Glucose loading cures everything?
-
On a potential side quest with chlorine dioxide, sodium chlorite, hydrogen peroxide:
In the results of his 1986 review on "The Therapeutic Use of Intravenous Hydrogen Peroxide", a therapeutic concept which is said to be equal in effect to the use of hyperbaric oxygen chambers, Dr Charles Farr described an "all-or-none" switching to a metabolic rate at about twice the baseline level brought about by the increased oxygenation. I found this interesting, because an increase of the metabolic rate, although reliably sustained over the long-term, is, after all, what I'm after with the glucose protocol.
He wrote that this was independent of using a 5% dextrose solution along with it or not.I believe the latter finding does not hold true over the medium or long term and certainly not for everyone. That doubling of the metabolic rate must be fed somehow.
Surely, a shift from anaerobic to more aerobic metabolism bears a huge energy potential in the amount of ATP produced from the same amount of substrate and this could be all it takes for some. But what when tissue and liver glycogen already are or become depleted?
I don't know about the raise in efficiency or level of beta-oxidation of fatty acids from oxidative therapy. I certainly know, however, that excessive or extended oxidative therapies become very exhaustive and are not crucially alleviated by the proposed repleting of antioxidants.
Hence, I am now thinking that a huge stumbling block in any oxidative therapy will be stress and catabolism by lack of energy.Cue in the dextrose!
Given that OXPHOS needs glucose and oxygen as substrates, increasing both ought to complement each other reciprocally. More oxygenation may enhance the efficiency already of small serving sizes of dextrose. Or perhaps more oxygenation may ultimately also increase/accelerate the utilisation of greater amounts of dextrose.Do you people think this to be a meaningless oversimplification?
Or is such oversimplification right spot-on since we are already engaging in the almost ludicrously simple needs for glucose and its significant results?To me, the fact that @GlucoseOrBust was recommended by DS to try methylene blue twice a day (in absurdely high amounts, imo) seems to tap right into this context of providing more oxygenation deep down into the tissues along with providing the glucose.
However, I deem methylene blue to be a derivation too cumbersome and too alienated of the in overall more fundamental sources for circulatory and tissue oxygen.
Unless DS purposefully intended to put him into MAO-blocking for the misled goal of raising adrenaline, noradrenaline, serotonin. Which can be greatly helpful for some, but shifts to adrenergic hormone signalling and is kind of a shot in the foot, leg, guts and brain, metabolically.
@GlucoseOrBust Did he explain to you why MB other than by "He heard from someone he has trained that their clients were seeing benefits with combining MB with dextrose. It seems to show some glucose uptake benefits in some studies"? -
@CrumblingCookie Have you come across any information about ozone IV's being helpful? I've been thinking about giving that a try as adjunct to the glucose.
-
For what it's worth, Stephens talks about glucose, oxygen, and water being the three critical factors of energy metabolism. I know it's not groundbreaking science, but maybe a good reminder as to how healing could be more simple if we look at the macro picture first. Anyway, he says that oxygen and water optimization are easier to diagnose as we get clearer signals from the body that we are deficient (air hunger and thirst to put it simply). I think this is an oversimplification, as studying things like Buyteyko breathing shows that air hunger is a subjective experience based on an individuals tolerance to CO2 build up in the lungs and blood. Buteyko helps to reset this air hunger set point to allow greater CO2 in the blood, which paradoxically allows MORE oxygen to be taken up by the cells. Also, it seems that chronic dehydration without a persistent thirst signal is also quite common, at least with regards to lab biomarkers indicating such.
Dr. Stephens is clearly onto something with dextrose in large-ish doses with regards to healing. I think he has seen countless miracles with it, but has put together a kind of patchwork theory on how it works after the fact. I think the danger in this is that there are still people with whom large doses of dextrose are not helping after many weeks, and the answer to why it isn't working probably isn't as simple as more dextrose or time is needed. For me, I've gone as high as 24 Tbsp in one dose and I've been on the protocol now for 7 weeks. I think I have explored a reasonable range regarding both dosage and time needed to at least see marginal benefits. I think it would be a safer for him to assume that there is a minority of people that will either respond slowly (or possibly not at all) to pure dextrose loading. Keeping it simple is good and I think the right path. Perhaps this is a bit too simple, however.
