DHT Enanthate
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@dht are you the guy from twitter who posts his physique and workout clips and about dht?
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@sushi_is_cringe nope just somebody very interested in DHT.
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@dht DHT is pure hype when it comes to cosmetic purposes. If DHT had any cosmetic benefit, then at least one of the thousands of studies performed on DHT, would of shown it. But I have yet to see a single study showing any cosmetic benefit of DHT. I would stop showing interest in it, it's not a golden bullet, or a well-kept secret, but rather a hype train.
The guy behind the hype is also on testosterone as well.https://academic.oup.com/endo/article/162/6/bqab045/6155679
"Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling...Testosterone but not dihydrotestosterone decreases fat mass in obese hypogonadal male mice
https://pubmed.ncbi.nlm.nih.gov/16741268/
"DHT treatment resulted in obesity, associated with reduced energy expenditure and fat oxidation. "
https://www.sciencedirect.com/science/article/abs/pii/S1344622399800194
"In respiratory parameters, expired CO2 gas decreased significantly in the hormone-treated rats"
If you are going to reply with some anecdotal something, please don't. Not trying to be rude, but we should skip the talk and share studies instead, in order to hopefully dismiss these studies showing DHT having negative cosmetic effects, as I want DHT to have cosmetic purposes as much as the next person.
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@alfredoolivas And from that study:
In conclusion, our work demonstrates that the fat-burning action of T is dependent on aromatization into estrogens and is at least partially mediated by the stimulation of physical activity via extrahypothalamic ERα signaling.
That definitely won't go over well with some in this community that insist that estrogen is the enemy and DHT is good because it supposedly crashes it.
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@Crypt-Keeper Well whether estrogen is good or not, is up for debate, but for certain, estrogen is responsible for the fat loss properties of androgens. Everyone, not just people on this forum say, "estrogen is the fattening, pregnancy hormone!". Well show me a study of an aromatase inhibitor reversing obesity? I will wait!
https://www.sciencedirect.com/science/article/abs/pii/0031938479900453
"Treatment of castrated male rats with low doses of testosterone propionate (TP; 0.2 mg/day) increases food intake and body weight gain, but long-term treatment with a higher dose of TP (1 mg/day) reduces body weight gain and carcass fat content. Concurrent treatment with androsta-1,4,6-triene-3, 17-dione (ATD), which blocks the aromatization of androgens to estrogens, prevents the weight-reducing effects of high doses of TP. "
So basically this studied showed that, if you allow T to only turn into DHT instead of E + DHT, via blocking the aromatase enzyme, fat is gained.
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@alfredoolivas I wasn't advocating for the use of DHT without an estrogen precursor. The few people hyping up DHT Enanthate on twitter are using exogenous T and E2 alongside DHT.
https://x.com/BenWestgate_/status/1838407090739589474
https://x.com/solothesensei/status/1878763267038105872
https://x.com/BowTiedUM/status/1886096759832641778
Whether if it is just "hype" or not, estered hormones are going to out perform non estered hormones in its effects every single time.
I don't think it is that simple. The rapid peaks of base DHT saturates 3a-HSD and 3b-HSD enzymes which leads to immediate conversion to the inactive metabolites. DHT Enanthates esterification leads to a slower release into the bloodstream, reducing the peak concentration, prolonging the duration and increasing free DHT levels. This slower release means 3a-HSD and 3b-HSD enzymes are not overwhelmed with a large bolus of DHT at once, which would rapidly convert into the inactive metabolites. Instead the steady release allows DHT to remain active longer, as the enzymes are not as quickly saturated, leading to a higher free hormone level and a greater androgenic effect on tissues compared to the base form. Essentially the ester out competes the inactivation of DHT which is probably why these body re compositions are not being achieved on high doses of base DHT dissolved in either DMSO or Tocopherol.
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@dht said in DHT Enanthate:
The few people hyping up DHT Enanthate on twitter are using exogenous T and E2 alongside DHT.
Are there any good semi-legal-ish sources of E2? I'm definitely deficient and it's just awful.
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@Crypt-Keeper purple panda labs if you want raws
or potentially this
https://healthnatura.com/estrogen-oil-1-oz/ -
@sushi_is_cringe I was talking about cosmetic effects, not about DHT effect's on health issues. All those studies cover the latter
