Posts made by DavidPS

Stephen T. Sinatra (1946 – 2022) was a board-certified cardiologist  specializing in integrative medicine.  He studied coenzyme Q10 in the prevention and treatment of heart disease. His experience with CoQ10 led him to develop a new branch of cardiology: "metabolic cardiology."

Metabolic cardiology involves preventing and treating cardiovascular disease at the cellular level with nutraceuticals  which improve ATP production in heart cells. He wrote, “Bioenergetics is at the Core of Metabolic Cardiology”.

The four nutraceuticals for heart health he referred to as “The Awesome Foursome”:

1. Magnesium:
2. CoQ10: there are two forms one is called ubiquinone and the other is called ubiquinol, ubiquinol is a little more powerful (and expensive), but both work.
3. L-Carnitine: a fatty acid shuttle into mitochondria.
4. D-Ribose: building blocks for your cells energy needs.

Dr. Sinatra wrote that these specific nutrients are worth trying to see if they help you feel better and help your heart and other cells to work well. He made a presentation in 2015 describing the impact of these nutraceuticals on heart health. Here is his presentation which is entitled “Healing the Heart”.

On his website he wrote Metabolic-cardiology-Basics.

Dr. Sinatra also authored several books that are available at retailers.

Lean and healthy old men (~age 70) do not show anabolic resistance to resistance exercise and amino acids.

More evidence that much of aging is actually just letting yourself go and becoming overfat and insulin resistant.

Staying lean and fit fights aging

Anabolic Sensitivity in Healthy, Lean, Older Men Is Associated With Higher Expression of Amino Acid Sensors and mTORC1 Activators Compared to Young (2024)

Postmodern Jukebox ft. Sunny Holiday
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https://www.youtube.com/watch?v=yHqZQve0KWc

Moderna halted a clinical trial of its mRNA vaccine for respiratory syncytial virus (RSV) in small children in September. This week, the FDA disclosed: 12.5% of vaccinated vs 5% in the placebo group developed severe or very severe RSV disease.

Moderna’s mRNA vaccine against RSV takes a tumble

Hyperinsulinemia, driven largely by a junk food diet (and being sedentary), greatly increases the risk of all modern chronic diseases.

It also accelerates aging.

Hyperinsulinemia and Its Pivotal Role in Aging, Obesity, Type 2 Diabetes, Cardiovascular Disease and Cancer (2021)

Dietary polyphenols have beneficial effects on obesity and diabetes by regulating gut hormones such as GLP-1.

Top sources of these polyphenols: coffee, tea, chocolate, and red wine.

Gastrointestinal hormone-mediated beneficial bioactivities of bitter polyphenols (2024)

Hold on to your hats!

Elon Musk Calls For Government Shutdown Over Christmas