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    Random, interesting studies

    Scheduled Pinned Locked Moved Literature Review
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    • MauritioM Offline
      Mauritio
      last edited by Mauritio

      Lemon balm / Melissa

      Anti-estrogenic:

      anti-cancer effect against breast cancer . Most effective against estrogen sensitive breast cancer.
      https://pubmed.ncbi.nlm.nih.gov/32351599/

      It decreases the severity of dismenorrhea, again pointing towards an anti-estrogen effect.
      https://pmc.ncbi.nlm.nih.gov/articles/PMC6447884/

      Decreases symptoms of PMS.
      https://pmc.ncbi.nlm.nih.gov/articles/PMC4557408/

      Anti- prolactin/Anti-TSH:
      https://pubmed.ncbi.nlm.nih.gov/7202226/


      Lowers weight gain on a HFD. Lowers FFAs and triglycerides.
      https://sci-hub.ren/10.1016/j.jep.2020.113360


      Thyroid:

      It seems to be the common opinion that lemon balm is anti-thyroid. The studies that I've read only point towards it being anti-TSH. That's a difference. Peat was against TSH.

      "TSH has direct actions on many cell types other than the thyroid, and probably contributes directly to edema, fibrosis, and mastocytosis."

      I found a study where they induced hyperthyroidism and indeed lemon balm did lower thyroid hormones - but only in the hyperthyroidism group. Not in the group that only received lemon balm. As you csn see below, in normal animals it had basically no effect on thyroid hormones (MO group).
      1000026182.jpg
      https://pubmed.ncbi.nlm.nih.gov/2985357/

      Dare to think.

      My X:
      x.com/Metabolicmonstr

      daposeD 1 Reply Last reply Reply Quote 0
      • MauritioM Offline
        Mauritio
        last edited by

        Androgenic and aphrodesiac action of the medicinal plant Lithospermum Arvense (bird millet)

        https://pubmed.ncbi.nlm.nih.gov/2743927/

        Dare to think.

        My X:
        x.com/Metabolicmonstr

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        • daposeD Offline
          dapose @Mauritio
          last edited by

          @Mauritio wow nice! And Lemon Balm is super easy to grow perennial herb. Available in most garden stores. Smells great too!

          MauritioM MossyM 2 Replies Last reply Reply Quote 0
          • daposeD Offline
            dapose @Mauritio
            last edited by

            @Mauritio do you mess around with any phytol these days? Food or extract… is there a supplement phytol? Or just load up on the skins of nuts and slam seaweeds?
            🌰

            MauritioM 1 Reply Last reply Reply Quote 0
            • MauritioM Offline
              Mauritio @dapose
              last edited by

              @dapose said in Random, interesting studies:

              And Lemon Balm is super easy to grow perennial herb. Available in most garden stores. Smells great too!

              Yes. And I haven't even posted all the cool studies on it . There's more for dopamine, liver health and as an anti-viral.
              I've been taking lemon balm extract for over a week. And i finally feel like I'm not about to catch a cold for the first time this winter. It's also very calming and seems to help weight loss. Seems to lower blood sugar noticably.

              Dare to think.

              My X:
              x.com/Metabolicmonstr

              1 Reply Last reply Reply Quote 1
              • MauritioM Offline
                Mauritio @dapose
                last edited by

                @dapose said in Random, interesting studies:

                do you mess around with any phytol these days? Food or extract…

                Ive ordered a food grade phytol supplement from Spain. Some herb, weed or terpene shops carry it.
                I'm looking forward to trying it.

                Im kinda trying to recreate the 1/2nd generation Gonadin.I already take Diosgenin, now phytol . Next methyl oleate (might be able to accelerate PUFA detox).

                Dare to think.

                My X:
                x.com/Metabolicmonstr

                1 Reply Last reply Reply Quote 1
                • MauritioM Offline
                  Mauritio
                  last edited by Mauritio

                  Rose hip

                  Rose hip increases thermogenesis, browning of white adipose tissue and UCP1 (a lot)
                  1000026152.png
                  https://pubmed.ncbi.nlm.nih.gov/27980600/

                  Rose hip extract lowers weight gain on a HFD, lowers visceral and liver fat.
                  https://pmc.ncbi.nlm.nih.gov/articles/PMC3892499/

                  It reduces atherosclerosis,oxidized LDL, total cholesterol and fibrinogen.
                  https://pubmed.ncbi.nlm.nih.gov/28399420/

                  Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects
                  https://pmc.ncbi.nlm.nih.gov/articles/PMC4358417/#sec15

                  1000026189.jpg
                  https://www.sciencedirect.com/science/article/abs/pii/S0924224416304277

                  Dare to think.

                  My X:
                  x.com/Metabolicmonstr

                  1 Reply Last reply Reply Quote 0
                  • C Offline
                    cedric @Mauritio
                    last edited by

                    @Mauritio
                    From Wikipedia, the free encyclopedia
                    Phytoprogestogens, also known as phytoprogestins, are phytochemicals (that is, naturally occurring, plant-derived chemicals) with progestogenic effects.[1][2]

                    Relative to their phytoestrogen counterparts, phytoprogestogens are rare.[1] However, a number have been identified, including kaempferol, diosgenin (found in yam), apigenin (found in chasteberry),[1][3] naringenin, and syringic acid, among others.[2] In addition, 3,8-dihydrodiligustilide from Ligusticum chuanxiong is a potent progestogen (EC50 = 90 nM), whereas riligustilide is a weak progestogen (EC50 ≈ 81 μM).[4][5]

                    carrot salad by R.Peat delivers apigenin (phytoprogestogen) and absorbs estrogens
                    https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1359176/full
                    " In mice, NAD+ levels can be elevated via treatment with apigenin, a natural flavonoid that inhibits the NAD+-consuming glycoprotein CD38."
                    Progesteron synthesis depends on NAD as a cofactor as well as myo-inositol synthase .

                    MauritioM 1 Reply Last reply Reply Quote 0
                    • MauritioM Offline
                      Mauritio @cedric
                      last edited by

                      @cedric said in Random, interesting studies:

                      From Wikipedia, the free encyclopedia
                      Phytoprogestogens, also known as phytoprogestins, are phytochemicals (that is, naturally occurring, plant-derived chemicals) with progestogenic effects.[1][2]

                      Yes I have posted this very paragraph in this thread before. Not sure how strong Diosgenins progestogenic effects are, it feels more androgenic.

                      I have posted about syringic acid and the Chinese herb progestogen as well.

                      Dare to think.

                      My X:
                      x.com/Metabolicmonstr

                      1 Reply Last reply Reply Quote 0
                      • MossyM Offline
                        Mossy @dapose
                        last edited by

                        @dapose Good idea. I'll add this to my planned garden as a medicinal herb. @luch recommends this to calm the gut, and for anti-stress, vagus nerve support.

                        "To desire action is to desire limitation" — G. K. Chesterton
                        "The true step of health and improvement is slow." — Novalis

                        MauritioM 1 Reply Last reply Reply Quote 1
                        • MauritioM Offline
                          Mauritio @Mossy
                          last edited by

                          @Mossy I really liked the effects it did worsen sleep though.

                          Dare to think.

                          My X:
                          x.com/Metabolicmonstr

                          daposeD 1 Reply Last reply Reply Quote 0
                          • daposeD Offline
                            dapose @Mauritio
                            last edited by

                            @Mauritio @mossy i had a cup of lemon balm tea after lunch yesterday and it was very calming, similar to chamomile but not sleepy-calm. My guess is that lemon balm is better for day time stress, and chamomile better for after dinner nighty night time! 🫖 🍵

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