Thyroid Log
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@GreekDemiGod have you ever tried NDT? Just curious, after reading Broda Barnes and some other book which references Barnes a lot, his patients seem to favor NDT over synthetic. I'm myself in the process of upping my synthetic T3/T4 to 30mcg/100mcg Wondering if NDT is something to potentially consider.
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A very nice benefit that I get from thyroid is improved blood sugar regulation. I do much better when in-between meals, I don’t get hungry that often, and if I do get it, I am still able to function great, and not see a crash in energy levels.
@Jonk I tried NDT once from Idealabs, I did ok on it, but the benefits were not that significant. Perhaps I should have increased the dose.
I’m now happy with Novotyral and see no reason to switch. -
Increasing protein intake over 150g/ day seems to cause lower temps, cold feet, even on over 400g of carbs / day, so a 2:1, or close to 3:1 ratio.
I tried eating a 50:30:20 macro split of carbs/ fats/ protein, at 3000 calories, and I felt worse increasing protein.
I will try 60:25:15 next. -
My health is getting better, Novothyral has allowed time to (partially or more) tolerate and enjoy a wider variety of foods. I handle dairy better (hard cheese, kefir, overnight oats. Some veggies, like raw cucumber and tomatoes.
Been craving cucumbers a lot last couple of day, feels like a need for hydration/ electrolytes.I also feel like I’m at a point where I can build my microbiome diversity due to improved food tolerances.
I now have relatively stable energy levels from day to day, I can function normally, stay focused on mental tasks at my job for a couple of hours per day. 2-4 bowel movements per day.
What I still struggle with is the permanent bloating, stuffed nose and low libido. I reckon that fixing that will be the last step towards healing. No matter how regular I am with my bowel movements. The bloating issue doesn’t budge. I think that it’s an issue of microbiome, fermentation in the intestine. Hopefully it will improve with time.
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@GreekDemiGod
Maybe you are fructose intolerant to some degree
Too much sugar or any fiber does bloat me
Only coke seems magical without side effects
I saw a video of a 90 year old woman with a sharp mind and a bit obese that said the most important thing to follow for a healthy life is to wear more clothes to prevent being cold
In my experience this is true, when I am bloated or have constipation, staying below the blanket doing retaining CO2 and warming up solves it
The heat from the summer is different, it doesn't help, it causes the opposite effect for me in terms of digestion if I overheat -
@Androsclerozat I reduced the agave syrup and stopped eating dried dates, and I no longer have cramps. That doesn’t solve all my problems of course, but my gut feels calmer.
So it looks like fruits with high fructose: glucose ratio can be problematic for me, in large quantities. -
@TexugoDoMel said in Thyroid Log:
Iodine is very important but remember that iodine displaces bromide and fluoride and can cause unpleasant symptoms precisely because of this. It's a good idea to adjust the amount of selenium too, as there's a good chance you'll feel unwell when supplementing with iodine if you're deficient in selenium.
What about this very valuable statement!?
You won't recover if you listen to mainstream fear for iodine phoby. -
I've been continually taking thyroid since April 2024, so more than 1 year without a break.
In the last 6 months or so, I've settled on using Novothyral, containing both T3 and T4: 100 - 125 mcg daily (more in the winter), and 20-25 mcg T4.I've felt ok for a while, had decent energy in my day-to-day life and in the gym. But lately, I started feeling really flat emotionally, lacking joy, so I figured it must be the high amounts of T4 building up and turning into rT3.
Here are my blood tests, worse than expected. TSH is suppressed, which I expected, but Free T4 is also quite low.
ChatGpt reasoning:
*Thyroid Blood Test Interpretation:
TSH: 0.0535 (Low)
This is suppressed, suggesting your brain is sensing enough (or too much) thyroid hormone. This is expected when you're on T3, as it suppresses TSH more aggressively than T4.Free T4: 0.72 (Low-normal)
This is at the bottom of the reference range. For someone on 100 mcg of T4, this is a bit unexpectedly low, unless you're under-converting or clearing it rapidly.Free T3: 2.73 (Mid-range)
This is adequate, and likely a direct result of your 20 mcg T3 dose, which is a moderately high replacement dose. It's keeping your FT3 in a solid range despite the low FT4.Yes — taking T4 (levothyroxine) with food can significantly impair its absorption, and that could absolutely explain your low-normal free T4, even on a 100 mcg dose.
Here's the no-BS breakdown:
Levothyroxine Absorption Facts:
Bioavailability drops by ~40–80% when taken with food.Coffee, calcium, iron, magnesium, fiber, and even some fruits (like papaya) interfere.
It’s best absorbed on an empty stomach, ideally 30–60 minutes before food.
So yes, if you're taking T4 with or shortly before/after food, you’re likely underdosing yourself unintentionally — even if you're swallowing a full 100 mcg.
