Prolactin is an innocent bystander and may even be beneficial
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@cs3000 I agree, the main point of this post was to warn people not to nuke it.
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Human studies
"a 2-3 fold increase of circulating PRL levels maintained for 1.5-3 h exerted no apparent effects on the secretion of endogenous LH, FSH and TSH."
https://pubmed.ncbi.nlm.nih.gov/8258642/"Prolactin does not acutely influence renal electrolyte excretion and probably does not influence water excretion in man."
https://pubmed.ncbi.nlm.nih.gov/870513/ -
Prolactin group had much lower estradiol, but the before measurements were not taken
https://clinicaltrials.gov/study/NCT00438490?tab=results#results-overview
https://pmc.ncbi.nlm.nih.gov/articles/PMC1950489/#sec10
Prolactin group had constantly lower estradiol
Prolactin group ate less
"Short-term prolactin administration causes expressible galactorrhea but does not affect bone turnover:"
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@alfredoolivas so with how good prolactin is, tell us why we shouldn't prolactinmaxx (you know how)
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@engineer I have been doing that with great results.
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thank you all for this incredibly valuable thread. @alfredoolivas thanks for starting it.
I suppose like estrogen, prolactin has its good sides. This has helped me see some more research material I would have missed that I can study.
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After quitting cabergoline, my tiredness has stoppped
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@alfredoolivas at this point I would be worried about not getting in enough food or at least not carb cycling (to lose fat by maximizing carbs only when absolutely needed), because you can feel "not tired" through cortisol which could have been suppressed with cabergoline
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@engineer cabergoline increases noradrenaline though.
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“PRL stimulates steroidogenesis in the testes by inducing or maintaining LH receptors in Leydig cells and/or by affecting androgen biosynthesis in Leydig cells via steroidogenic enzymes activity”
