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    Fenclonine

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    • engineerE Offline
      engineer @alfredoolivas
      last edited by engineer

      @alfredoolivas said in Fenclonine:

      Watch engineer smash all the tortas in Miami now

      Speak of the devil except not in Miami

      alfredoolivasA 1 Reply Last reply Reply Quote 1
      • alfredoolivasA Offline
        alfredoolivas @engineer
        last edited by

        @engineer I’m sure the taladafil came in handy

        engineerE 1 Reply Last reply Reply Quote 0
        • engineerE Offline
          engineer @alfredoolivas
          last edited by

          @alfredoolivas it hasn't quite happened yet but could soon.

          alfredoolivasA 1 Reply Last reply Reply Quote 1
          • hwisdomH Offline
            hwisdom @hwisdom
            last edited by

            selegiline is btw rlly goated it does live to the hype, better than bromantane imo

            MILF
            man I love fasting

            1 Reply Last reply Reply Quote 1
            • alfredoolivasA Offline
              alfredoolivas @engineer
              last edited by

              @engineer inshallah

              engineerE 1 Reply Last reply Reply Quote 0
              • engineerE Offline
                engineer
                last edited by

                If pramipexole doesn't work out, it looks like you can also increase dopamine and (hopefully) lower serotonin through MCR agonism. That would mean a peptide like melanotan 2 or PT-141. I already have some melanotan 2 but the jury is still out on melanoma risk so that means PT-141.

                hwisdomH jamezb46J 2 Replies Last reply Reply Quote 0
                • engineerE Offline
                  engineer
                  last edited by

                  Looks lik maybe MCR agonism is akin to a stress response?

                  Appears as though metergoline is the way to go even though it mostly works on serotonin

                  Now the challenge is finding bulk metergoline

                  hwisdomH 1 Reply Last reply Reply Quote 0
                  • hwisdomH Offline
                    hwisdom @engineer
                    last edited by

                    @engineer melanotan makes you black through NO stimulation btw, this is why it also gives u massive boners, prolactinogenic, not peaty, fuck melanotan all these mechanisms abt it are just speculations because "erm akshually melanin good!", didnt peter thiel like fund these popular peptides or smth idfk

                    MILF
                    man I love fasting

                    engineerE 1 Reply Last reply Reply Quote 0
                    • hwisdomH Offline
                      hwisdom @engineer
                      last edited by

                      @engineer metergoline is goated, any chinese nigga on echemi would sell it to you for around like 400$ a gram, 4mg a day for me gave me all the famous benefits of blocking serotonin at a significant rate, but if you can try getting ur hands on the brand name Liserdol product, its gonna be much easier

                      MILF
                      man I love fasting

                      1 Reply Last reply Reply Quote 0
                      • engineerE Offline
                        engineer @hwisdom
                        last edited by engineer

                        @hwisdom it doesnt specifically touch NO, it just stimulates melanocytes through mc1r which is normally agonized by alpha msh, and NO increases mc1r expression like you would expect in a stress state

                        https://grok.com/share/c2hhcmQtMw_7fd6d676-eb61-41b6-8bff-c75dc29acb22

                        remember, iNOS is bad and eNOS is fine

                        1 Reply Last reply Reply Quote 0
                        • engineerE Offline
                          engineer @alfredoolivas
                          last edited by engineer

                          @alfredoolivas said in Fenclonine:

                          @engineer inshallah

                          I just gave mami a Ray Peat starter kit

                          20260424_145843.webp

                          alfredoolivasA hwisdomH 2 Replies Last reply Reply Quote 2
                          • alfredoolivasA Offline
                            alfredoolivas @engineer
                            last edited by

                            @engineer you don’t cheap out, I like it

                            1 Reply Last reply Reply Quote 1
                            • hwisdomH Offline
                              hwisdom @engineer
                              last edited by

                              @engineer I eat out my dogs asshole

                              MILF
                              man I love fasting

                              1 Reply Last reply Reply Quote 0
                              • jamezb46J Offline
                                jamezb46 @engineer
                                last edited by

                                @engineer Maybe you would like Bupropion for this purpose. It's easily available.

                                In time there is life but no knowledge; outside time there is knowledge but no life

                                hwisdomH 1 Reply Last reply Reply Quote 0
                                • hwisdomH Offline
                                  hwisdom @jamezb46
                                  last edited by

                                  @jamezb46 it blocks serotonin like that???

                                  MILF
                                  man I love fasting

                                  jamezb46J 1 Reply Last reply Reply Quote 0
                                  • jamezb46J Offline
                                    jamezb46 @hwisdom
                                    last edited by

                                    @hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.

                                    In time there is life but no knowledge; outside time there is knowledge but no life

                                    alfredoolivasA hwisdomH 2 Replies Last reply Reply Quote 0
                                    • alfredoolivasA Offline
                                      alfredoolivas @jamezb46
                                      last edited by

                                      This post is deleted!
                                      1 Reply Last reply Reply Quote 0
                                      • W Online
                                        wester130 @engineer
                                        last edited by

                                        @engineer extremely difficult to buy from those websites

                                        engineerE 1 Reply Last reply Reply Quote 0
                                        • engineerE Offline
                                          engineer @wester130
                                          last edited by engineer

                                          @wester130 what exactly is extremely difficult to buy?

                                          1 Reply Last reply Reply Quote 0
                                          • hwisdomH Offline
                                            hwisdom @jamezb46
                                            last edited by

                                            @jamezb46 said in Fenclonine:

                                            @hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.

                                            ok thought so, thought it was smth like metergoline

                                            MILF
                                            man I love fasting

                                            1 Reply Last reply Reply Quote 0

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