Cyproheptadine (Periactin) - only sedated/relaxed/sleepier so far, are future benefits expected?
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I finally got my 6 packages of 30 tablets 4mg Cyproheptadine (Periactin) from Spain (farmaciasdirect.eu) to cure my post-olanzapine anhedonia, genital numbness (no pleasure in genitals by stimulation even tho normal touch sensation is intact) and no effect by coffee/alcohol/etc. that have PERSISTED now almost a year after QUITTING olanzapine
Few days ago I 1st took 1mg, didn't feel much, took 4mg and had strong sedation/relaxation/sleepiness
From now on I take 1mg daily only
But I haven't felt any other benefits associated with lower serotonin like less anhedonia/more vivid senses/pleasure responses or such
Those who have taken Cyproheptadine, particularly this Periactin produced in Italy
Did new benefits appear after weeks/months of usage?
How long it can take for post-psych med symptom healing to happen by Cyproheptadine and other benefits besides sedation/relaxation/sleepiness to occur?
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@Maximalus I get euphoria from 2mg cyproheptadine mixed with coffee on relatively not full stomach, complete with waking dreams like in an opiate coma. it's as good or better than kratom
anyways 4-6 weeks of cypro is what I would do.
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@sunsunsun You mix it into coffee?
Tablets or liquid Cyproheptadine? Which brand?
How fast the effect kicks in after drinking it?
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Never take Cypro in the evening. It reduces Cortisol. The body needs Cortisol to wake up, being unable to do that is where the grogginess comes from. Cypro isn't sedative by itself, it just removes the barriers (stress hormones) that prevent you from sleeping.
That means you need to take it at least 16 hours (better more) before your wake up time, so most of it is cleared by the time you need to wake up and you can have your daily cortisol spike.
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What it means if I don't feel the anti-serotonin/pro-dopamine effects like less anhedonia/increased sense vividness, high pleasure response and such?
I'm taking it to cure my post-olanzapine symptoms that are basically the same as PSSD many get by SSRIs, but in my case by an antipsychotic - anhedonia (less vivid senses/pleasure response), genital numbness (no pleasure in genitals during stimulation, but normal touch sensation intact) and no effect by coffee/alcohol/etc. are the main ones
Can I expect new benefits to appear after long-term Cyproheptadine use that I don't have currently?
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@sunsunsun Can I dissolve Cyproheptadine (Periactin) tablet in coffee and it'll still absorb/activate?
ChatGPT says it's designed to be absorbed in gut and swallowing or dissolving it in a drink may not let it absorb properly