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P4 and DHEA in a 8:1 Ratio

The Gym
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  • P
    pannacottas @jamezb46
    last edited by Oct 1, 2024, 7:43 PM

    @jamezb46
    Ok, with injectable P4 and DHEA this makes way more sense. The combination bieng stronger that 350 Test and potentially equivalent to 500+ is insane actually, someone needs to try this and report back! But i wonder if it only works if you have built lots of muscle with androgens first or it can be just as anabolic.

    J 1 Reply Last reply Oct 2, 2024, 2:08 AM Reply Quote 0
    • J
      jamezb46 @pannacottas
      last edited by Oct 2, 2024, 2:08 AM

      @pannacottas

      Well, remember for @haidut anabolic is really anti-catabolic.

      So, P4 he considers to be anabolic because of its anti-cortisol properties.

      I want to belive this, but I find it to be doubtful. If it is really correct that AAS work primiarily through anatagonism of GR, then why don't RU486 or Emodin or beta-lapochone or other cortisol blockers make people jacked? Maybe it is the "synergy" between anagonism of GR and agonism of AR that is the real key.

      That is a line of thinking developed in some of Haidut's other threads on RP forum about, for example, combining progesterone and oxandrololne and the general outline of why the "dutchess coctail" is effective.

      Yes I agree that this needs to be tried and replicated. From about an hour of looking over the Cortinon thread of RP forum, many users reported some issues with comparitvely quite low doses of Cortinon, in the range of 2-4 drops, which is only 6-12mg P4, which pails in comparison to the 120 mg countenanced above.

      In time there is life but no knowledge; outside time there is knowledge but no life

      T 1 Reply Last reply Oct 7, 2024, 6:56 PM Reply Quote 0
      • T
        thyroidchor27 @jamezb46
        last edited by Oct 7, 2024, 6:56 PM

        @jamezb46 oxandralone shuts you down at any dose tho right?

        J 1 Reply Last reply Oct 8, 2024, 12:52 AM Reply Quote 0
        • J
          jamezb46 @thyroidchor27
          last edited by Oct 8, 2024, 12:52 AM

          @thyroidchor27

          Not necessarily. At doses of about 10mg/day there was almost no shutdown.

          Some other steroids such as tbol and dbol also have minimal shutdown at low doses. You could probably get away with running them at around 20 mg/day for 6 weeks and not have any shutdown. 6 weeks on, 2 weeks off. Then repeat.

          That's roughly what the east german athletes did during the state planned doping.

          In time there is life but no knowledge; outside time there is knowledge but no life

          T 1 Reply Last reply Oct 8, 2024, 9:41 AM Reply Quote 0
          • I
            Insomniac
            last edited by Insomniac Oct 10, 2024, 11:00 AM Oct 8, 2024, 1:19 AM

            I never understood why pregnenolone doesn't substitute for progesterone since lots of it converts to progesterone.

            J 1 Reply Last reply Oct 10, 2024, 4:02 AM Reply Quote 0
            • T
              thyroidchor27 @jamezb46
              last edited by Oct 8, 2024, 9:41 AM

              @jamezb46 I need to get lean i will do this.

              1 Reply Last reply Reply Quote 0
              • J
                jamezb46 @Insomniac
                last edited by Oct 10, 2024, 4:02 AM

                @Insomniac

                Ray thought that alot of the pregnenalone available as supplements was damaged in the production process. Apparently if you heat the P5 too high, estrogenic substances are generated. Ray thought that some of those were present in virutally all products available OTC.

                That's why he likes the progesterone better.

                In time there is life but no knowledge; outside time there is knowledge but no life

                I 1 Reply Last reply Oct 10, 2024, 2:27 PM Reply Quote 0
                • I
                  Insomniac @jamezb46
                  last edited by Oct 10, 2024, 2:27 PM

                  @jamezb46 said in P4 and DHEA in a 8:1 Ratio:

                  @Insomniac

                  Ray thought that alot of the pregnenalone available as supplements was damaged in the production process. Apparently if you heat the P5 too high, estrogenic substances are generated. Ray thought that some of those were present in virutally all products available OTC.

                  That's why he likes the progesterone better.

                  That make sense. Lots of pharma companies make progesterone.

                  Amazon has one usp progesterone powder but I don't see any usp pregnenolone.

                  1 Reply Last reply Reply Quote 0
                  • I
                    Insomniac
                    last edited by Oct 11, 2024, 10:19 AM

                    Does anyone know if the ratio is the same using pregnenolone?

                    J 1 Reply Last reply Oct 13, 2024, 1:34 AM Reply Quote 0
                    • J
                      jamezb46 @Insomniac
                      last edited by Oct 13, 2024, 1:34 AM

                      @Insomniac No it's 1:1

                      In time there is life but no knowledge; outside time there is knowledge but no life

                      I 1 Reply Last reply Oct 16, 2024, 8:21 AM Reply Quote 0
                      • I
                        Insomniac @jamezb46
                        last edited by Oct 16, 2024, 8:21 AM

                        @jamezb46 Thanks. I wouldn't have guessed right.

                        1 Reply Last reply Reply Quote 0
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