DHT Enanthate
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@alfredoolivas And from that study:
In conclusion, our work demonstrates that the fat-burning action of T is dependent on aromatization into estrogens and is at least partially mediated by the stimulation of physical activity via extrahypothalamic ERα signaling.
That definitely won't go over well with some in this community that insist that estrogen is the enemy and DHT is good because it supposedly crashes it.
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@Crypt-Keeper Well whether estrogen is good or not, is up for debate, but for certain, estrogen is responsible for the fat loss properties of androgens. Everyone, not just people on this forum say, "estrogen is the fattening, pregnancy hormone!". Well show me a study of an aromatase inhibitor reversing obesity? I will wait!
https://www.sciencedirect.com/science/article/abs/pii/0031938479900453
"Treatment of castrated male rats with low doses of testosterone propionate (TP; 0.2 mg/day) increases food intake and body weight gain, but long-term treatment with a higher dose of TP (1 mg/day) reduces body weight gain and carcass fat content. Concurrent treatment with androsta-1,4,6-triene-3, 17-dione (ATD), which blocks the aromatization of androgens to estrogens, prevents the weight-reducing effects of high doses of TP. "
So basically this studied showed that, if you allow T to only turn into DHT instead of E + DHT, via blocking the aromatase enzyme, fat is gained.
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@alfredoolivas I wasn't advocating for the use of DHT without an estrogen precursor. The few people hyping up DHT Enanthate on twitter are using exogenous T and E2 alongside DHT.
https://x.com/BenWestgate_/status/1838407090739589474
https://x.com/solothesensei/status/1878763267038105872
https://x.com/BowTiedUM/status/1886096759832641778
Whether if it is just "hype" or not, estered hormones are going to out perform non estered hormones in its effects every single time.
I don't think it is that simple. The rapid peaks of base DHT saturates 3a-HSD and 3b-HSD enzymes which leads to immediate conversion to the inactive metabolites. DHT Enanthates esterification leads to a slower release into the bloodstream, reducing the peak concentration, prolonging the duration and increasing free DHT levels. This slower release means 3a-HSD and 3b-HSD enzymes are not overwhelmed with a large bolus of DHT at once, which would rapidly convert into the inactive metabolites. Instead the steady release allows DHT to remain active longer, as the enzymes are not as quickly saturated, leading to a higher free hormone level and a greater androgenic effect on tissues compared to the base form. Essentially the ester out competes the inactivation of DHT which is probably why these body re compositions are not being achieved on high doses of base DHT dissolved in either DMSO or Tocopherol.
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@dht said in DHT Enanthate:
The few people hyping up DHT Enanthate on twitter are using exogenous T and E2 alongside DHT.
Are there any good semi-legal-ish sources of E2? I'm definitely deficient and it's just awful.
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@Crypt-Keeper purple panda labs if you want raws
or potentially this
https://healthnatura.com/estrogen-oil-1-oz/ -
@sushi_is_cringe I was talking about cosmetic effects, not about DHT effect's on health issues. All those studies cover the latter
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@Crypt-Keeper yes as DHT said, PPL offers domestic shipping of estradiol within the US. So it doesn't go through customs, and you can order estradiol and receive it in a week. If you are outside of US, PPL offers international shipping, which is a bit slower, but the stealth shipping is really good, I have ordered 4 times from them, no issue.
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To say DHT isn't as good as test is hilarious based on a study with mice. If you have high prolactin, take dht over test but you should take both.
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@risingfire said in DHT Enanthate:
To say DHT isn't as good as test is hilarious based on a study with mice. If you have high prolactin, take dht over test but you should take both.
That is genius thinking! If you want to disregard animal studies, show me a study showing the benefits of DHT in HUMANS, and I will show you the benefits of TESTOSTERONE in HUMANS.
You won't be able to find any studies on DHT in humans, and I will be able to show you dozens of studies of testosterone showing benefits of testosterone in humans. Therefore, according to your way of evidence based way of thinking, my research is far superior to yours, as it is actually tested in humans.
If you want to disregard animal studies, that is absolutely fine, but then you need to admit that testosterone is better than DHT, because testosterone is actually studied in humans, whereas DHT isn't.
Edit: Can you even show DHT lowers prolactin (especially in humans as mice studies are useless right?) or is this just a twitter rumour?
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Edit: Can you even show DHT lowers prolactin (especially in humans as mice studies are useless right?) or is this just a twitter rumour?
Very easily
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2605.1984.tb00759.x
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@risingfire Thank you!
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@alfredoolivas have you taken DHT before?
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@risingfire I used close to 200mg daily on average, applied topically dissolved in DMSO, for 6 months. I have tried doses in the single mg range and doses up to 400mg.