Your Case:
Free T4 at 0.72 ng/dL (barely in range) = classic sign of poor absorption or competition for uptake.Your T3 is fine (you’re taking it directly), so the T3 value isn’t affected.
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@GreekDemiGod said in Thyroid Log:
I've felt ok for a while, had decent energy in my day-to-day life and in the gym. But lately, I started feeling really flat emotionally, lacking joy, so I figured it must be ...
When taking a supplement T3 and T4 you don't bring the required nutrients for deiodinase enzymes: Mg I Zn Se.
80% people are lacking Mg and vit D3.
Please, don't tell me you're ok because you take a supplement (Mg) and live under sunshine ... It won't solve the unbalance ... -
@LucH yo, MG you mean magnesium? How Can a person have not enough VD if she live under the sun?
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@random said in Thyroid Log:
How Can a person have not enough VD if she live under the sun?
You didn't put the right question but exactly did what I warned you not to do:
No matter if you catch the right amount of vitamin D or already take one of the supplement. You didn't match where the main problem was: The thyroid doesn't receive what it needs.
I repeat: your deiodinase enzymes are not well supplied with useful nutrients. If so, the thyroid gland can't function well.
Now, try to find by yourself what you need because you're not going to listen to what I would suggest. Why? Not mainstream opinion. -
As I don't want to play the cat and the mouse, here is a clue.
Why a lack of functional deiodinase enzyme interferes with metabolism.
Deiodinase enzymes are involved in development, growth, and metabolic processes. They are represented by D1 D2 and D3. D3 because of 3 molecules of iodine.
Deiodinases are not only essential in controlling local thyroid hormone action during development, but also for normal function of adult tissues.
Deiodinases control local cellular and systemic thyroid hormone availability.
If there is a deficit of supply in Mg Zn I Fe and Zn, an insufficient amount should occasion negative effects on the DIOs expression and activity.
DIO: deiodinase enzyme.
The deiodinase enzymes are involved in activation and inactivation of thyroid hormones (THs).*) Deiodinases control local cellular and systemic thyroid hormone availability
https://doi.org/10.1016/j.freeradbiomed.2022.09.024
Thyroid and deiodinase function depends on supply of the trace elements iodine, selenium and iron. *) Deiodinases and the Three Types of Thyroid Hormone Deiodination Reactions
doi: 10.3803/EnM.2021.1198
Thyroid hormone (TH) signaling is strictly regulated by iodothyronine deiodinase activity, which both preserves the circulating levels of the biologically active triiodothyronine (T3) and regulates TH homeostasis at the local level, in a cell- and time-dependent manner. Three deiodinases have been identified—namely iodothyronine deiodinase 1 (DIO1 – 2 and 3).
Deiodinase activity at the tissue level permits cell-targeted fine regulation of TH homeostasis, mediating the activation (DIO1 and DIO2) and inactivation (DIO3) of THs. Deiodinase homeostasis is the driving force that leads T3-target cells towards customized TH signaling, which takes into account both the hormonal circulating levels and the tissue-specific response.
*) Type 3 deiodinase and consumptive hypothyroidism: a common mechanism for a rare disease
https://doi.org/10.3389/fendo.2013.00115
Type 1 and type 2 deiodinase (D1 and D2) convert T4 into T3 whereas D3 degrades T4 and T3 into inactive metabolites and is thus the major physiological TH inactivator. The hypothalamic-pituitary-thyroid axis maintains circulating TH levels constant, while the deiodinases tissue-specifically regulate intracellular thyroid status by controlling TH action in a precise spatio-temporal fashion. -
@LucH said in Thyroid Log:
@random said in Thyroid Log:
How Can a person have not enough VD if she live under the sun?
You didn't put the right question but exactly did what I warned you not to do:
No matter if you catch the right amount of vitamin D or already take one of the supplement. You didn't match where the main problem was: The thyroid doesn't receive what it needs.
I repeat: your deiodinase enzymes are not well supplied with useful nutrients. If so, the thyroid gland can't function well.
Now, try to find by yourself what you need because you're not going to listen to what I would suggest. Why? Not mainstream opinion.That's adequate question to what you Said, stop capping. What warning? I dont act according to your warning anyway.
What are you yapping about? I didnt write that i would discard your suggestions because it goes againts mainstream opinion, you sound delusional and/or paranoïd, or potentially none of them but you enjoy acting as it is you vs others and you think its epic, when its not at all, its lame.
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@random said in Thyroid Log:
you sound delusional and/or paranoïd, or potentially none of them but you enjoy acting as it is you vs others and you think its epic, when its not at all, its lame.
OK. Peace and love. Bye.
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@GreekDemiGod I guess having a reverse t3 tested would be even more helpful.
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Last couple of days, I’ve been taking my pill of Novothyral very early in the morning, several hours before first meal of the day.
I’ve decided to stay on a stable dose and not varying doses from day to day.
And I’m seeing again a big increase in energy levels and vitality. It’s clear that T4 absorption is significantly increased when taken on empty stomach.
