Chris Masterjohn: Salicylates are Toxic
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At the 13:00 mark of the following video, Chris claims that salicylates block energy production in the mitochondria and can deplete glycine, which the body uses to rid itself of the salicylic acid.
I wonder how Chris and someone like like Haidut can come to opposite conclusions about aspirin. To those who regularly browse pubmed and the litetature, have you come across evidence supporting Chris's claims? I'm not a regular aspirin user but I take it roughly twice a month when I'm feeling sluggish and usually feel a substantial energy boost from it.
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@Sitaruim - Silly me, I think this is yet another reason to get more glycine in your diet and not a reason to avoid salicyaltes.
NutritionFacts.org has a nice video about salicylates in foods and spices and how they are assoicated with lower incidence of cancers. The video has hotlinks to the studies it refers to in the video.
https://nutritionfacts.org/video/plants-with-aspirin-aspirations/
My thinking is that if aspirin is costing pension systems $, then it has got to be healthy of people like me. It is good to learn that aspirin, which is currently cheap and readily available, is at the top of their list.
Aspirin seen costing pensions $100 billion as lifespans increase (2013) -
@DavidPS good point, I may resume a daily dose of magnesium bisglycinate I have lying around in my cupboard, it seems that both glycine and magnesium are nutrients we can't get enough of.
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@Sitaruim said in Chris Masterjohn: Salicylates are Toxic:
I'm not a regular aspirin user but I take it roughly twice a month when I'm feeling sluggish and usually feel a substantial energy boost from it.
As long you're aware of possible side-effects and your counteract them, it's well pro-metabolic.
As long you metabolize well (kidneys and liver), if you don’t overburden …
The liver metabolizes salicylic acid into its active forms and then conjugates it with glycine, forming salicyluric acid. Subsequently, the kidneys excrete salicyluric acid and other metabolites, effectively neutralizing and eliminating the salicylic acid from the body.I've this doc in my PC wallet on the Possible side effects:
Pregnancy and Breastfeeding
Salicylates are not recommended during pregnancy, so pregnant and breastfeeding women should not take willow bark.
Interactions and Depletions
Because willow bark contains salicylates, it might interact with a number of drugs and herbs. Talk to your doctor before taking willow bark if you take any other medications, herbs, or supplements.
Willow bark may interact with any of the following:
Anticoagulants (blood-thinning medications): Willow bark may strengthen the effects of drugs and herbs with blood-thinning properties, and increase the risk of bleeding.
Aspirin acts on blood platelets by inhibiting cyclooxygenase, an enzyme that plays an important role in platelet aggregation, permanently, i.e., for the entire lifespan of the platelet (between 7 and 15 days). In this way, it facilitates circulation and can be used to prevent heart attacks by preventing the formation of clots (thrombosis).
Beta blockers: including Atenolol (Tenormin), Metoprolol (Lopressor, Toprol-XL), Propranolol (Inderal, Inderal LA). Willow bark may make these drugs less effective.
Diuretics (water pills): Willow bark may make these drugs less effective.
Nonsteroidal anti-inflammatory drugs: including ibuprofen (Advil, Motrin) and naproxen (Aleve). Taking willow bark with these drugs may increase risk of stomach bleeding.
Methotrexate and phenytoin (Dilantin): Willow bark may increase levels of these drugs in the body, resulting in toxic levels.Sources:
*) Willow bark sides effects
https://umm.edu/health/medical/altmed/herb/willow-bark
*) Possible Interactions
http://naturaldatabase.therapeuticresearch.com/nd/PrintVersion.aspx?id=955&AspxAutoDetectCookieSupport=1
Comment (LucH): A low posology won’t have the same effect as a high one when taking on several days.