I think it's once people have explored high dosing and have given it a month or more that Stephens has lost most of his patients (the 15-20% or so he's mentioned that don't end up sticking to the program. Some people give up, because they are in a cycle of trying one thing after the other out of desperation. I've definitely been there, but not with this one I don't think. I think there has to be another factor that could be limiting this glucose uptake or glucose metabolism in the brain, especially for the most severe cases. Proper oxygenation seems like as good of a candidate as any. I like the idea of experimenting with ozone. I have done ozone suppositories in the past with little benefit, but I wonder if combining them with dextrose could be beneficial? This combined with low dose MB (I've taken the dosage down to 3mg x2 per day) could be helpful. Any thoughts?
-
@GlucoseOrBust Were the ozone suppositories produced at home or under a doctor's supervision?
-
-
@S-Holmes I've had one or two ozone IVs. I can't remember the ozone rate/device setting and session length, nor the details of how exactly I reacted but only that its effects for me were rather contrary to what the GP and nurse expected and that they were a little irritated and closedmouthed about it.
The ozone IV made me quite stressed and exhausted, physically. I had it stopped five minutes early and struggled to walk up a staircase afterwards and must have looked accordingly because a stranger stopped to ask if I'm alright and insisted to help me and eventually stood next to me awkwardly long until she was somewhat sure I won't be tumbling down.I've done a few chlorine dioxide IVs at 120ppm in Ringer lactate solution. I think that's the maximal practical concentration. I also know that lactate's not ideal and anti-metabolic, but it retains ClO2 in solution. That felt really good and warming and clearing my head like a fresh breeze should do.
That was at least a year before my ozone IV experience, though. So I might have been not yet as deep in a hole when I tried the ClO2 IV as when I tried the ozone IV. But the oxidative potentials also differ with +2.03V for O3 and a much milder +1.57V for ClO2 [H2O2 is +1.76V, O2 (and therefore H2O2 after catalase enzyme interaction) is +1.2-1.4V].
IIRC I had tried 240ppm but stopped it already after a few minutes because of venous irritation.
I had also tried subcutaneous infusion, known as hypodermoclysis. That didn't pan out for me at all as it simply didn't disperse but caused a swelling of half a tennis ball until I stopped. I suspect the max. ppm for hypodermoclysis is even lower. Also, I'm no professional with only little experience on myself (one-handed, of course, in the case of IVs).
Dr. Harmut Fischer (Chemist in Germany) spoke of 120ppm ClO2 in Ringer's.
Dr. Noel Rodriguez (GP, theologist in Guatemala) spoke of 30ppm ClO2 IVs at 40 drops/min and even at that low end issued a warning to diabetics about ClO2 IV lowering BG by a lot and that the insuline dosing may need to be set to half or even only a third of the usual. That's quite a clue for the glucose context. -
@CrumblingCookie OMG. Have you tried H202?
-
@GlucoseOrBust I'm wondering if you got more purified hemp oil than ozone. My understanding is that it doesn't remain in solution long, but once it's infused, the "carrier" will be very pure. Does this seem probable or am I mistaken?
-
@S-Holmes Some rave about drinking hydrogen water. My experience with it about 10 years ago was terrible. I may give it another go with the glucose therapy and see what happens.
-
@S-Holmes The smell of ozone coming off of these suppositories is overwhelming. Not to be gross, but the little bit that you get on your fingers stays there for hours. The ozone is extremely strong. Also, (incoming grossness again), your BMs after using the ozone smell like ozone and have no typical BM foul smell to them whatsoever. The ozone concentration is plenty high, at least with regards to the highly unscientific smell test..... sorry
-
@GlucoseOrBust Interesting.
-
@GlucoseOrBust One more question. I learned from a doctor who does alternative therapies (friend of my RN daughter) that therapeutic ozone MUST be mixed with oxygen. Many ozonators operate without an oxygen tank, like the one I use for room purification (I leave the room, close the door, and then air the room out afterward.) He said that when ozone mixes with nitrogen in the air, it becomes toxic. This is probably a stupid question, but do you know HOW the oil was infused? Did they use oxygen?
