Fenclonine
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Has anybody tried fenclonine? I'm itching to see what zero serotonin feels like. There appear to be at least these three sources:
https://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=61111 cheapest
https://www.tcichemicals.com/US/en/p/C0253 more expensive but higher purity
https://www.sigmaaldrich.com/US/en/product/sigma/c6506 really expensive
On RPF there is a similar thread but only a couple people took the plunge and felt weird:
https://www.lowtoxinforum.com/threads/affordable-source-of-pcpa-fenclonine.3099/
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@engineer Why not just take a dopamine agonist/reuptake inhibitor
such as:
Cabergoline
Bromocriptine
Pramipexole (more extreme from my understanding)
Selegiline (probably the best option) -
@jamezb46 said in Fenclonine:
Cabergoline
Risk of valvular damage
Bromocriptine
Same
Pramipexole (more extreme from my understanding)
"Newer dopaminergic drugs like pramipexole have not been studied enough, even though they seem OK for now. I agree with Peat's principle to not trust drugs that have not been in the market for at least 20 years. Clinical trials are nothing more than a sharade proving merely that a drug won't kill too many people in too short of a time." - Haidut
Selegiline (probably the best option)
This one could work, but where perhaps can I procure such a substance?
I already have lisuride but it's pretty expensive and only a partial serotonin antagonist. The main reason I wanted to smash serotonin was this:
pCPA was used extensively in the 60s and 70s especially by US military scientist for some unique and I'd say bizarre experiments. It was used as a drug to induce "gay" behavior in humans, but they found out that it simply increased libido dramatically, where in the rats it made them lose preference for sexual partners and made them mount even...cats! So, it's not like the rats became gay, they just lost all fear and dedicated themselves to sexual "exploration" (even with cats), which, as you know from reading Peat, is a hallmark of health.
With such ridonkulicious results, I just have to try a replication study.
Update: Upon doing a little more research, it appears as though fenclonine doesn't work very well in humans, but there isn't much data available.
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https://mexipharm.net/categories/Depression/Emsam
I think phenylpiracetam could also be useful, but if you use it you probably need to look into sleep optimization because some people claim that it induces insomnia.
