I think an reaction system on the forum would be beneficial in many ways, maybe that's just me but sometimes it's too taxing to write a full blown reply to a short but helpful comment that provided interesting information or the ultimate solution to the problem of the discussion.

@dfrank i was thinking about the same thing. lol.

@notmcas i used to have the same problem and i lost weight quickly by fasting and strict calorie restriction not realizing that i was hypothyroid and had mild insulin resistance, i lost mostly muscle and created a lot of hormonal imbalances, do not recommend.

There was a radio channel on the internet that played interviews with Dr. Peat, for some reason it has been down for a a few months now. What happened?

I'm having a lot of unexplained nervousness, stress and fast heart rate after taking nicotine and drinking coffee. What could be the reason to that? Should I ramp up my calcium intake to combat this? L-theanine? I think it may be a hypothyroidism symptom.

@yerrag it's such a shame, i think you can find a lot of your collection at zlib org.

@Nikolai Another problem of this study is that they fed the rats halibut fish oil.

The rats could also get deficient in biotin.

This study was done poorly, it does not confirm any side of the argument.

@Nikolai I think you are just putting words in his mouth. He said that polyunsaturated fatty acids are not essential at all.

He also said that restoring the metabolic function uses up more nutrients (hence why he argued that it was a B6 problem). My hypothesis is that bringing the metabolic rate up, the rats got deficient in some other vitamin/mineral like zinc, and they didn't test that.

Peat said that the Burrs study (where they gave rats a PUFA-free diet) were actually a Vitamin B6 deficiency. The whole thing can be found here: https://youtu.be/Oc1ijSN220k?si=Evj_3i_T-fwjeRgi.

They conducted an experiment in 1938 giving the rats moderate-high doses of B6 on that diet: https://www.sciencedirect.com/science/article/pii/S0021925818740386?ref=pdf_download&fr=RR-2&rr=8749d4922a114534. And it failed miserably, only giving the rats PUFA was the cure.

Does that suggest there is a minimum of PUFA for the organism to function? I can't seem to find any answers. Was Peat wrong about avoiding them completely?

@CO3 yeah, the hormonal profile really messes up the scar formation. I got these scars when i was literally PUFAnated and estrogenated eating junk food and not moving at all during quarantine. I gave myself insulin resistance and hypothyroidism at that time and a couple other issues. I'm working on fixing them, thanks for the suggestions. Progest is definetely on my shopping list for my high e2.