@stolkovandrew said in Lower limit MB dose to cause significant pigment alteration in urine:

Semiregular (everyday or every other day) 5mg reliably dyes my urine blue about 3 to 6 hours after dosing. 10 mg usually gets me two or three blue urinations.

Thank you for sharing. The most I’ve taken in a day is 4mg which sometimes give me a green color. I was unsure if doubling that dose would give me my wanted blue urine but it sounds like it should. Will report back soon with pics :).

@Neigher said in Getting rid of gyno:

@peatilian I am interested in solving test and dht into dmso. What is the procedure?

No clue I purchased already solved. Check out alphagels on twitter/reddit if you don’t want to mix yourself.

@donovan said in Lower limit MB dose to cause significant pigment alteration in urine:

@peatilian i have been taking 2.5mg 3-4x week and after a few weeks of doing this I’ve just started to notice blue hue in urine. So on days i lift I’ll cut it down to 500-1000mcg, and on days i train Muay Thai I’ll continue doing the 2.5mg or nothing at all.

Interesting, I notice a slight color change to green when I dose up to 4mg in a day. Maybe if I start 4mg twice a day my pee will turn blue.

@Michigga said in The Bulking Recipe Pt. 1:

You will be immensely hydrated compared to the obese artificially flavored water chuds on social media telling you to "stay hydrated!!!".

Outstanding. The sucralosecels stay losing to the maplesyrup milk chads in the aesthetics race.

@GreekDemiGod said in Getting rid of gyno:

@peatilian Just DHT? Doesn't it crash your T levels and you're obliged to take TRT?

False.

DHT has so little effect on the HPGA (Hypothalamic–pituitary–gonadal axis) that it causes 0 recognizable testosterone production suppresion. Androsterone does not cause any HPGA suppression either.

Have any serotonergic sally's experimented in high dose MB oral use? If so what is the minimum efficacious dose one needs to take to experience blue urinary excretion?

If not too high, I would like to experiment along side anti-serotonergic compounds to turn my urine blue as I think it would be a cool party trick.

@eatfan said in Getting rid of gyno:

@peatilian

Appreciate the reply, did you notice any other effects from the DHT/Andro so far? 16mg seems like a fairly large dose, what made you land at that number? I was considering starting with Andro so would be intrigued to hear any of your thoughts so far, especially that we seem to have fairly similar situations. Thanks in advance.

I have been applying about an hour before the gym, started at 8mg and titrated up to 16 mg quite quickly. Mentally felt very well in the gym and specifically after. Much more dopaminergic after the lift than usual.

It also smells incredible to me so it’s also my daily perfume. No gyno reduction noted so far from the andro.

@anabology

I have linked 2 studies regarding minute doses of glyphosate causing liver/kidney damage with 0 mention of PUFA

https://ehjournal.biomedcentral.com/articles/10.1186/s12940-015-0056-1
https://www.mdpi.com/1099-4300/15/4/1416

@Faceguy said in IPAM (indolepropionamide) extends lifespan of rotifers by 300%:

So it works better on rotifers but would presumably be less effective on mammals? I always knew knew being spineless, cold-blooded, and ciliated would pan out well for me.

The researchers in the linked study added that in the species of rotifier they tested on, IPAM caused the single greatest lifespan increase of any molecule tested in any study.

Obviously the equivalent dosage will likely not cause as potent effects in humans. However, it is an endogenous compound and quite small so it could be taken in larger doses at a small cost. Without as much concern for safety a synthetic drug would cause.

https://en.m.wikipedia.org/wiki/Indolepropionamide

IPAM or indolepropionamide was shown to increase the lifespan of rotifiers by 300%, along with increasing offspring production by 3.4 count, and body size by 1.5 in studies.

A Novel Endogenous Indole Protects Rodent Mitochondria and Extends Rotifer Lifespan

IPAM is structurally similar to melatonin, and found endogenously in mammals. Serves mainly as a mitochondrial anti-oxidant. Shown in studies to increase Complex I and Complex IV in the mitochondrial ETC. Acts as a recyclable electron and proton carrier, enabling a proton gradient that drives mitochondrial ATP synthesis. It acts as a metabolic stabilizer, reducing the amount of reactive oxygen species and protects the mitochondria.

The only large study done on the compound is the 2010 study linked above, tested on rotifiers (very small fish). The 300% lifespan increase is very profound and would be an estimated 150% if tested on mice, although this hasn’t been done yet.

Perhaps @haidut could source and give to some of his lab rats, as this could be a very strong metabolic protecting longevity drug in humans.