Random, interesting studies
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Lemon balm / Melissa
Anti-estrogenic:
anti-cancer effect against breast cancer . Most effective against estrogen sensitive breast cancer.
https://pubmed.ncbi.nlm.nih.gov/32351599/It decreases the severity of dismenorrhea, again pointing towards an anti-estrogen effect.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6447884/Decreases symptoms of PMS.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4557408/Anti- prolactin/Anti-TSH:
https://pubmed.ncbi.nlm.nih.gov/7202226/
Lowers weight gain on a HFD. Lowers FFAs and triglycerides.
https://sci-hub.ren/10.1016/j.jep.2020.113360
Thyroid:
It seems to be the common opinion that lemon balm is anti-thyroid. The studies that I've read only point towards it being anti-TSH. That's a difference. Peat was against TSH.
"TSH has direct actions on many cell types other than the thyroid, and probably contributes directly to edema, fibrosis, and mastocytosis."
I found a study where they induced hyperthyroidism and indeed lemon balm did lower thyroid hormones - but only in the hyperthyroidism group. Not in the group that only received lemon balm. As you csn see below, in normal animals it had basically no effect on thyroid hormones (MO group).

https://pubmed.ncbi.nlm.nih.gov/2985357/ -
Androgenic and aphrodesiac action of the medicinal plant Lithospermum Arvense (bird millet)
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@Mauritio wow nice! And Lemon Balm is super easy to grow perennial herb. Available in most garden stores. Smells great too!
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@Mauritio do you mess around with any phytol these days? Food or extract… is there a supplement phytol? Or just load up on the skins of nuts and slam seaweeds?

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@dapose said in Random, interesting studies:
And Lemon Balm is super easy to grow perennial herb. Available in most garden stores. Smells great too!
Yes. And I haven't even posted all the cool studies on it . There's more for dopamine, liver health and as an anti-viral.
I've been taking lemon balm extract for over a week. And i finally feel like I'm not about to catch a cold for the first time this winter. It's also very calming and seems to help weight loss. Seems to lower blood sugar noticably. -
@dapose said in Random, interesting studies:
do you mess around with any phytol these days? Food or extract…
Ive ordered a food grade phytol supplement from Spain. Some herb, weed or terpene shops carry it.
I'm looking forward to trying it.Im kinda trying to recreate the 1/2nd generation Gonadin.I already take Diosgenin, now phytol . Next methyl oleate (might be able to accelerate PUFA detox).
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Rose hip
Rose hip increases thermogenesis, browning of white adipose tissue and UCP1 (a lot)

https://pubmed.ncbi.nlm.nih.gov/27980600/Rose hip extract lowers weight gain on a HFD, lowers visceral and liver fat.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3892499/It reduces atherosclerosis,oxidized LDL, total cholesterol and fibrinogen.
https://pubmed.ncbi.nlm.nih.gov/28399420/Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects
https://pmc.ncbi.nlm.nih.gov/articles/PMC4358417/#sec15
https://www.sciencedirect.com/science/article/abs/pii/S0924224416304277 -
@Mauritio
From Wikipedia, the free encyclopedia
Phytoprogestogens, also known as phytoprogestins, are phytochemicals (that is, naturally occurring, plant-derived chemicals) with progestogenic effects.[1][2]Relative to their phytoestrogen counterparts, phytoprogestogens are rare.[1] However, a number have been identified, including kaempferol, diosgenin (found in yam), apigenin (found in chasteberry),[1][3] naringenin, and syringic acid, among others.[2] In addition, 3,8-dihydrodiligustilide from Ligusticum chuanxiong is a potent progestogen (EC50 = 90 nM), whereas riligustilide is a weak progestogen (EC50 ≈ 81 μM).[4][5]
carrot salad by R.Peat delivers apigenin (phytoprogestogen) and absorbs estrogens
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1359176/full
" In mice, NAD+ levels can be elevated via treatment with apigenin, a natural flavonoid that inhibits the NAD+-consuming glycoprotein CD38."
Progesteron synthesis depends on NAD as a cofactor as well as myo-inositol synthase . -
@cedric said in Random, interesting studies:
From Wikipedia, the free encyclopedia
Phytoprogestogens, also known as phytoprogestins, are phytochemicals (that is, naturally occurring, plant-derived chemicals) with progestogenic effects.[1][2]Yes I have posted this very paragraph in this thread before. Not sure how strong Diosgenins progestogenic effects are, it feels more androgenic.
I have posted about syringic acid and the Chinese herb progestogen as well.
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@Mossy I really liked the effects it did worsen sleep though.
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