Make Carrier Oils MCT again
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@16charactersitis Show me the peater who is injecting themselves with homebrewed tocopherol + mct based steroid injections. PM is open
In time there is life but no knowledge; outside time there is knowledge but no life
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@16charactersitis you can’t draw tocopherol from a vial and inject it easily as it’s so viscous. If you want to do this, I imagine you will have to inject with a 20-21g needle which is so painful. The post injection pain will be awful.
Thirdly, no one knows the solubility of esterfied steroids in tocopherol.
Fourthly, if you are injecting large amounts of steroids, it’s easy to overdo. For example, a 600mg test cycle will mean you will be injecting around 2 grams of tocopherol a week. Given the oral route has around a 60% bioavailability I think, this means that you will be injecting an oral equivalent dose of like nearly 4 grams of tocopherol a week. This is around 800IU a day. That’s adding a large dose of a supplement to your stack which can change things and be potentially problematic.
For example last summer I was taking 300mg of DHEA and 300mg of progesterone a day in tocopherols, which was dissolved in 3725IU of mixed tocopherols. I was taking in 3725IU of tocopherol a DAY to be able to take large doses of these hormones. Luckily I had no bad reactions but that’s insane dosing that I imagine can be problematic.
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mitolipin is actually a pretty decent carrier for low dose hormones, if the user can handle like 200-400mg of choline a day. that form of choline actually can enhance absorption of substances dissolved in the vitamin E with it as well, I've read.
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@jamezb46 I plan to inject progesterone dissolved in tocopherols this summer. In small doses.
Tocopherol is an amazing solvent for non esterfied steroids. Using benzyl benzoate as a solvent doesn’t work, the solution crashes and you can only dissolve very small amounts of progesterone in it despite it.
Secondly, tocopherol injections have shown to create a depot, that slowly enters the blood stream - in animals, tocopherol injections create a peak in tocopherol blood concentrations 12 hours after injection ! So I can have a slow releasing stream of hormones.
I want to inject progesterone to bypass liver metabolism and to slowly release hormones in my system. Progesterone and other non esterfied steroids have a very short half life
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@eduardo-crispino yes but it’s a shame it costs 40 dollars for 30ml.
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@alfredoolivas There is probably another way to make a chemical like tocopherol that can dissolve alot of unesterified steroids but with a much higher tolerability. If P4 can dissolve at 200mg/mL in tocopherols, and you inject 1mL, that's about a gram of tocopherols, which is alot.
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@jamezb46 yes… the bodybuilding world hasn’t figured this out either as they use propylene glycol, guiacol, ethyl oleate or benzyl benzoate (all of which are inflammatory) and can only create solutions that are 10% testosterone base and cause crippling post infection pain.
I only plan to inject around 8-20mg of progesterone for the reason you mentioned, because I do not want to add in large amounts of tocopherol.
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@alfredoolivas Alright bro here's the plan: I'm gonna synthesize the carrier oil that can dissolve huge amounts of base hormones and create a depot. Then you buy about 100 kilograms of testosterone and 10 kg of DHT and we will dominate the industry by making 1:4 ratio of DHT:T (unesterified) in this mystery solvent (haha, like that will ever happen), but it's nice to imagine,eh
In time there is life but no knowledge; outside time there is knowledge but no life
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@jamezb46 maybe a synthetic variant of tocopherol that is not biologically active could work. Similar to the synthetic tocopherol isomers that are less active
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@alfredoolivas said:
maybe a synthetic variant of tocopherol that is not biologically active could work. Similar to the synthetic tocopherol isomers that are less active
As in simply the S/L (+) enantiomer of alpha-tocopherol perhaps? Nobody should want that anyway you may be able to buy that up as garbage from separatation of synthetic, racemic DL-tocopherol.
Maybe a 2/3 S-, 1/3 R-tocopherol ratio will be already totally useless and balance each other close to neutral.Or an isomer as in pure beta-tocotrienol? R or all-rac.
Probably reducing the length of the phytol side chain severely takes away the solubility along with activity.
On the other hand better just forgo the idea of dissolving pure base and go for cyp or whatever so you should not need 100% vitamin E to gain sufficient solubility. Maybe 30% or 50% in MCT will be right. Maybe add in a max. of 3% DMSO.
@jamezb46 said:
Then you buy about 100 kilograms of testosterone and 10 kg of DHT and we will dominate the industry by making 1:4 ratio of DHT:T (unesterified)
+- 35,000 USD. Go for it!
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@CrumblingCookie Those are interesting ideas for modifying tocopherol, but you'll have to do safety studies before anyone wants to inject it and those cost a lot more than $35,000
