I've been taking T3 (Cynomel) for almost 4 weeks now. I'm currently taking a quarter of a Cynomel at a time so ~6mcg. I take them around 3-4 hours apart.

When I take it my temperature increases and there's a good feeling in my chest. But it seems like this effect is more short lived everyday.

Should I take more, or take it more often? I'm already taking two grains a day, sometimes more. Or does this indicate some other problem?

@Galaroc Thanks for the links, I will have a read. Currently I've stopped taking T3 and am going to try and improve my diet before I try again.

Interestingly I haven't taken any today and my temperature is currently 36.7 C

@Galaroc not stressed out at all but my diet isn't great. Can you tell me more about circulating FFAs? This is caused by eating a lot of PUFAs? How do they negate T3?

@BroJonas Cholesterol was slightly high last I checked, vitamin D low. What exactly does aspirin do and what do you guys mean when you talk about using it, like how much aspirin should I be taking and what effect is it meant to have? I've been taking one or two 100mg tablets a day recently.

I've been taking T3 for two weeks now, around half a Cynomel a day (spaced out over multiple doses every couple of hours). My temperatures haven't come up and I still get weird sensations in my chest. Is it safe to say it isn't working for me and I need to stop and figure out what else is wrong? Or should I stick with it a little longer? Should I increase the dose?

@cs3000 I've only tried doses between 1mcg - 4mcg. I'd be too scared to try higher doses because of the heart symptoms. I think I need to stop taking ADHD meds before I experiment anymore.

@Mulloch94 I haven't tried pregnenolone. I'm not sure I ever really had ADHD or whether I believe in it anymore. I'm hoping thyroid will solve what I thought was ADHD. I'm already on less than 5mg a day but I need to rip off the bandaid soon and stop completely. Thanks for your advice.

I should've said in the OP, I'm prescribed dexamphetamine for ADHD. I've been tapering down for a while but every time I stop completely I'm too dopey and tired to focus at work. But I'm down to <5mg a day now. The chest feeling I've been getting from thyroid is similar to a feeling I get when I stop ADHD meds completely, which also happens at night. I would also assume my cortisol levels must be relatively high if I'm taking speed everyday.

@Mulloch94 said in T3 causing weird feeling in chest at night:

Also the cortisol thing Peat was talking about was after meals, not after thyroid supplementation.

Would thyroid supplementation not have a similar effect? If not then can you speculate on what else might cause either/both of my symptoms?

@Mulloch94 I've been taking ~300mg magnesium every night before bed for years, and occasionally ~100-300mg during the day as well, so I would be surprised if not enough magnesium is the problem.

@Master How long have you been taking it? And do you get it at night as well or soon after taking it?