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Diclofenac gel to regrow hair on bald head and beard

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  • M
    Mossy @onliest
    last edited by Jan 14, 2025, 6:03 AM

    @onliest said in Diclofenac gel to regrow hair on bald head and beard:

    @Mossy what about GHK-cu dissolved in DMSO?

    GHK-cu is on my very long list of things to try (again). You may have read I did try copper peptides about 15 years ago, for about a 6 month stint. I do feel that it helped with hair color and maybe even retaining hair, but there is no way for me to tell for sure. But, during that time I also declined into the worst health state of my life. I can't necessarily blame copper peptides, because my life was very stressful at that time as well. I'm more apt to blame the stress than supplements. But, ever since that health decline I've never been the same. I can't take supplements like I used to.

    Purely from a cost and convenience perspective, I'm more apt to try Diclofenac than more expensive options, such as GHK-cu. If it weren't for the potential sides I would jump right in.

    "To desire action is to desire limitation" — G. K. Chesterton
    "The true step of health and improvement is slow." — Novalis

    O 1 Reply Last reply Jan 14, 2025, 1:48 PM Reply Quote 0
    • B
      BearWithMe
      last edited by Jan 14, 2025, 7:48 AM

      Treatment of alopecia areata by topical diclofenac sodium gel in comparison to benzoyl peroxide gel. A novel single blind therapeutic clinical trial
      ...
      Patients were instructed to apply topical 1% diclofenac sodium gel twice daily for 2 months to all affected patches with gentile massage.
      ...
      Few and tolerable adverse effects were observed during the course of the treatment of both topical gels, like erythema and itching, but these was resolved spontaneously during the course of the therapy without interrupting the treatment course
      ...
      The present study has proved its effectiveness in the treatment of AA as 21 (65.9%) patches showed complete hair regrowth at the end 4 months of follow up.
      ...
      The topical multiple successful therapy lead us to speculate that all of them
      work through the same mechanism by irritation of the keratinocyte of the hair follicles, and the epidermis to induce the release of immune mediators. These mediators will regulate the dysregulated immunity, hence, stimulating the arrested growth of hair bulb to regenerate again producing a normal coarse hair, this so called “irritant theory” could be applied to other skin diseases like vitiligo.

      https://smj.org.sa/content/smj/27/7/1079.full.pdf

      H 1 Reply Last reply Jan 15, 2025, 2:19 AM Reply Quote 0
      • B
        BearWithMe
        last edited by Jan 14, 2025, 9:59 AM

        There are two types of topical diclofenac, diclofenac diethylamine and diclofenac sodium. Diclofenac sodium was used in the available hair loss studies

        not all topical diclofenac formulations are the same

        H 1 Reply Last reply Jan 15, 2025, 2:23 AM Reply Quote 0
        • O
          onliest @Mossy
          last edited by Jan 14, 2025, 1:48 PM

          @Mossy DMSO is cheap. 1g of GHK-Cu is like $20. Cheaper to make your own. When you tried copper peptides, how did you take them?

          W M 2 Replies Last reply Jan 14, 2025, 2:51 PM Reply Quote 0
          • W
            wester130 @onliest
            last edited by wester130 Jan 14, 2025, 2:51 PM Jan 14, 2025, 2:51 PM

            @onliest

            i am currently doing

            caffeine,
            zinc PCA - suprisingly hard to find the powder but I did
            NMN, a form of niacin, not niacinamide

            will consider zinc thymulin//ghk

            1 Reply Last reply Reply Quote 0
            • H
              Hearthfire @BearWithMe
              last edited by Jan 15, 2025, 2:19 AM

              @BearWithMe wtf? that's insane regrowth

              1 Reply Last reply Reply Quote 0
              • H
                Hearthfire @BearWithMe
                last edited by Jan 15, 2025, 2:23 AM

                @BearWithMe the gels on amazon are Diclofenac sodium 1%

                M 1 Reply Last reply Jan 15, 2025, 7:08 AM Reply Quote 0
                • M
                  Mossy @onliest
                  last edited by Jan 15, 2025, 7:06 AM

                  @onliest said in Diclofenac gel to regrow hair on bald head and beard:

                  @Mossy DMSO is cheap. 1g of GHK-Cu is like $20. Cheaper to make your own. When you tried copper peptides, how did you take them?

