Thyroid Log
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So I started using exogenous thyroid again. Some of you may know my history from RPF. Basically, the reason I decided to try thyroid again is the following.
- I continue to struggle with low energy levels, low vitality. My most recent TSH result was 3.4 uUI/ml. It usually hovers between 2.5 and 3.5. When my sleep, rest and nutrition are on point , it drops below 2.
I want to get my TSH dow to 1 or even lower. - Latest blood tests show high LDL, indicating poor conversion into steroid hormones. This is a sign that I could benefit from thyroid.
- I have low Test, hopefully getting the thyroid dose right will raise my vitality, and also my steroid hormones.
- I have low SHBG levels 16nmol/L. I read that thyroid can raise it.
4th April 2024
Starting dose: 25 mcg T4 + 25mcg T3 daily split into 2 doses.
So 2 x 12.5 mcg T4 + 2 x 12.5 mcg T3.Current Temperature:
- morning temp: 36.1 to 36.4 C (96.9 to 97.5 F)
- daytime temp: 36.5 - 36.8 C
Pulse is in the 60s, so quite low.
I'd like to improve TSH, raise temps and pulse in the ideal range. - I continue to struggle with low energy levels, low vitality. My most recent TSH result was 3.4 uUI/ml. It usually hovers between 2.5 and 3.5. When my sleep, rest and nutrition are on point , it drops below 2.
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1st dose (mid-day): 12.5 mcg T4 + 12.5 mcg T3. Increase in temp for 1-2 hours, followed by a crash in the following hours.
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@GreekDemiGod Why take 12.5 mcg in a single dose? I'd advise taking 2-3mcg every 2-4 hours, as your schedule permits, to mimic rhythmicity of endogenous secretion. Exogenous T3 in excess of physiological levels (e.g. the midday dose you took) will be neutralized by the liver and converted into rT3.
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Isn't that too much to take at once? Why not split it up?
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There's a guy who "dissolves" t3 and t4 in water and drinks it during the day. If that's possible, it might be smoother and easier to monitor the effects
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@banquos-ghost AFAIK, only T4 can be converted into rT3.
I'll see how it goes for 2 week.2nd dose (evening-night). Same effect as the 1st dose.
Not sure if I should call it a crash. It just feels like my cortisol is being massively lowered. Perhaps, revealing my true state of metabolism.3rd dose (morning):
wake-up Temp: 36.4 C
wake-up Pulse: 65 bpmWoke up feeling better than usual, my usual morning headache is reduced. Slightly better energy levels.
That low cortisol, no anxiety feeling persists. I'll take it as a good sign.@TexugoDoMel Interesting. Do all thyroid pills dissolve in water?
@Master I want to avoid taking T3 by itself. -
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Day 2
Generally, I've felt better, temps fluctuating between 36.4 - 36.8 C.
Still felt lazy to do my job.
Some palpitation episodes here and there.
Reached 37.0 C (98.6) after my workout at the gym. -
Day 3
wake-up: 36.4 C, 70 BPM.
I've been reading about Iodine deficiency and its role for thyroid health. I realized that I stopped consuming iodized salt about 6 years ago, that's when my health started going downhill.
I will start consuming iodized salt again.
Cronometer says I consume 120 micrograms of Iodine/ day (80% of RDA) -
Iodine is very important but remember that iodine displaces bromide and fluoride and can cause unpleasant symptoms precisely because of this. It's a good idea to adjust the amount of selenium too, as there's a good chance you'll feel unwell when supplementing with iodine if you're deficient in selenium.
You said here:
AFAIK, only T4 Can be converted into rT3.
You're right, but T3 can be converted to diiodothyronine.
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Day 4
Wake-up: 36.5 C, 65 bpm
I’m glad I started using thyroid (again). I really needed it, I was miserable without it. Things are slowly getting better, I feel more alive, more able to engage in my day to day activities.
Temp-wise, I reached 37.0 C at some point, but after that the measurements were more erratic.
I know it takes a couple of weeks for T4 to accumulate and stabilise in the tissue. So we’ll see how it goes.
I will talk to my endo about prescribing me thyroid, but most likely she won’t agree, she will say that my TSH of 3.4 is normal. And if she will agree, she will likely prescribe Levothyroxine only, the standard treatment.
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@GreekDemiGod said in Thyroid Log:
And if she will agree, she will likely prescribe Levothyroxine only, the standard treatment.
Is a T-3 only prescription drug even available in your country? Mine has just T4-only or T3-T4 in standard NDT proportions (and I have yet encounter someone who has actually received the latter), so even if she agrees with you, there might be limited options.
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2 weeks on T4 + T3. Morning temps at a constant 36.4 - 36.5 C, pulse at 70bpm. Daytime temps go up to 37.0 C.
I currently take:12.5 mcg T4 + 6mcg T3 first thing in the morning 2-3 doses of 4-6 mcg T3 spread through the day. 12.5 mcg T4 + 6mcg T3 first thing in the evening/ at night.I definitely feel better and less fatigued that before.
Yesterday, I had the urge to do physical activity, I did a sprinting session.
I believe I could benefit from an increase in dose, but I’m wary of doing it, in the past I’ve experienced high rT3 from increasing T4 too much. -
Things are going well for me. Thyroid is really helping me function better in my everyday life. I'm able to better do my work, I can stay focused for longer, on mental tasks. to pick up chores around the house. I'm slowly breaking out of helplessness.
Yesterday, my morning temp was 36.6 C, pulse 85 bpm. Reached 37.3 C in the evening.
I will stick to my current dose until I reach one month. Then I plan to take blood tests, and increase my T4 dose from 25mcg to 37mcg. -
Spoke 2 soon. Had 2 bad days in a row.
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@GreekDemiGod said in Thyroid Log:
Had 2 bad days in a row.
By bad days you mean worse than before taking thyroid?
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@DonkeyDude yes. Suddenly felt very hypo. Either it’s the liver that I ate having an anti-thyroid effect through Vitamin A, or the T4 I’m taking has accumulated and converting to rt3. I’ve had this happen before.
It’s frustrating cause I’m taking a quite low dose of T4. 25 mcg. How much lower should I go? I should take it more sparingly perhaps. -
@GreekDemiGod What is your vitamin D and calcium consumption like? Eating Vitamin A rich foods without adequate vitamin D can do some weird shit. I noticed this myself. I think it can stimulate PTH whenever there's a D deficiency. I don't know that for sure, but all three A, D, & calcium play integrated roles with one another. For me, when I notice my temps drop, usually it has something to do with PTH.
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3 weeks on thyroid
Switched to 50mcg T4 and 12.5 mcg T3. Currently feeling great. Quality of life substantially improved.
I went to the endo last week, she said that my blood tests are fine and I do t have any problems with my thyroid.
But how can that be possible when I tick all the symptoms of hypothyroidism and see improvements with taking exogenous thyroid hormone? -
@GreekDemiGod If you tick all boxes for hypothyroidism then what symptoms were drastically improved?