Bile can serve as a reservoir for funghi, making them harder to treat

[yerrag]

@Mauritio Dandelion root, one of the bitters, helped restore my liver's ability to conjugate or make bile. But I was also taking vco and taurine to help restore that ability.

I noticed my bowels were pale, and during that time, my skin was experiencing allergy. The pale color meant I don't have enough bile production to allow effective secretion of toxins fecally. And my skin became the alternative path for toxin clearance.

[Mauritio]

@yerrag Interestingly I can't find a single study showing cholagogue or choleretic effects of dandelion.

I took dandelion extract for the first time yesterday and it seems to be quite stimulating. Not sure if that was a one time only effect, but I found a study showing that it increases dopamine, noradrenaline and adrenaline.

"T. officinale extract exerts it effects by significantly (p<0.05) decreasing the levels of corticosterone and increasing the concentrations of dopamine, noradrenaline, and adrenaline. "
https://pmc.ncbi.nlm.nih.gov/articles/PMC6340315/

[yerrag]

@Mauritio

I am quoting Deepseek AI on the choleretic effects. I haven't been quite doing personal deep research lately ao here goes:

Yes, dandelion root (Taraxacum officinale) is widely recognized as having choleretic effects.

Here’s a breakdown of what that means in practice:

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How it works

Research, primarily in animal models, indicates that dandelion root extract can stimulate the liver to increase bile production. The effect is attributed to its bitter sesquiterpene lactones (like taraxacin) and other compounds. By increasing bile flow, it may help:

· Improve digestion of fats
· Gently relieve constipation linked to poor bile output
· Support the liver's natural detoxification pathways

The distinction you need to know

· Choleretic: Dandelion root is a choleretic — it increases bile production by the liver.
· Cholagogue: It is often also described as having mild cholagogue action — meaning it may also help stimulate the release of bile from the gallbladder.

Evidence and traditional use

· Traditional herbalism: It’s a classic "bitter" digestive tonic and liver herb, approved by the German Commission E (a respected herbal regulatory body) for dyspeptic complaints and disturbances in bile flow.
· Clinical research: Human clinical trials are limited, but animal studies and pharmacological reviews consistently support its choleretic activity.
· Caveat: Because it stimulates bile flow, it is contraindicated for people with blocked bile ducts, active gallstones causing symptoms, or acute gallbladder inflammation unless under professional supervision.

So, if you were connecting your previous queries — yes, the jump from the slang "cholalogic" to the real medical term "choleretic" leads directly here: dandelion root is one of the classic, evidence-backed examples.

[Mauritio]

@yerrag I am not doubting that it has these effects, I was just surprised that there isnt any studies on it (as opposed to gentian for example)

BTW I took it again today and the stimulating effects seem to be a lot less pronounced already.

[yerrag]

@Mauritio It's admirable that you have caught on to Ray's method of feel when using substances. I slowly become more sensitized such as when I make a connection between feeling skin allergies when I observe a pattern emerge that my skin allergy would coincide with pale stools signifying the lack of bile production. But it's notable that I only make that connection because skin allergy is not a common experience with me that when it happens it stands out for me to be able to make a cause and effect relationship to it. Yet, my pattern recognition ability fails me when I take dandelion root, as I dont feel any palpable effect from taking it. I would only get confirmation that it is working after 2 weeks of taking it when I see my stools look darker followed up by the loss of skin allergy. Still, knowing the skin is a secondary mechanism of detox helps me connect the dots in being able to identify loss of bile production with my liver and gallbladder.

I am not as sensitive as you and Ray when it comes to directly feel the effect of taking aubstances and I have to rely on observing outward effects after a given amount of time to allow for the delay for effects to be observed. I even have to shy away from outright using stacks as opposed to a gradual addition of substances, just to be able to identify which substance has an outsize effect, and which can be removed from the stack because it gives diminishing returns or even has unintended effects that confound rather than elucidate. Still, I rely on feel as much as I can.

Although I am more tech ( personal devices such as bp, spO2, and ECG) and test (blood test as the most common example) oriented, as feel isn't enough for me when I can't rely on it when it is absent.

As to you noting the absence of studies for various herbs in the apothecary of herbal medicine, there are many studies that have yet to be made given the richness that abounds in flora. But for those where studies have been made, many are not searchable despite the efforts of Google to make them aearchable, and many are even intentionally siloed and disappeared. Thus, we are able only to benefit from a small subset of herbs that mankind has discovered if we were to rely on the limited scope modern and commercial medical science and its curators limit us to.