                  Thanks for the info on the budgeted GHK-Cu. Do you have a link for the specific product? My saved link for GHK-Cu has it at $70 for 50mg. This is a product that a member on RPF used, where he would make a solution from this. I forget the specifics, but I'm sure it could be searched out on that forum.

                  When I used it, I purchased a pre-made product made to be applied topically to the scalp. I forget the name. It was fairly expensive.

                  "To desire action is to desire limitation" — G. K. Chesterton
                  "The true step of health and improvement is slow." — Novalis

                  O 1 Reply Last reply Jan 15, 2025, 12:47 PM Reply Quote 0
                  • M
                    Mossy @Hearthfire
                    last edited by Jan 15, 2025, 7:08 AM

                    @Hearthfire said in Diclofenac gel to regrow hair on bald head and beard:

                    @BearWithMe the gels on amazon are Diclofenac sodium 1%

                    Yes, this is what I'm finding as well. I'm only seeing the sodium variety, everywhere I look.

                    "To desire action is to desire limitation" — G. K. Chesterton
                    "The true step of health and improvement is slow." — Novalis

                    H B 2 Replies Last reply Jan 15, 2025, 7:23 AM Reply Quote 0
                    • H
                      Hearthfire @Mossy
                      last edited by Jan 15, 2025, 7:23 AM

                      @Mossy

                      Isn't that the best one though? based on the studies

                      M 1 Reply Last reply Jan 16, 2025, 11:55 AM Reply Quote 0
                      • B
                        BearWithMe @Mossy
                        last edited by Jan 15, 2025, 7:32 AM

                        @Mossy said in Diclofenac gel to regrow hair on bald head and beard:

                        @Hearthfire said in Diclofenac gel to regrow hair on bald head and beard:

                        @BearWithMe the gels on amazon are Diclofenac sodium 1%

                        Yes, this is what I'm finding as well. I'm only seeing the sodium variety, everywhere I look.

                        For example, Voltaren - the best selling and most popular Diclofenac gel - is diethylamine.

                        M 1 Reply Last reply Jan 16, 2025, 12:03 PM Reply Quote 0
                        • O
                          onliest @Mossy
                          last edited by Jan 15, 2025, 12:47 PM

                          @Mossy I was buying powder from a random company online. That's a great price. When I run out I'll try that source out.

                          There are a lot of brands selling GHK-cu products for huge sums. Trendy peptide rn.

                          M 1 Reply Last reply Jan 16, 2025, 12:08 PM Reply Quote 0
                          • M
                            Mossy @Hearthfire
                            last edited by Mossy Jan 16, 2025, 12:04 PM Jan 16, 2025, 11:55 AM

                            @Hearthfire said in Diclofenac gel to regrow hair on bald head and beard:

                            @Mossy

                            Isn't that the best one though? based on the studies

                            I only know what the links posted on this thread have shown. I am very new to Diclofenac and am learning along with everyone else. So, based on the SMJ study link, it does seem the sodium variation would be the one to try.

                            It is worth pointing out that the SMJ study linked above is for alopecia areata, not androgenetic alopecia, or male pattern baldness. That's not to say that this won't work for MPB, just pointing this out.

