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    Fenclonine

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    • hwisdomH Offline
      hwisdom @hwisdom
      last edited by

      selegiline is btw rlly goated it does live to the hype, better than bromantane imo

      MILF
      man I love fasting

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      • alfredoolivasA Away
        alfredoolivas @engineer
        last edited by

        @engineer inshallah

        engineerE 1 Reply Last reply Reply Quote 0
        • engineerE Offline
          engineer
          last edited by

          If pramipexole doesn't work out, it looks like you can also increase dopamine and (hopefully) lower serotonin through MCR agonism. That would mean a peptide like melanotan 2 or PT-141. I already have some melanotan 2 but the jury is still out on melanoma risk so that means PT-141.

          hwisdomH jamezb46J 2 Replies Last reply Reply Quote 0
          • engineerE Offline
            engineer
            last edited by

            Looks lik maybe MCR agonism is akin to a stress response?

            Appears as though metergoline is the way to go even though it mostly works on serotonin

            Now the challenge is finding bulk metergoline

            hwisdomH 1 Reply Last reply Reply Quote 0
            • hwisdomH Offline
              hwisdom @engineer
              last edited by

              @engineer melanotan makes you black through NO stimulation btw, this is why it also gives u massive boners, prolactinogenic, not peaty, fuck melanotan all these mechanisms abt it are just speculations because "erm akshually melanin good!", didnt peter thiel like fund these popular peptides or smth idfk

              MILF
              man I love fasting

              engineerE 1 Reply Last reply Reply Quote 0
              • hwisdomH Offline
                hwisdom @engineer
                last edited by

                @engineer metergoline is goated, any chinese nigga on echemi would sell it to you for around like 400$ a gram, 4mg a day for me gave me all the famous benefits of blocking serotonin at a significant rate, but if you can try getting ur hands on the brand name Liserdol product, its gonna be much easier

                MILF
                man I love fasting

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                • engineerE Offline
                  engineer @hwisdom
                  last edited by engineer

                  @hwisdom it doesnt specifically touch NO, it just stimulates melanocytes through mc1r which is normally agonized by alpha msh, and NO increases mc1r expression like you would expect in a stress state

                  https://grok.com/share/c2hhcmQtMw_7fd6d676-eb61-41b6-8bff-c75dc29acb22

                  remember, iNOS is bad and eNOS is fine

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                  • engineerE Offline
                    engineer @alfredoolivas
                    last edited by engineer

                    @alfredoolivas said in Fenclonine:

                    @engineer inshallah

                    I just gave mami a Ray Peat starter kit

                    20260424_145843.webp

                    alfredoolivasA hwisdomH 2 Replies Last reply Reply Quote 1
                    • alfredoolivasA Away
                      alfredoolivas @engineer
                      last edited by

                      @engineer you don’t cheap out, I like it

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                      • hwisdomH Offline
                        hwisdom @engineer
                        last edited by

                        @engineer I eat out my dogs asshole

                        MILF
                        man I love fasting

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                        • jamezb46J Offline
                          jamezb46 @engineer
                          last edited by

                          @engineer Maybe you would like Bupropion for this purpose. It's easily available.

                          In time there is life but no knowledge; outside time there is knowledge but no life

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