Fenclonine

alfredoolivas

Estradiol valerate, pramixepole, modafinil and trenbolone acetate to reduce le stress hormones

engineer

Estradiol valerate

alfredoolivas

@engineer since you are their number one customer please kindly ask PPL to send me a bottle. Threaten them with purchasing T Iso elsewhere if need to.

engineer

@alfredoolivas ok, but what are you going to use the estradiol valerate for? that has to be the most unpeaty thing I know of unless you crashed your e2 with too much exemestane.

alfredoolivas

@engineer Intuition.

hwisdom

@engineer fentclonine is a scam, overhyped drug spread by that famous twitter post because of the chicks participating that tried to rape the scientists

fenclonine's real name is para chloro phenylalanine, its a chlorinated version of the amino acid phenylalanine where it has one singular chlorine atom at the para position of the phenyl ring, basically a chlorinated version of the amino acid

if you know what phenylalanine is, you would see that on top of it beeing a substrate for tryptophan hydroxylase, its also a substrate for tyrosine hydroxylase, the rate limiting enzyme for dopamine production, hence why this same study showed that fenclonine negated the effects of the anti depressants they were taking (that worked dopaminergically

hwisdom

@engineer said in Fenclonine:

Neither did the hats. She just felt like wearing them—or, really, any item that would cover her head. A gray wig. A red fedora.

nigga destroyed her crown chakra

hwisdom

@engineer said in Fenclonine:

This one could work, but where perhaps can I procure such a substance?

ngl just look up "buy selegiline perscription free [your country]"

I ended up buying it from bgpharmaceuticals.to
they need you to buy stuff for at least 90 ish dollars, I ended up buying 3 packets of turkish thyroid (100x 50mcg t4 12.5mcg t3) and 1 packet of t3 (100x 25mcg t3) , doxycycline and selegiline, quite cheap if u woulda asked me

edit: forgot to say, but this nigga takes like 4 weeks to ship your shit, and doesnt respond to emails

hwisdom

@alfredoolivas whats w modafinil beeing good for u, its mechanism is it beeing pro histamine

alfredoolivas

@hwisdom If i was doing stuff that was good for me, i wouldnt have an account.

hwisdom

@alfredoolivas hahahahahahaha oh wow

engineer

Last one

https://kevinmd.com/2025/11/a-cautionary-tale-about-pramipexole.html

I never thought I’d be the cautionary tale.

For decades, I worked at a financial company. I’m a youth sports coach, a husband, and a father of two. I’ve spent decades coaching, mentoring players, and proudly producing high school sports telecasts. I built a life around leadership, precision, and community.

But none of that prepared me for what happened when I was prescribed pramipexole (Mirapex) to treat Parkinson’s.

The warnings were there: compulsive behaviors, gambling, and hypersexuality. I read them. I nodded. I thought, That won’t be me.

But pramipexole doesn’t come for you like a thunderstorm. It rewires you slowly. Quietly. It doesn’t feel like addiction. It feels like urgency. Like logic. Like a voice that sounds like your own, telling you this next step makes sense. Until it doesn’t.

I lost control. I made choices that devastated my family. Financial ruin. Emotional collapse. The kind of betrayal that no apology can fix. And when I finally came out of the fog (when I tapered off the drug and the compulsive pull vanished), I was left with the wreckage. The clarity came too late.

Since tapering off pramipexole, the compulsive urge is gone. It’s not dulled. It’s not managed. It’s gone. I don’t feel the same pull, the same irrational need, the same hijacking of my thoughts. That switch, the one that used to flip without warning, is silent now.

But that doesn’t undo what happened.

I sit here now knowing that I have ruined the life of my family. I realize there is nothing I can do to change what my brain did under the influence of that drug. I gambled away everything that would have made a life for my children and my wife. What I’ve done is costing me more than I ever imagined: not just the money I lost, but the tax consequences that may prevent my children from finishing college, and burden my wife for the rest of her life.

And I still have Parkinson’s. That won’t get better. I will need help, help I won’t be able to give myself. And my wife won’t be able to be everything for me or for herself. I fear what that means for her. For us.

I feel useless. Guilty. Ashamed. Like I’ve taken a step backward. But I also know this: I’m not hiding anymore. I’m telling the truth. I’m seeking help. I’m writing every day. And even if I can’t fix what’s broken, I can make sure no one else walks into this blind.

Here’s what I need you to understand: The risks and warnings won’t protect you.

You can read them. You can believe you’re immune. But pramipexole doesn’t ask for permission. It changes how your brain processes risk, reward, and impulse. And by the time you realize something’s wrong, you may already be deep in it.

This isn’t just a medical side effect. It’s a neurological hijacking. And it nearly cost me everything.

If you or someone you love is taking pramipexole (or any dopamine agonist), please don’t dismiss the risks. Monitor behavior. Ask hard questions. Don’t wait for the damage to show up before you act.

I’m not asking for forgiveness. I’m asking for awareness, for accountability, and for a system that doesn’t bury these risks in fine print. And for families to know that if something feels off, it might be more than just stress. It might be the drug.

This is my story. And I’m still living it.

RAY. PEAT. Wonder if he was laden with estrogen and PUFAs!

engineer

The connection between dopamine and serotonin

https://haidut.me/?p=2830

It just so happens that dopamine and serotonin have an inverse relationship. Each one suppressed the levels of the other. Thus, when serotonin is high dopamine is low and vice versa. That relationship extends to synthetic molecules that mimic the effects of serotonin or dopamine at the receptor level. For example serotonin agonists suppress dopamine synthesis and vice versa.

Serotonin (5-HT) promotes blood vessel thickening, may cause cardiovascular disease (CVD)

Serotonin (5-HT) may drive brain/liver/pancreatic and many other cancers, at the genomic level

Serotonin (5-HT) increases inflammatory mediators (IL-6, NF-kB), may cause atherosclerosis

SSRI drugs, serotonin (5-HT) can cause chronic fatigue syndrome (CFS)

Blocking serotonin may treat obsessive-compulsive disorder (OCD)

Drop in dopamine behind giving up

And it goes on and on and on!

https://haidut.me/?s=serotonin

Looks like maybe microdosing a DA could be the way to go?

Edit: Looks like the weird side effects from DAs are truly just a stress response?

https://lowtoxinforum.com/threads/dopaminergic-drugs-like-bromocriptine-may-treat-alcoholilsm.11828/