Microplastics – known endocrine disruptors- found in blood, gonadal organs
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The findings of this study are particularly alarming as they suggest there are now endocrine disruptors, likely present in the majority of people, capable of causing structural changes and physical damage long before the long-term endocrine effects get a chance to accumulate and cause harm on their own. Namely, the study below found microplastics in four (4) out of five (5) male patients diagnosed with erectile dysfunction (ED). Now, as is probably obvious to all readers, these microplastics did not get lodged into the male reproductive organs directly. They got transported there by the vascular system and their origin is likely the various foods and drink we consume that were packaged in plastic containers/bags. As such, all other highly vascular organs (and especially the heart, as a study author noted) are likely to have similar accumulations of microplastics. As suggested above, putting their endocrine disrupting effects aside, those microplastics directly cause endothelial damage by physically injuring the blood vessel walls, which results in a chronic low-grade inflammation response in said vessels. That low-grade vascular inflammation is a known cause of cardiovascular disease (CVD), dementia, mental conditions, and even cancer. In some cases, if the microplastic particles are big enough, they can cause blockage of a specific vessel and lead to an ischemic event, which in the case of an organ such as the heart (e.g. heart attack) or brain (e.g. stroke), can be lethal. Unfortunately, since there is no known way to trigger the removal of those plastic particles, the only “solution” (as the study authors themselves state) is to avoid using plastics as much as possible in our daily lives. Given just this issue alone, it is little wonder there is an infertility epidemic in most “developed” countries, where the usage of plastics is ubiquitous. Those microplastics in our bodies are both chemical (through their endocrine effects) and physical (through the physical damage/blockage they cause) contraceptives, in both men and women.
https://www.nature.com/articles/s41443-024-00930-6
“…Male infertility remains a global issue, with its causes often not well understood. Given the growing evidence of microplastics infiltrating various biological systems, such as blood and lungs, researchers are now exploring their potential effects on reproductive systems. Previous research has investigated the presence of microplastics in male reproductive organs. For example, in one study, researchers discovered 12 different types of microplastics in the testicles of dogs and humans. In dogs, they found that higher levels of certain microplastics correlated with lower sperm counts and reduced testis weight. Now, new research published in IJIR: Your Sexual MedicineTrusted Source has revealed that four out of five penis tissue samples from five men contained seven different types of microplastics. These polymer fragments can vary in size from less than 0.2 inches (5 millimeters) to as small as 1 micrometer (1/25,000th of an inch). Smaller fragments, known as nanoplastics, are measured in billionths of a meter. Microplastics form when larger plastic materials degrade chemically or wear down physically into tinier pieces.”
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@haidut thank you
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This report suggests microplastic emissions from wind turbines, and Bisphenol A in particular, could be a significant problem. The report's claims are contested/"fact-checked" by wind-energy-industry-supported researchers, which makes me take it more seriously.
A surprisingly large percentage of the turbine's mass is lost each year from friction, seawater, etc., implying microparticle emission flows of substantial mass.
https://docs.wind-watch.org/Leading-Edge-erosion-and-pollution-from-wind-turbine-blades_5_july_English.pdfThe turbines are a large proportion epoxy, with high Bisphenol A content.
"Remember that Bisphenol A amounts to approx. 13 - 15% of casting weight of a turbine blade." -
IIRC the highest amount of micro plastic is from what we inhale ! That's even harder to avoid.
Plus they combine with heavy metals in the body which makes them even harder to remove .Dare to think.
My X:
x.com/Metabolicmonstr -
Nano plastic and forever chemicals (PFAS) bind to the milk protein and to myoglobin, disrupting their function.
https://www.sciencedaily.com/releases/2024/07/240711132144.htm -
@Mauritio pectin interaction
https://phys.org/news/2022-06-interaction-nanoplastics-pectin-water-soluble-polysaccharide.html
https://www.sciencedirect.com/science/article/abs/pii/S2213343722009277https://www.tandfonline.com/doi/full/10.1080/10643389.2023.2195798#d1e1308
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312509/"world," as a source of new perceptions
more https://substack.com/@cs3001"Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"
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Haidut on rpf: https://raypeatforum.com/community/threads/high-metabolism-quickly-destroys-chelates-endocrine-disruptors-like-bpa.25937/
Now this new study below shows that chemicals like BPA are highly vulnerable to reactive oxygen species (ROS). The authors used a type of "photodynamic therapy" to generate ROS and destroy more than 99% of the BPA in the sample after just 2 hours of exposure. Unfortunately, the mechanism they used would be toxic in people as they used titanium dioxide and UV light as catalysts for ROS generation. Fortunately, there are safer methods that have been shown to work in humans. For example, simply having higher metabolism means generating more ROS. As such, thyroid, progesterone and avoidance of PUFA may be able to achieve the same but likely over longer periods of time. This matches well with Peat's response when asked about endocrine disruptors - i.e. he said simply keeping metabolism high is probably the best protection. However, at some point of tissue saturation with the disruptors, another approach may be needed. Perhaps the safest approach to implement this in humans is with methylene blue (MB) and red light. Either one of these on its own has been shown to increase ROS generation. In the case of MB, this effect starts at tissue concentrations of about 1 uM/L, which for most people can be achieved with doses of 3mg-5mg.
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@cs3000 said in Microplastics – known endocrine disruptors- found in blood, gonadal organs:
@Mauritio pectin interaction
https://phys.org/news/2022-06-interaction-nanoplastics-pectin-water-soluble-polysaccharide.html
https://www.sciencedirect.com/science/article/abs/pii/S2213343722009277https://www.tandfonline.com/doi/full/10.1080/10643389.2023.2195798#d1e1308
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312509/Thanks that's awesome.
Apples for the win (again).
And the amount was pretty small as well at 15mg/L ."...ingested MPs can pass through the gut barrier, be translocated through the systemic circulation, and accumulate in distant tissues including the brain, liver, and kidney."
That's pretty concerning though. And I don't know if pectin would help with micro plastics once it has accumulated, since pectin doesn't absorb and should only take care of the MP that is present in the stomach or gut as long is it's present.Maybe modified citrus pectin (MCP) would be a better option in that case because it actually does absorb.
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Microplastics in the Olfactory Bulb of the Human Brain (2024)
Key Points
Question Can microplastics reach the olfactory bulb in the human brain?Findings This case series analyzed the olfactory bulbs of 15 deceased individuals via micro-Fourier transform infrared spectroscopy and detected the presence of microplastics in the olfactory bulbs of 8 individuals. The predominant shapes were particles and fibers, with polypropylene being the most common polymer.
Meaning The presence of microplastics in the human olfactory bulb suggests the olfactory pathway as a potential entry route for microplastics into the brain, highlighting the need for further research on their neurotoxic effects and implications for human health.
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yo, didnt you post something months or years ago on RPF about retinol destroying or detoxing micro plastics?
