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When to take Cyproheptadine for sleep?

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  • M
    mavuue
    last edited by Oct 17, 2024, 5:35 AM

    Hi all

    I got my hands on some Cyproheptadine yesterday, and I took 1.5mg about an hour before sleep... I couldn't sleep for about 4 hours after laying in bed, and ended up missing a lecture today because of it.

    I have read a small sum of anecdotes that report the same thing.
    For anyone that takes Cyproheptadine, whether it be for sleep, serotonin, histamine or anything, would you please let me know your dosing protocol? I don't want to risk this happening again.
    Thank you

    R O S 3 Replies Last reply Oct 17, 2024, 4:47 PM Reply Quote 0
    • R
      risingfire @mavuue
      last edited by Oct 17, 2024, 4:47 PM

      @mavuue start off with half a milli. The first day is always very difficult to wake up. It makes most sense to start on a day that's low key such as the weekend. I personally needed a ton of coffee to function in order to stay awake.

      M 1 Reply Last reply Oct 17, 2024, 10:57 PM Reply Quote 0
      • M
        mavuue @risingfire
        last edited by Oct 17, 2024, 10:57 PM

        @risingfire I had no issue waking up, the problem was actually falling asleep. How long before sleep should I take 0.5mg?

        D R 2 Replies Last reply Oct 18, 2024, 9:54 AM Reply Quote 0
        • O
          onliest @mavuue
          last edited by Oct 17, 2024, 11:51 PM

          @mavuue I'd recommend taking 0.5mg right after sunset

          1 Reply Last reply Reply Quote 0
          • D
            DkJoe2 @mavuue
            last edited by Oct 18, 2024, 9:54 AM

            @mavuue you may find it's spiking your adrenals where it's dropping cortisol and you have no other hormones to fill the gap and it may not be a timing issue. Cypro typically saps the energy of people initially making it hard to get out of bed and focus. Maybe try taking it at the same time but eat a good portion of carbs/fat with it and see how you go?

            O 1 Reply Last reply Oct 18, 2024, 10:56 AM Reply Quote 0
            • O
              onliest @DkJoe2
              last edited by Oct 18, 2024, 10:56 AM

              @DkJoe2 I concur with this. Have some ice cream. Only take 0.5mg 2-3 times a week. Preferably on days you are working out

              1 Reply Last reply Reply Quote 0
              • R
                risingfire @mavuue
                last edited by Oct 18, 2024, 3:17 PM

                @mavuue I'd wait until you feel your dopamine has recovered completely. Cypro seems reduce dopamine and serotonin

                M 1 Reply Last reply Oct 20, 2024, 1:17 PM Reply Quote 0
                • S
                  serotoninskeptic @mavuue
                  last edited by Oct 18, 2024, 3:59 PM

                  @mavuue Right before bed. It hits pretty fast

                  1 Reply Last reply Reply Quote 0
                  • M
                    Milk Destroyer @risingfire
                    last edited by Oct 20, 2024, 1:17 PM

                    @risingfire I always thought cypro was actually agonistic of dopamine? At least, when you are eating enough good food alongside it.

                    R D 2 Replies Last reply Oct 22, 2024, 1:55 PM Reply Quote 0
                    • R
                      risingfire @Milk Destroyer
                      last edited by Oct 22, 2024, 1:55 PM

                      @Milk-Destroyer all the literature I've read and personal experience has proved quite the opposite. I wonder if taking lisuride alongside cypro may negate those side effects

                      M 1 Reply Last reply Oct 22, 2024, 4:25 PM Reply Quote 0
                      • M
                        Milk Destroyer @risingfire
                        last edited by Oct 22, 2024, 4:25 PM

                        @risingfire If only lisuride was cheaply and easily available, as cypro is in a lot of countries.

                        D 1 Reply Last reply Oct 22, 2024, 6:36 PM Reply Quote 0
                        • D
                          DkJoe2 @Milk Destroyer
                          last edited by Oct 22, 2024, 6:34 PM

                          @Milk-Destroyer I may be wrong but I loosely remember it being something to do with Serotonin and Dopamine being conversely related but also staying within a certain range of each other?
                          So at higher doses Cypro drops Serotonin off a cliff which surges Dopamine to a point but if Serotonin falls too far Dopamine also reduces with it, dopamine should always remain higher though (providing there is adequate nutrition/rest of course otherwise it's adrenaline time).

                          Fyi good chance I have remembered/understood this wrong though.

                          1 Reply Last reply Reply Quote 0
                          • D
                            DkJoe2 @Milk Destroyer
                            last edited by Oct 22, 2024, 6:36 PM

                            @Milk-Destroyer l-dopa or tyrosine with sunlight maybe?

                            R M 2 Replies Last reply Oct 23, 2024, 12:53 PM Reply Quote 0
                            • R
                              risingfire @DkJoe2
                              last edited by Oct 23, 2024, 12:53 PM

                              @DkJoe2 +1

                              1 Reply Last reply Reply Quote 0
                              • M
                                Milk Destroyer @DkJoe2
                                last edited by Oct 24, 2024, 7:35 PM

                                @DkJoe2 I wonder if exogenous l-dopa would convert instead to adrenaline though? And is tyrosine use safe, it being a standalone amino-acid? I suppose it'd be a matter of individual experimentation

                                1 Reply Last reply Reply Quote 0
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