                            "To desire action is to desire limitation" — G. K. Chesterton
                            "The true step of health and improvement is slow." — Novalis

                            1 Reply Last reply Reply Quote 0
                            • M
                              Mossy @BearWithMe
                              last edited by Jan 16, 2025, 12:03 PM

                              @BearWithMe said in Diclofenac gel to regrow hair on bald head and beard:

                              @Mossy said in Diclofenac gel to regrow hair on bald head and beard:

                              @Hearthfire said in Diclofenac gel to regrow hair on bald head and beard:

                              @BearWithMe the gels on amazon are Diclofenac sodium 1%

                              Yes, this is what I'm finding as well. I'm only seeing the sodium variety, everywhere I look.

                              For example, Voltaren - the best selling and most popular Diclofenac gel - is diethylamine.

                              I am not seeing that. On Amazon, I see Votaren as the sodium variety:

                              "Active Ingredients: Diclofenac sodium (NSAID†) 1% (equivalent to 0.93% diclofenac) - Arthritis pain reliever. Nonsteroidal anti-inflammatory drug."

                              "To desire action is to desire limitation" — G. K. Chesterton
                              "The true step of health and improvement is slow." — Novalis

                              1 Reply Last reply Reply Quote 0
                              • M
                                Mossy @onliest
                                last edited by Jan 16, 2025, 12:08 PM

                                @onliest said in Diclofenac gel to regrow hair on bald head and beard:

                                @Mossy I was buying powder from a random company online. That's a great price. When I run out I'll try that source out.

                                There are a lot of brands selling GHK-cu products for huge sums. Trendy peptide rn.

                                Your pricing of $20 for a gram is much better. Maybe you didn't see the weight, but the link I sent shows $70 for 50mg. Yours is 20 times the amount for less than a third of the cost.

                                "To desire action is to desire limitation" — G. K. Chesterton
                                "The true step of health and improvement is slow." — Novalis

                                O 1 Reply Last reply Jan 16, 2025, 1:24 PM Reply Quote 0
                                • O
                                  onliest @Mossy
                                  last edited by Jan 16, 2025, 1:24 PM

                                  @Mossy oops yah I misread that as 50g. $70 for 50mg is insane lmao

                                  1 Reply Last reply Reply Quote 0
                                  • H
                                    Hearthfire
                                    last edited by Hearthfire Jan 27, 2025, 11:21 PM Jan 27, 2025, 11:21 PM

                                    I ordered some diclofenac gel from Amazon. I'll let you guys know how it goes.

                                    W 1 Reply Last reply Jan 28, 2025, 2:28 AM Reply Quote 0
                                    • W
                                      wester130 @Hearthfire
                                      last edited by Jan 28, 2025, 2:28 AM

                                      update on diclofenac

                                      i still got a terrible cough from using it and I think it triggered flu in me

                                      no one else in the household got flu
                                      it's powerful, dangerous stuff

                                      H 1 Reply Last reply Jan 28, 2025, 3:49 AM Reply Quote 0
                                      • H
                                        Hearthfire @wester130
                                        last edited by Jan 28, 2025, 3:49 AM

                                        @wester130

                                        From topical?

                                        1 Reply Last reply Reply Quote 0
                                        • B
                                          BearWithMe
                                          last edited by Jan 28, 2025, 5:08 AM

                                          I just received my tube of diclofenac, but got terrible tinnitus after first application to the scalp. Then I found this:

                                          https://www.reddit.com/r/tinnitus/comments/u1hl53/im_an_idiot_i_may_have_just_made_my_tinnitus/

                                          Ototoxicity associated with topical administration of diclofenac
                                          https://pubmed.ncbi.nlm.nih.gov/28583486/

                                          It might be a coincidence and not caused by the diclofenac, there is no reliable evidence of diclofenac being ototoxic when applied to the scalp. But there is evidence of general ototoxicity and n=2 reddit-post evidence of ototoxicity when applied to the scalp.

                                          I prefer to be bald over being deaf so even if there is 0,01% chance of hearing damage I'm going to err to the side of caution

                                          H 1 Reply Last reply Jan 28, 2025, 12:12 PM Reply Quote 0
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