Sup stack ideas for Anxiety, Stress, Depression, OCD

Cearrson

GF struggles alot with the aforementioned things, and has been quite irritable since coming off her SNRI. Currently Daily she does the following:
L-Theanine Powder (100mg) or a cup of Matcha (even the matcha doesnt have as much L-Theanine but I think the caffeine really helps mellow her out as it seems to be more effective than just the powder)
B1,2,3 100mg each
Aspirin 300ish mg daily
D3-K2
Cascara Sagrada pill daily (her acne has flared up I think mostly due to stress, but she started Minocycline just the other day because its relatively harmless and has helped her clear up in the past.)
Occasional supplementation (cycling) with progesterone

Thats about it

I've messed around with Tacovit and cyproheptadine but neither have seemed to have much effect.

I've seen positive things about basically all of the following items in peat quotes/interview or peat adjacent stuff. Any thoughts on any of them?
Magnesium
Agmatine
Lithium Orotate
Pregnenalone
NAC
Glycine
Myo-Inositol
Selenium
clonidine
amantadine
memantine
insoitol
Herbs like Valerian Root, Lemond Balm, Chamomile etc

Just looking for a concise effective sup stack that we can use to help her get her feet under her, I hope this thread can help foster discussion for others with similar issues as well and we can find something that works for everyone, Cheers!

serotoninskeptic

@Cearrson I recommend checking out my thread
https://bioenergetic.forum/topic/3046/5-substances-i-would-take-to-treat-depression-before-ssris-and-why/2?_=1727732324835

Cearrson

@Serotoninskeptic Much appreciated, I will give it a look

splithead_

@Cearrson I've had good results from high dose thiamine, although it doesn't directly affect the symptoms but gives me more energy to meet them. This is a good thread by Jay on twitter. Overall diet changes for easier digestion/sugar/proper fueling is what helped me the most, though I don't have experience with OCD.

Cearrson

@splithead_ Thank you I will take a look

@Cearrson

I think a big factor here is just time, it will take a bit for her chemistry to rebalance.

I’ve had great results with what you’re already doing with the L-Theanine, I dose 225mg twice a day, once in the morning and once in the mid afternoon, effectively keeps cortisol suppressed and has helped immensely with OCD.

If you haven’t already, get her on some gelatin, make sure her calcium to phosphorus ratio is 1:1, plenty of fats and carbs, you know the deal.

Cearrson

@RawGoatMilk88 Bingo, I appreciate this, ill up the L theanine dosages great info thank you.

Cearrson

@RawGoatMilk88 what do you do for gelatin? just straight up incorporating more beef gelatin into the diet?

@Cearrson

Yeah I just make gummies with fruit juice, I use Great Lakes brand, used it for the last couple years without issues.