Diclofenac gel to regrow hair on bald head and beard
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@wester130 that was interesting, and something that always rings an alarm for me is when it aligns with something Peat had mentioned. In this case I couldn’t help but think of the story of the man who regrew his hair when he fell in the fireplace and burned his scalp. I mean all he did was essentially give himself a very painful peel right?
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@evan.hinkle removing the old collagen can be helpful, yes, by forcing fresher collagen to be produced
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retinol only for hair growth??? maybe it is a collagen problem
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@wester130 retinol also supposedly has a role in thyroid transport (I think t3)
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@wester130 I forget the exact time period — maybe 7-10 years ago — there was a time when people were putting Retin-A on their scalps for potential hair growth. Retin-A is just what it sounds like, used by dermatologists to recondition skin. Back when I read about it, to my layman's mind, I assumed the Retin-A was just working similarly to salicylic acid, reconditioning the scalp, which was very popular in the hair loss community for a while; but maybe there was something to the vitamin A itself, not just the resurfacing.
For what it's worth, I feel like food based vitamin A, via liver, is one of the best Peaty things yet for me. I definitively feel noticeably better on it, with no side effects. I've just been thinking about this recently, about attempting to consume more liver for more vitamin A. They say your body craves what it needs.
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@Mossy many companies are mixing Minoxidil with treitinoin, so it is positively affecting the collagen
i am not sure of what mechanism, maybe inflammation, maybe improving collagen,
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I think treitinoin helps absorption, but also:
Chat GPT says:
Tretinoin (a retinoid) increases skin cell turnover and thins the outermost layer of the skin (stratum corneum), which can:
Increase scalp permeability
Allow more minoxidil to reach the folliclesMinoxidil must be converted into minoxidil sulfate by an enzyme in the scalp called sulfotransferase.
Some research suggests tretinoin may:
Increase sulfotransferase activitySome peoples scalps don't have enough sulfotransferase, therefore treitinoin is used topically to convert it.
Alternatively, oral minoxdil can be taken if you're a non-responder to topical, because the liver has abundant sulfotransferase enzymes.
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"In reference to the man who fell in a fireplace and regrew his hair - you can actually get your scalp skin burned off.
It is called a phenol peel, far stronger than an ordinary chemical peel.
It is not sold online, you cannot buy the ingredients, only specialist beauty centers will offer it." -
has anyone ever considered scar gels for hair loss?
there is a lot of overlap with healing the skin and TGFb-1
many of them contain interesting ingredients that would stop inflammation in the scalp