-
@GlucoseOrBust said:
For what it's worth, Stephens talks about glucose, oxygen, and water being the three critical factors of energy metabolism.
I think this is an oversimplification, as studying things like Buyteyko breathing shows that air hunger is a subjective experience based on an individuals tolerance to CO2 build up in the lungs and blood.
! Thanks. Wow. It fits together. Now I feel the need to read up on Buyteyko breathing.
I've heard military special forces apply very specific breathing techniques in high-stress situations which probably limit the glucose-inhibiting aftermaths. Is that the Buteyko?
It's very important that you mention the 15-20% of people who dropped out of the glucose protocol even with DS. They could very well all be nonresponders because of missing links.@S-Holmes said:
OMG. Have you tried H202?
I am looking into that now and am open to try it orally.
Maybe as small volume H202 enemas every other day, too, instead of GlucoseOrBust's suppositories. I either need the H202 solution free of stabilisers or find out whether I can neutralise the common phosphoric acid stabilisers with calciumcarbonate.
The recommendations are to use distilled water and definitely no minerals, proteins or vitamins with H202 as they can become much stronger oxidants than the H202 itself. Glucose, however, appears to be fine to be concurrently combined with H202?
As far as I understand so far, the catalase in the stomach lining needs to gradually increase its activity and will convert pretty much all of H2O2 to oxygen? But even in IVs, the H202 is said to be converted to oxygen within a fraction to a couple of seconds. -
@CrumblingCookie said in Glucose loading cures everything?:
@GlucoseOrBust said:
For what it's worth, Stephens talks about glucose, oxygen, and water being the three critical factors of energy metabolism.
I think this is an oversimplification, as studying things like Buyteyko breathing shows that air hunger is a subjective experience based on an individuals tolerance to CO2 build up in the lungs and blood.
! Thanks. Wow. It fits together. Now I feel the need to read up on Buyteyko breathing.
I've heard military special forces apply very specific breathing techniques in high-stress situations which probably limit the glucose-inhibiting aftermaths. Is that the Buteyko?Buteyko is about reducing the volume of each breath in and out your nose. Over time, this resets you CO2 tolerance (level at which you experience air hunger) and allows you to breathe less air breathing less air allows more carbon dioxide to remain in the blood, which transports more oxygen from the blood into cells.
-
@S-Holmes I'm not sure about this. I haven't heard that it matters. Ozone is O3 (three oxygen atoms), so technically made "with oxygen."
-
@CrumblingCookie I tried food grade H202 in water a few times, and again recently. I can't do more than 3 drops without feeling sick.
I like the idea of increasing C02 and I make fizzy water for my glucose syrup. But I wonder if acetazolamide would work even better. I remember that there's a B vitamin similar to acetazolamide. Will need to look it up.
-
@S-Holmes said:
I tried food grade H202 in water a few times, and again recently. I can't do more than 3 drops without feeling sick.
Which percentage of H202 did you use 3 drops of and was it pure or with stabilizers?
Some nausea is always to be expected from oxidative therapies, unfortunately. The use of GI binders can help it go away until the dose can be increased.
But what if glucose will substantially help with such nausea, as it nourishes the essential liver functions AND prevents the BG from dropping which causes nausea?I'm becoming really excited about what you guys can figure out and how this can also help me.
And perhaps even accelerate and complete the results for the 80% and enable the 20%. All of whom are good people, I hope. I only want the intrinsically good people to be finally helped. Not the nasty ones in their capacities. As the nasty ones demand stupendous gains even among themselves, I like to imagine that the odds are in my favor and word of mouth could spread like wildfire among the remains of humanity. -
@CrumblingCookie I concur. I love RP people, and especially the ones posting in this thread (since the antagonists left and started their own).
-
@CrumblingCookie Purechem 35% food grade, zero stabilizers.
-
Can someone please fill me in on the thought process behind oral H2O2 therapy and a good resource(s) to learn more about it? I assume one of the benefits is to improve overall tissue oxygen levels within the body?