used in the digestive process.

                  Complex sugars are broken down to simple sugars down to becoming glucose, which is absorbed by the small intestine, and assimilated into blood as blood sugar.

                  Gluconeogenesis is when protein is broken down into glucogenic amino acids, which are further broken down to be used to make glucose. I believe the liver, and to some extent, the kidneys, does this.

                  Temporal thinking is the faculty that’s
                  engaged by an enriched environment, but it’s
                  wrong to call it “thinking,” because it’s simply
                  the way organisms exist... - Ray Peat Nov 2017 Newsletter

                  1 Reply Last reply Reply Quote 0
                  • InsomniacI
                    Insomniac @yerrag
                    last edited by

                    This post is deleted!
                    E yerragY 2 Replies Last reply Reply Quote 0
                    • P
                      Peatful
                      last edited by

                      Just visited the RPF

                      So bizarre

                      The questions in this thread have again mostly been discussed by Ray
                      If not directly
                      Meaning not told exactly “how to do it”
                      This is where we are to perceive think act

                      From my personal experience
                      And I healed from extremely poor health to now the greatest health I’ve ever had
                      Sugar was absolutely foundational
                      A foundation is what we build upon

                      But
                      Im here to say
                      As I said over there

                      Stress hormones desensitize the insulin receptor
                      From birth to now, most of us have had some sort of stress that is shaped our experience of our health
                      With chronic stress comes many things all of which desensitizes the insulin receptor

                      When you reintroduce sugar your body is essentially already in an insulin resistant state
                      The stress hormones flooding your system overtime have desensitized the insulin receptor so insulin cannot drive glucose into the cell anymore….

                      I point this out because the more I used this wonderful “nutrient”
                      The more I was able to handle it and really reap the benefits of using it not only in relatively large quantities- my ability to utilize it as a therapeutic tool only got better and better
                      But the beginning was rough
                      Really rough
                      Due to my stressed metabolic state

                      Anyway
                      Just stunned that Ray isn’t understood nor acknowledged on his own forum
                      I grieve that shit

                      Please listen to him here
                      He addresses a lot iirc

                      A prophet
                      A genius
                      And a friend

                      Youtube Video

                      One act of obedience is better than one hundred sermons.

                      -DB

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                      • B
                        bot-mod @Peatful
                        last edited by

                        I was in awe having a scroll of it this morning. Their power struggles and appeals to spertise occasionally gets a bit shakespearian. Someone could probably write an entertaining novel about RPF.

                        Aside from that Ms Peatful. I know the feelings. Beside and probably not distinct from the science.

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                        • B
                          bot-mod @yerrag
                          last edited by

                          All a bit strange hey Mr Yerrag. I find myself affirm to your observation.

                          Meanwhile, I get the feeling there's something in this. I'll have to read around quite a lot, enjoy surrounding conversation and sleep well I guess. All I can do right now is speculate. That the fructose is unwelcome to him for myocardial reasons and the glucose still benefits for structural and therefore metabolic reasons. Probably not without personal consequence. But at least it begs some questions.

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                          • S
                            S.Holmes @Peatful
                            last edited by

                            @Peatful Could you expound on "rough"? I had a very strange burning pain from my neck to the bottom of my ribs yesterday (right side). I put an aspirin under my tongue and took a homeopathic remedy to treat stroke, just in case. It lasted about 15 minutes and then I was fine.

                            If not for Dr.Peat I wouldn't have given the sucrose protocol a second look. I think he saved my life, but I still have lingering issues, and weight gain which is difficult because I was very thin my entire life. So I'm willing to try anything to feel better. I've been on Nathan Hatch's protocol for a few months, and it was helpful but still didn't quite get me "there." (I still use some of the things he suggests.)

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                            • S
                              S.Holmes @yerrag
                              last edited by

                              @yerrag Right, I was referring to fuel being obtained from protein or fat. Simple sugars are absorbed in the stomach, not the intestines. That's what I meant by bypassing the digestive process.

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                              • E
                                evan.hinkle @Insomniac
                                last edited by

                                @Insomniac but here’s the kicker, my blood glucose levels are lower. Where I was spiking to 150 after a meal I’m now spiking to 125. Every time I check my blood glucose it’s 20-30 points lower than my typical readings without dextrose.

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                                • P
                                  Peatful @S.Holmes
                                  last edited by

                                  @S-Holmes said in Glucose loading cures everything?:

                                  @Peatful Could you expound on "rough"? I had a very strange burning pain from my neck to the bottom of my ribs yesterday (right side). I put an aspirin under my tongue and took a homeopathic remedy to treat stroke, just in case. It lasted about 15 minutes and then I was fine.

                                  If not for Dr.Peat I wouldn't have given the sucrose protocol a second look. I think he saved my life, but I still have lingering issues, and weight gain which is difficult because I was very thin my entire life. So I'm willing to try anything to feel better. I've been on Nathan Hatch's protocol for a few months, and it was helpful but still didn't quite get me "there." (I still use some of the things he suggests.)

                                  Yes
                                  I had odd symptoms
                                  Troubling ones
                                  But transient

                                  I had significant weight gain
                                  But
                                  That was not about the sugar or the foods
                                  The weight gain reflected the damage already done in my body

                                  It was so much fluid
                                  And
                                  As said above
                                  With any history of restriction or stress
                                  You will start with your cells unable to get the sugar in
                                  But it gets better
                                  Your body has to relearn

                                  Maybe this will help give you an idea?

                                  Im around today
                                  Jyst need to run now

                                  Thx

                                  https://raypeatforum.com/community/threads/reintroducing-peaty-eating-after-very-low-carb-low-calorie.50945/

                                  One act of obedience is better than one hundred sermons.

                                  -DB

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                                  • S
                                    S.Holmes @yerrag
                                    last edited by

                                    @yerrag Well, the doctor admits that some of the protocol is based on theory...such as how quickly and preferentially the glucose appears to make it's way to the brain, within a couple of minutes! I believe that was the theory he said he would need spinal tap volunteers for. Who would sign up for that??? Theories, in my opinion, should be put to the test. He has been testing it out for a while now, with amazing successes. I'm just doing my part.

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                                    • S
                                      S.Holmes @evan.hinkle
                                      last edited by

                                      This post is deleted!
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                                      • S
                                        S.Holmes @evan.hinkle
                                        last edited by

                                        @evan-hinkle said in Glucose loading cures everything?:

                                        @Insomniac but here’s the kicker, my blood glucose levels are lower. Where I was spiking to 150 after a meal I’m now spiking to 125. Every time I check my blood glucose it’s 20-30 points lower than my typical readings without dextrose.

                                        THIS!!!

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                                        • B
                                          bot-mod @evan.hinkle
                                          last edited by

                                          I'd ask for your urinary volumes throughout the day but I'm not going to push my luck. Or be that weird.

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                                          • S
                                            S.Holmes @Peatful
                                            last edited by

                                            @Peatful Yes, very helpful, thank you.

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