Seborrheic Dermatitis (SD) cured by Topical Caprylic Acid (C8:0)Triglycerides
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@jamezb46 said in Seborrheic Dermatitis (SD) cured by Topical Caprylic Acid (C8:0)Triglycerides:
That’s awesome to hear. Did you recommend it based on this post?
Yes. They had both been using regular coconut oil. Switching to c8 made a world of difference.
"You're changing your past every time you learn something because you become a different organism" Ray Peat
"Everything is changing thru time, whether it's a word, organism, thing. The world around it changes, and so its relationships change"Ray Peat
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Wonderful. Glad to see my solution seems to be of general utility.
Of additional interest is the androgenicity of caprylic acid. Perhaps that is another mechanism by which it opposes the inflammatory response that is SD. Namely, by opposing estrogen.
I’m currently researching p5p, the active form of vitamin b6 for this skin disorder as well. I’ll report back in a few months. It may be that SD is really a micronutrient deficiency, of some combination of zinc, b6, selenium, etc.
Since people in the RP community don’t eat a lot of PUFA, their metabolic rate is higher and thus the need for these micronutrients, as demonstrated in the PUFA-deficient mice who developed scaly skin on their paws.
The fact that one study gave them b6 and saw no improvement doesn’t really show much, since they didn’t control for other micronutrients such as those above mentioned.
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09.21.20 The True Natrue of a Virus, September 21, 2020 [897179593]
“…Interesting. Wow. Wow, wow, wow. Let me do this first. Does Dr. Peat have any advice for an ongoing seborrheic dermatitis? I'm worried that it's kind of an autoimmune response from old vaccines. I would be interested to know what Dr. Peat thinks about homeopathic medicine as well in general.I haven't had any experience with homeopathics for that, but vitamin D and the calcium phosphate ratio in the diet are, I think, the first things that should be explored. Vitamin D has many effects on the skin.”
“All things are poison and nothing is without poison; only the dose makes a thing not a poison.” - Paracelsus (c. 1493–1541)
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Thanks for the information, especially since it is a direct response from Dr. Peat.
There are a number of threads on the RP forum about some ( I think it was Charlie, among others, a long time ago) getting relief from dry skin with b6. Some, however, did not find relief with the b6 supplementation.
I think the calcium/phosphate and vitamin d work systemically, and decrease inflammation/improve metabolism in the whole organism. For example, dialing in the calcium/phosphate ratio would decrease PTH, and thus allow for t3 to increase, thus improving metabolism across the whole organism.
Vitamin D is also known to be weakly androgenic (and thus oppositional to estogen), which is potentially a shared MOA with C8:0.
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@jamezb46 Everytime I've tried to apply topical coconut oil or MCT oil, I get worse acne for several days at the application site -- has your research led you to any thoughts on that?
Many thanks
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Yes,
Since it is known that caprylic acid is androgenic, it might be that the caprylic acid is acting locally as an androgen-mimetic thus giving you acne.
You can read about how it - "promotes the proliferation of prostate cancer" (I don't think androgens cause or worsen prostate cancer - in fact testosterone injections into prostate cancer cells cause the cancer to regress) - which really means that it is trophic to the prostate and thus either acts as an androgen-mimetic or enhances the activity of endogenous androgens.
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@LetTheRedeemed said in Seborrheic Dermatitis (SD) cured by Topical Caprylic Acid (C8:0)Triglycerides:
@jamezb46 Everytime I've tried to apply topical coconut oil or MCT oil, I get worse acne for several days at the application site -- has your research led you to any thoughts on that?
Many thanks
Is it possible that this treatment is oil-based and thus able to penetrate thru sebum in any of the skin layers that were impenetrable with water-based treatments you've used before? And because it is an effective antimicrobial, it is able to attack effectively the embedded microbe causing the acne, and the seemingly worsening acne is pus coming out from a resolved focal infection?
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Wow, interesting. Thanks a lot guys! I may push thru it topically for a week and see how it goes.
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any updates here on long term success? I started today with the C8 oil lets see how it goes…
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Do you have any "before" pictures? I want to compare my skin.
MCT oil worked for my face and hairline for a while, then stopped working randomly. It used to heal, now only serves as a moisturizer.
I was using C8/C10 combo MCT though. Wondering if C8 only might be worth the buy. -
@Mr-X dang I forgot *:D
I definitely have clearer/worsened skin depending on when I have good metabolism vs stress.
