@yerrag
That general view of some peaters about lipolysis that you quoted in your reply probably stems from a misinterpretation of what Ray said about it. The emphasis he places on inhibiting lipolysis is in the context of too much PUFA stored in the tissues, which becomes less and less necessary as you become “PUFA depleted”. After that, inhibiting lipolysis becomes more of a therapeutic tool to be used in appropriate contexts, such as in some pathologies.
He even mentions that in healthy people (especially children) stress hormones are only produced in the amount needed because free saturated fatty acids serve as negative feedback, not allowing them to rise beyond what is necessary.
In good health, especially in children, the stress hormones are produced only in the amount needed, because of negative feedback from the free saturated fatty acids, which inhibit the production of adrenalin and adrenal steroids, and eating protein and carbohydrate will quickly end the stress. But when the fat stores contain mainly PUFA, the free fatty acids in the serum will be mostly linoleic acid and arachidonic acid, and smaller amounts of other unsaturated fatty acids. These PUFA stimulate the stress hormones, ACTH, cortisol, adrenaline, glucagon, and prolactin, which increase lipolysis, producing more fatty acids in a vicious circle. In the relative absence of PUFA, the stress reaction is self limiting, but under the influence of PUFA, the stress response becomes self-amplifying.
This misinterpretation is probably one of the bases for the idea that moderately high insulin several times a day is beneficial (because it inhibits lipolysis and increases glucose oxidation). I don't particularly consider insulin to be a “stress hormone”, but high insulin several times a day and for long periods is obviously a bad sign; insulin plays an “enhancing” role and not the main role.
Keto diets, a very low fat and/or very low protein diet, exercise, ACV before meals, walking after meals, and other similar tools aimed at reducing insulin are only necessary if metabolic dysfunction is already present. Is it good to have these options available with the constant attacks on our health? Yes, but the more miraculous a therapeutic tool is, the more likely it is that your health isn't as good as you think.
