Glucose loading cures everything?
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@Razvan Another possibility is a herxheimer reaction due to the brain healing. One of the first things that happpened to me on dextrose was swelling, and I'm still experiencing that in various parts of my body to a lesser degree. I've never experienced brain healing before so have no point of reference, but I do become sleepy after 3 or so doses of dextrose.
Dr. Stephens told me (email) you will experience a few "bumps" on the protocol. I'm waiting to hear back to schedule a consultation with him. Maybe I'll have a clearer picture of what's happening.
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@evan-hinkle said in Glucose loading cures everything?:
so maybe a quarter tsp or so of added salt per meal
Thanks Evan. I'm not reducing what's going on here to this, but still...
That doesn't sound like very much to me and Jennifer is certainly right about this.
I agree that salted food tastes over-salted after a period of reduced salt intake.
In my experience if I'm lacking in it for a while, I have to slowly ramp up. Or resist a thirst response. And vice versa. If I overdo it. I have to slowly add water. And resist a salt taste. But the latter is very rare for me these days.
I consider Rays "salt to taste" line a cautionary. Because so many people in so many different states would pick up on it. Haidut and others posts on RPF were more useful to me in pushing the boat, so to speak. And finding out that more was better, for me.
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@Insomniac I agree. I'm also following the protocol, but started taking a regular dose every 2 hours, and stopping when I get sleepy. Large random doses may be causing some of the "scary" symptoms a few are reporting.
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@Insomniac 25 grams 4 times a day is the beginning protocol.
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@Insomniac I've also read everything and listened to every podcast I could find. There IS science to back this up so definitely not "faith based."
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@S-Holmes
I've read his book and have been curious about this protocol for a while. But I don't want to gain weight. I already gained using progest-e that seem to not work for me at all. (female 59)
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@happyhanneke I don't seem to be. Aside from the initial water retention I seem to be holding.
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@Insomniac I get it. Being cautious is never a bad idea. There are enough of us willing lab rats that it's ok to sit this one out.
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@Insomniac I wonder what the rest of their diet looked like. You can't eat fast food and fries every day (I never do). His 100% cure rate is from people who actually worked with him. It isn't fair to judge him based on anything other than that.
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Hello there.
I've started this a week ago and I'm on 200gr of dextrose per day.
The first night was filled with vivid dreaming of a kind I probably have had to catch up with for a very long time (I dreamt of a prior surgery experience when I had actually been under full anesthesia). However, the 25gr's effects waned after about 3,5-4 hours. Whenever this happened, my pulse rose for no reason (I've been having this for years).
About half an hours after the next dose, the dextrose's effect kicked back in for me and I was calm and off to another 4hrs of deep yet eventful sleeping.About two days in I suddenly had watery diarrhea for half a day.
About a day or two later, I had strong gastrointestinal cramping with a high frequency of almost spastic bowel movements. These were relieved several hours after ingesting psyllium and activated charcoal. I suggest glucose definitely sets some things in motion about restoring forwards peristalsis/motility of the gut and digestive organs.The pure dextrose is really totally different to sucrose or honey. Pure dextrose powder is also so much better than those sour little fruit-flavoured dextrose tabs/lozenges available for purchase. Those are sickening after only a few and had been my only prior experiences with dextrose.
After a couple of days, however, my high pulse remained and it felt as if the dextrose had no more effect. I was also craving something which at first I mistook for being thirsty or hungry:
I need a few mgs of thiamin with each dextrose dose and 1.5grs of potassium chloride. The latter tastes surprisingly extraordinarily good with dextrose.
Both potassium and chloride ions are essential for increasing glucose phosporylation, intracellular (structured) water and volume, and the full-on insulin production and release from pancreatic beta cells. Fructose inhibits all of that.
Sodium is shit. Sodium enhances the cortisol and adrenaline signalling and by this is contrary to the utilization of glucose.
With these, thiamin and potassium chloride, the dextrose dosing has been working for me for the past days without weird cravings and its effects also seem to not wane as quickly as before (heart rate, etc). So I will continue with this regimen and perhaps increase it every week.When I tried 50grs dextrose in the beginning, that was too much as my stomach felt heavy and I had a mild feeling of nausea.
Please give it some thoughts and a try yourselves. I would like to hear others experiences also for the chloride supply without sodium.
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@CrumblingCookie said in Glucose loading cures everything?:
Sodium is shit. Sodium enhances the cortisol and adrenaline signalling and by this is contrary to the utilization of glucose.
Not according to renal function, Ray Peat, and my experience it isn't.
But hopefully we can shed some light on what's separating us.
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@ThinPicking said in Glucose loading cures everything?:
Not according to renal function, Ray Peat, and my experience it isn't.
But hopefully we can shed some light on what's separating us.
I would be very interested in seeing this salt mysterium lifted. I hypothesize that a lot of the benefits felt from sodium chloride are due to the chloride ions. And in spite of the actual sodium fraction unless there's some acute benefit from its upping of adrenal hormone functions.
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@CrumblingCookie said in Glucose loading cures everything?:
I would be very interested in seeing this salt mysterium lifted.
I think this has been done in the last 15 years at least. And RPF is a goldmine if you don't have an existing archive.
However my comment above was more for the room because your rejection was strong. If you're struggling with sodium, assuming you've had that trouble with it added to solid food, not in attempt to find a concentration above hypotonic in a drink that "works" for you, and assuming you hadn't been adding a bolus of fluid on top of that food. Please don't change your behaviour or doubt yourself for the comment.
I'm currently down a few rabbit holes about this paradigm split. Which has been present for a lot longer than 6 months, I just didn't notice. Generally I'm paying far more attention to things I have no need to see for the whole experience. And hopefully for your benefit more than my nerd. There's obviously a reason nature likes fructose after all.
CC. Are you also a vitamin A disrespector?
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@CrumblingCookie
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@CrumblingCookie So you just created the account to say a bunch of trash? Hmmm.. suspicious.
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Raz... I know. I know.
But something is going on with them. Do you have people in your life who never seem to eat fruit or put sugar in tea or coffee? Because I do. Beside a monologue about oxidative metabolism, I never thought twice about it. Until recently. Maybe this is less of a thing in Romania (sorry if I got the place wrong).
Holmes was already here. And she started the thread. Only Brad can stop this being a thing really.