Fenclonine
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@alfredoolivas it hasn't quite happened yet but could soon.
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selegiline is btw rlly goated it does live to the hype, better than bromantane imo
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@engineer inshallah
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If pramipexole doesn't work out, it looks like you can also increase dopamine and (hopefully) lower serotonin through MCR agonism. That would mean a peptide like melanotan 2 or PT-141. I already have some melanotan 2 but the jury is still out on melanoma risk so that means PT-141.
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Looks lik maybe MCR agonism is akin to a stress response?
Appears as though metergoline is the way to go even though it mostly works on serotonin
Now the challenge is finding bulk metergoline
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@engineer melanotan makes you black through NO stimulation btw, this is why it also gives u massive boners, prolactinogenic, not peaty, fuck melanotan all these mechanisms abt it are just speculations because "erm akshually melanin good!", didnt peter thiel like fund these popular peptides or smth idfk
MILF
man I love fasting -
@engineer metergoline is goated, any chinese nigga on echemi would sell it to you for around like 400$ a gram, 4mg a day for me gave me all the famous benefits of blocking serotonin at a significant rate, but if you can try getting ur hands on the brand name Liserdol product, its gonna be much easier
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@hwisdom it doesnt specifically touch NO, it just stimulates melanocytes through mc1r which is normally agonized by alpha msh, and NO increases mc1r expression like you would expect in a stress state
https://grok.com/share/c2hhcmQtMw_7fd6d676-eb61-41b6-8bff-c75dc29acb22
remember, iNOS is bad and eNOS is fine
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@engineer you don’t cheap out, I like it
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@engineer I eat out my dogs asshole
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@engineer Maybe you would like Bupropion for this purpose. It's easily available.
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@jamezb46 it blocks serotonin like that???
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@hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.
In time there is life but no knowledge; outside time there is knowledge but no life
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@engineer extremely difficult to buy from those websites
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@wester130 what exactly is extremely difficult to buy?
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@jamezb46 said in Fenclonine:
@hwisdom It doesn't block serotonin but it increases dopamine and as Georgi has written many times whenever dopamine increases serotonin tends to decrease because of enzyme competition. There are exceptions but in general the above is true as a rule.
ok thought so, thought it was smth like metergoline
